3JZ4AB

Crystal structure of e. coli nadp dependent enzyme
Link type Probability Chain A piercings Chain B piercings
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Unlink Unlink 40% -122B +143B -127A +140A
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Unlink Unlink 40% -122B +143B -127A +140A
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Unlink Unlink 40% -122B +143B -127A +140A
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Unlink Unlink 40% -122B +143B -127A +140A
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Unlink Unlink 40% -122B +143B -127A +140A
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Unlink Unlink 40% -122B +143B -127A +140A
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Unlink Unlink 40% -122B +143B -127A +140A
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Unlink Unlink 40% -122B +143B -127A +140A
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Unlink Unlink 40% -122B +143B -127A +140A
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Unlink Unlink 40% -122B +143B -127A +140A
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Unlink Unlink 40% -122B +143B -127A +140A
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Unlink Unlink 40% -122B +143B -127A +140A
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Unlink Unlink 40% -122B +143B -127A +140A
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Unlink Unlink 40% -122B +143B -127A +140A
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Unlink Unlink 40% -122B +143B -127A +140A
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Unlink Unlink 40% -122B +143B -127A +140A
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Unlink Unlink 40% -122B +143B -127A +140A
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Unlink Unlink 40% -122B +143B -127A +140A
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Unlink Unlink 40% -122B +143B -127A +140A
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Unlink Unlink 40% -122B +143B -127A +140A
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Unlink Unlink 40% -122B +143B -127A +140A
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Unlink Unlink 40% -122B +143B -127A +140A
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Unlink Unlink 40% -122B +143B -127A +140A
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Unlink Unlink 40% -122B +143B -127A +140A
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Unlink Unlink 40% -122B +143B -127A +140A
Interpreting sequences
Chain A Sequence
KLNDSNLFRQQALINGEWLDANNGEAIDVTNPANGDKLGSVPKMGADETRAAIDAANRALPAWRALTAKERATILRNWFNLMMEHQDDLARLMTLEQGKPLAEAKGEISYAASFIEWFAEEGKRIYGDTIPGHQADKRLIVIKQPIGVTAAITPWNFPAAMITRKAGPALAAGCTMVLKPASQTPFSALALAELAIRAGVPAGVFNVVTGSAGAVGNELTSNPLVRKLSFTGSTEIGRQLMEQCAKDIKKVSLELGGNAPFIVFDDADLDKAVEGALASKFRNAGQTCVCANRLYVQDGVYDRFAEKLQQAMSKLHIGDGLDNGVTIGPLIDEKAVAKVEEHIADALEKGARVVCGGKAHERGGNFFQPTILVDVPANAKVSKEETFGPLAPLFRFKDEADVIAQANDTEFGLAAYFYARDLSRVFRVGEALEYGIVGINTGIISNEVAPFGGIKASGLGREGSKYGIEDYLEIKYMCIGL
Chain A Sequence
KLNDSNLFRQQALINGEWLDANNGEAIDVTNPANGDKLGSVPKMGADETRAAIDAANRALPAWRALTAKERATILRNWFNLMMEHQDDLARLMTLEQGKPLAEAKGEISYAASFIEWFAEEGKRIYGDTIPGHQADKRLIVIKQPIGVTAAITPWNFPAAMITRKAGPALAAGCTMVLKPASQTPFSALALAELAIRAGVPAGVFNVVTGSAGAVGNELTSNPLVRKLSFTGSTEIGRQLMEQCAKDIKKVSLELGGNAPFIVFDDADLDKAVEGALASKFRNAGQTCVCANRLYVQDGVYDRFAEKLQQAMSKLHIGDGLDNGVTIGPLIDEKAVAKVEEHIADALEKGARVVCGGKAHERGGNFFQPTILVDVPANAKVSKEETFGPLAPLFRFKDEADVIAQANDTEFGLAAYFYARDLSRVFRVGEALEYGIVGINTGIISNEVAPFGGIKASGLGREGSKYGIEDYLEIKYMCIGL
sequence length 481,481
structure length 481,481
publication title The X-ray crystal structure of Escherichia coli succinic semialdehyde dehydrogenase; structural insights into NADP+/enzyme interactions.
pubmed doi rcsb
molecule tags Oxidoreductase
molecule keywords Succinate-semialdehyde dehydrogenase [NADP+]
source organism Escherichia coli
ec nomenclature ec 1.2.1.79: Succinate-semialdehyde dehydrogenase (NADP(+)).
ec 1.2.1.79: Succinate-semialdehyde dehydrogenase (NADP(+)).
pdb deposition date2009-09-22
LinkProt deposition date2016-08-17

