1ASZAB

The active site of yeast aspartyl-trna synthetase: structural and functional aspects of the aminoacylation reaction
Link type Probability Chain A piercings Chain B piercings
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Unlink Unlink 49% +338B -485B +519B -547B
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Unlink Unlink 49% +338B -485B +519B -547B
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Unlink Unlink 49% +338B -485B +519B -547B
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Unlink Unlink 49% +338B -485B +519B -547B
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Unlink Unlink 49% +338B -485B +519B -547B
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Unlink Unlink 49% +338B -485B +519B -547B
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Unlink Unlink 49% +338B -485B +519B -547B
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Unlink Unlink 49% +338B -485B +519B -547B
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Unlink Unlink 49% +338B -485B +519B -547B
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Unlink Unlink 49% +338B -485B +519B -547B
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Unlink Unlink 49% +338B -485B +519B -547B
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Unlink Unlink 49% +338B -485B +519B -547B
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Unlink Unlink 49% +338B -485B +519B -547B
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Unlink Unlink 49% +338B -485B +519B -547B
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Unlink Unlink 49% +338B -485B +519B -547B
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Unlink Unlink 49% +338B -485B +519B -547B
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Unlink Unlink 49% +338B -485B +519B -547B
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Unlink Unlink 49% +338B -485B +519B -547B
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Unlink Unlink 49% +338B -485B +519B -547B
Interpreting sequences
Chain A Sequence
EDTAKDNYGKLPLIQSRDSDRTGQKRVKFVDLDEAKDSDKEVLFRARVHNTRQQGATLAFLTLRQQASLIQGLVKANKEGTISKNMVKWAGSLNLESIVLVRGIVKKVDEPIKSATVQNLEIHITKIYTISETPEALPILLEDASRSEAEAEAAGLPVVNLDTRLDYRVIDLRTVTNQAIFRIQAGVCELFREYLATKKFTEVHTPKLLGAPSEGGSSVFEVTYFKGKAYLAQSPQFNKQQLIVADFERVYEIGPVFRAENSNTHRHMTEFTGLDMEMAFEEHYHEVLDTLSELFVFIFSELPKRFAHEIELVRKQYPVEEFKLPKDGKMVRLTYKEGIEMLRAAGKEIGDFEDLSTENEKFLGKLVRDKYDTDFYILDKFPLEIRPFYTMPDPANPKYSNSYDFFMRGEEILSGAQRIHDHALLQERMKAHGLSPEDPGLKDYCDGFSYGCPPHAGGGIGLERVVMFYLDLKNIRRASLFPRDPKRLRP
Chain A Sequence
EDTAKDNYGKLPLIQSRDSDRTGQKRVKFVDLDEAKDSDKEVLFRARVHNTRQQGATLAFLTLRQQASLIQGLVKANKEGTISKNMVKWAGSLNLESIVLVRGIVKKVDEPIKSATVQNLEIHITKIYTISETPEALPILLEDASRSEAEAEAAGLPVVNLDTRLDYRVIDLRTVTNQAIFRIQAGVCELFREYLATKKFTEVHTPKLLGAPSEGGSSVFEVTYFKGKAYLAQSPQFNKQQLIVADFERVYEIGPVFRAENSNTHRHMTEFTGLDMEMAFEEHYHEVLDTLSELFVFIFSELPKRFAHEIELVRKQYPVEEFKLPKDGKMVRLTYKEGIEMLRAAGKEIGDFEDLSTENEKFLGKLVRDKYDTDFYILDKFPLEIRPFYTMPDPANPKYSNSYDFFMRGEEILSGAQRIHDHALLQERMKAHGLSPEDPGLKDYCDGFSYGCPPHAGGGIGLERVVMFYLDLKNIRRASLFPRDPKRLRP
sequence length 490,490
structure length 490,490
publication title The active site of yeast aspartyl-tRNA synthetase: structural and functional aspects of the aminoacylation reaction.
pubmed rcsb
molecule tags Complex (aminoacyl-trna synthase/trna)
molecule keywords T-RNA (75-MER)
source organism Saccharomyces cerevisiae
ec nomenclature ec 6.1.1.12: Aspartate--tRNA ligase.
ec 6.1.1.12: Aspartate--tRNA ligase.
pdb deposition date1995-01-19
LinkProt deposition date2016-08-17

pfam database annotations

chain Pfam Accession CodePfam Family IdentifierPfam Description
AB PF00152 tRNA-synt_2tRNA synthetases class II (D, K and N)
AB PF01336 tRNA_anti-codonOB-fold nucleic acid binding domain
AB PF00152 tRNA-synt_2tRNA synthetases class II (D, K and N)
AB PF01336 tRNA_anti-codonOB-fold nucleic acid binding domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.40.50.140 Mainly Beta Beta Barrel OB fold (Dihydrolipoamide Acetyltransferase, E2P) Nucleic acid-binding proteins 1aszA01
3.30.930.10 Alpha Beta 2-Layer Sandwich BirA Bifunctional Protein; domain 2 Bira Bifunctional Protein; Domain 2 1aszA02
2.40.50.140 Mainly Beta Beta Barrel OB fold (Dihydrolipoamide Acetyltransferase, E2P) Nucleic acid-binding proteins 1aszB01
3.30.930.10 Alpha Beta 2-Layer Sandwich BirA Bifunctional Protein; domain 2 Bira Bifunctional Protein; Domain 2 1aszB02
1ASZAB 1ASYAB 1ATIAB
chains in the LinkProt database with same CATH superfamily
1ASYAB 1ATIAB 1Y8PAB 1Y8NAB 1ASZAB 1Y8OAB 1SNDAB
chains in the LinkProt database with same CATH topology
1ASZAB 1ASYAB 1ATIAB
chains in the LinkProt database with same CATH homology


 
#chains in the LinkProt database with same CATH superfamily
 1ASZ AB;  1ASY AB;  1ATI AB; 
#chains in the LinkProt database with same CATH topology
 1ASY AB;  1ATI AB;  1Y8P AB;  1Y8N AB;  1ASZ AB;  1Y8O AB;  1SND AB; 
#chains in the LinkProt database with same CATH homology
 1ASZ AB;  1ASY AB;  1ATI AB; 

6OD8A 6OD8B 4J15A 4J15B 1EOVA 5Y6LE 3I7FA 3I7FB 1ASZB 1ASYA 1ASYB 6IY6A 6IY6B 6IY6G 6IY6H 6OD8A 6OD8B 4J15A 4J15B 1EOVA 5Y6LE 3I7FA 3I7FB 1ASZA 1ASYA 1ASYB 6IY6A 6IY6B 6IY6G 6IY6H
similar chains in the pdb database (40% sequence similarity)

 
            
               
               
           
#similar chains in the pdb database (40% sequence similarity)
 6OD8_A;  6OD8_B;  4J15_A;  4J15_B;  1EOV_A;  5Y6L_E;  3I7F_A;  3I7F_B;  1ASZ_B;  1ASY_A;  1ASY_B;  6IY6_A;  6IY6_B;  6IY6_G;  6IY6_H;  6OD8_A;  6OD8_B;  4J15_A;  4J15_B;  1EOV_A;  5Y6L_E;  3I7F_A;  3I7F_B;  1ASZ_A;  1ASY_A;  1ASY_B;  6IY6_A;  6IY6_B;  6IY6_G;  6IY6_H; 
           

LinkProt | Interdisciplinary Laboratory of Biological Systems Modelling