pfam database annotations

chain Pfam Accession CodePfam Family IdentifierPfam Description
AB PF00171 AldedhAldehyde dehydrogenase family
AB PF00171 AldedhAldehyde dehydrogenase family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.309.10 Alpha Beta 3-Layer(aba) Sandwich Aldehyde Dehydrogenase; Chain A, domain 2 Aldehyde Dehydrogenase; Chain A, domain 2 3jz4A02
3.40.605.10 Alpha Beta 3-Layer(aba) Sandwich Aldehyde Dehydrogenase; Chain A, domain 1 Aldehyde Dehydrogenase; Chain A, domain 1 3jz4A01
3.40.309.10 Alpha Beta 3-Layer(aba) Sandwich Aldehyde Dehydrogenase; Chain A, domain 2 Aldehyde Dehydrogenase; Chain A, domain 2 3jz4B02
3.40.605.10 Alpha Beta 3-Layer(aba) Sandwich Aldehyde Dehydrogenase; Chain A, domain 1 Aldehyde Dehydrogenase; Chain A, domain 1 3jz4B01
1A4SAD 1A4SBCD 3JZ4AB 1A4SAB 3JZ4ABD 1A4SACD 1A4SBD 1A4SBC 3JZ4BC 3JZ4ACD 1A4SAC 3JZ4BD 1A4SABC 3JZ4CD 3JZ4AC 3JZ4BCD 3JZ4ABC 1A4SABD 1A4SCD
chains in the LinkProt database with same CATH superfamily
1A4SAD 1A4SBCD 3JZ4AB 1A4SAB 3JZ4ABD 1A4SACD 1A4SBD 1A4SBC 3JZ4BC 3JZ4ACD 1A4SAC 3JZ4BD 1A4SABC 3JZ4CD 3JZ4AC 3JZ4BCD 3JZ4ABC 1A4SABD 1A4SCD
chains in the LinkProt database with same CATH topology
1A4SAD 1A4SBCD 3JZ4AB 1A4SAB 3JZ4ABD 1A4SACD 1A4SBD 1A4SBC 3JZ4BC 3JZ4ACD 1A4SAC 3JZ4BD 1A4SABC 3JZ4CD 3JZ4AC 3JZ4BCD 3JZ4ABC 1A4SABD 1A4SCD
chains in the LinkProt database with same CATH homology


 
#chains in the LinkProt database with same CATH superfamily
 1A4S AD;  1A4S BCD;  3JZ4 AB;  1A4S AB;  3JZ4 ABD;  1A4S ACD;  1A4S BD;  1A4S BC;  3JZ4 BC;  3JZ4 ACD;  1A4S AC;  3JZ4 BD;  1A4S ABC;  3JZ4 CD;  3JZ4 AC;  3JZ4 BCD;  3JZ4 ABC;  1A4S ABD;  1A4S CD; 
#chains in the LinkProt database with same CATH topology
 1A4S AD;  1A4S BCD;  3JZ4 AB;  1A4S AB;  3JZ4 ABD;  1A4S ACD;  1A4S BD;  1A4S BC;  3JZ4 BC;  3JZ4 ACD;  1A4S AC;  3JZ4 BD;  1A4S ABC;  3JZ4 CD;  3JZ4 AC;  3JZ4 BCD;  3JZ4 ABC;  1A4S ABD;  1A4S CD; 
#chains in the LinkProt database with same CATH homology
 1A4S AD;  1A4S BCD;  3JZ4 AB;  1A4S AB;  3JZ4 ABD;  1A4S ACD;  1A4S BD;  1A4S BC;  3JZ4 BC;  3JZ4 ACD;  1A4S AC;  3JZ4 BD;  1A4S ABC;  3JZ4 CD;  3JZ4 AC;  3JZ4 BCD;  3JZ4 ABC;  1A4S ABD;  1A4S CD; 

3EK1A 3EK1B 3EK1C 3EK1D 3EK1E 3EK1F 3EK1G 3EK1H 5VBFA 5VBFB 5VBFC 5VBFD 5VBFE 5VBFF 5VBFG 5VBFH 2W8NA 5X5UA 5X5UB 5X5TA 5X5TB 3JZ4B 3JZ4C 3JZ4D 2W8PA 2W8QA 2W8RA 3RH9A 3RH9B 4V6H1 4V6H2 4V6H3 4V6H4 4V6H5 4V6H6 4V6HA 4V6HB 4V6HC 4V6HD 4V6HE 4V6HF 4V6HG 4V6HH 4V6HI 4V6HJ 4V6HK 4V6HL 4V6HM 4V6HN 4V6HO 4V6HP 4V6HQ 4V6HR 4V6HS 4V6HT 4V6HU 4V6HV 4V6HW 4V6HX 4V6HY 4V6HZ 2W8OA 3EK1A 3EK1B 3EK1C 3EK1D 3EK1E 3EK1F 3EK1G 3EK1H 5VBFA 5VBFB 5VBFC 5VBFD 5VBFE 5VBFF 5VBFG 5VBFH 2W8NA 5X5UA 5X5UB 5X5TA 5X5TB 3JZ4A 3JZ4C 3JZ4D 2W8PA 2W8QA 2W8RA 3RH9A 3RH9B 4V6H1 4V6H2 4V6H3 4V6H4 4V6H5 4V6H6 4V6HA 4V6HB 4V6HC 4V6HD 4V6HE 4V6HF 4V6HG 4V6HH 4V6HI 4V6HJ 4V6HK 4V6HL 4V6HM 4V6HN 4V6HO 4V6HP 4V6HQ 4V6HR 4V6HS 4V6HT 4V6HU 4V6HV 4V6HW 4V6HX 4V6HY 4V6HZ 2W8OA
similar chains in the pdb database (40% sequence similarity)

 
            
               
               
           
#similar chains in the pdb database (40% sequence similarity)
 3EK1_A;  3EK1_B;  3EK1_C;  3EK1_D;  3EK1_E;  3EK1_F;  3EK1_G;  3EK1_H;  5VBF_A;  5VBF_B;  5VBF_C;  5VBF_D;  5VBF_E;  5VBF_F;  5VBF_G;  5VBF_H;  2W8N_A;  5X5U_A;  5X5U_B;  5X5T_A;  5X5T_B;  3JZ4_B;  3JZ4_C;  3JZ4_D;  2W8P_A;  2W8Q_A;  2W8R_A;  3RH9_A;  3RH9_B;  4V6H_1;  4V6H_2;  4V6H_3;  4V6H_4;  4V6H_5;  4V6H_6;  4V6H_A;  4V6H_B;  4V6H_C;  4V6H_D;  4V6H_E;  4V6H_F;  4V6H_G;  4V6H_H;  4V6H_I;  4V6H_J;  4V6H_K;  4V6H_L;  4V6H_M;  4V6H_N;  4V6H_O;  4V6H_P;  4V6H_Q;  4V6H_R;  4V6H_S;  4V6H_T;  4V6H_U;  4V6H_V;  4V6H_W;  4V6H_X;  4V6H_Y;  4V6H_Z;  2W8O_A;  3EK1_A;  3EK1_B;  3EK1_C;  3EK1_D;  3EK1_E;  3EK1_F;  3EK1_G;  3EK1_H;  5VBF_A;  5VBF_B;  5VBF_C;  5VBF_D;  5VBF_E;  5VBF_F;  5VBF_G;  5VBF_H;  2W8N_A;  5X5U_A;  5X5U_B;  5X5T_A;  5X5T_B;  3JZ4_A;  3JZ4_C;  3JZ4_D;  2W8P_A;  2W8Q_A;  2W8R_A;  3RH9_A;  3RH9_B;  4V6H_1;  4V6H_2;  4V6H_3;  4V6H_4;  4V6H_5;  4V6H_6;  4V6H_A;  4V6H_B;  4V6H_C;  4V6H_D;  4V6H_E;  4V6H_F;  4V6H_G;  4V6H_H;  4V6H_I;  4V6H_J;  4V6H_K;  4V6H_L;  4V6H_M;  4V6H_N;  4V6H_O;  4V6H_P;  4V6H_Q;  4V6H_R;  4V6H_S;  4V6H_T;  4V6H_U;  4V6H_V;  4V6H_W;  4V6H_X;  4V6H_Y;  4V6H_Z;  2W8O_A; 
           

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