3HJWABC

Structure of a functional ribonucleoprotein pseudouridine synthase bound to a substrate rna
Link type Probability Chain A piercings Chain B piercings Chain C piercings
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Unlink Unlink 46% -113C +176C +283C -338C
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Interpreting sequences
Chain A Sequence
RILPADIKREVLIKDENAETNPDWGFPPEKRPIEMHIQFGVINLDKPPGPTSHEVVAWIKKILNLEKAGHGGTLDPKVSGVLPVALEKATRVVQALLPAGKEYVALMHLHGDVPEDKIIQVMKEFEGEIIQRPPLRSAVKRRLRTRKVYYIEVLEIEGRDVLFRVGVEAGTYIRSLIHHIGLALGVGAHMSELRRTRSGPFKEDETLITLHDLVDYYYFWKEDGIEEYFRKAIQPMEKAVEHLPKVWIKDSAVAAVTHGADLAVPGIAKLHAGIKRGDLVAIMTLKDELVALGKAMMTSQEMLEKTKGIAVDVEKVFMPRDWYPKLW
Chain A Sequence
FRIRKCPKCGRYTLKEVCPVCGEKTKVAHPPRFSPEDPYGEYRRRWKREVLGI
Chain A Sequence
KPSYVKFEVPKELAEKALQAVEIARDTGKIRKGTNETTKAVERGQAKLVIIAEDVDPEEIVAHLPPLCEEKEIPYIYVPSKKELGAAAGIEVAAASVAIIEPGKARDLVEEIAMKVKELM
sequence length 327,53,120
structure length 327,53,120
publication title Structure of a functional ribonucleoprotein pseudouridine synthase bound to a substrate RNA
pubmed doi rcsb
molecule tags Isomerase/rna
molecule keywords Pseudouridine synthase Cbf5
source organism Pyrococcus furiosus
ec nomenclature ec 5.4.99.25: tRNA pseudouridine(55) synthase.
pdb deposition date2009-05-22
LinkProt deposition date2016-08-17

pfam database annotations

chain Pfam Accession CodePfam Family IdentifierPfam Description
ABC PF01472 PUAPUA domain
ABC PF01509 TruB_NTruB family pseudouridylate synthase (N terminal domain)
ABC PF08068 DKCLDDKCLD (NUC011) domain
ABC PF16198 TruB_C_2tRNA pseudouridylate synthase B C-terminal domain
ABC PF04135 Nop10pNucleolar RNA-binding protein, Nop10p family
ABC PF01248 Ribosomal_L7AeRibosomal protein L7Ae/L30e/S12e/Gadd45 family
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.30.2350.10 Alpha Beta 2-Layer Sandwich Pseudouridine synthase Pseudouridine synthase 3hjwA02
3.30.1330.30 Alpha Beta 2-Layer Sandwich 60s Ribosomal Protein L30; Chain: A; 60s Ribosomal Protein L30; Chain: A; 3hjwC00
3HJYAB 3HJWAB 3HJWABC 3HJWBC
chains in the LinkProt database with same CATH superfamily
1VH8CF 1VH8AB 1VH8CDE 3HJWBC 1VH8ACDE 1VH8AC 1VH8BCDF 1VH8DE 1VH8CDEF 1VH8BC 3HJYAB 1VH8ACDF 1W5FAB 1VH8BCF 1VH8ACE 1VH8ACEF 1VH8CEF 1VH8ABCF 1VH8BCE 1VH8BCEF 3HJWABC 1VH8EF 1VH8DEF 1VH8ACF 1VH8BCDE 1VH8CE 1VH8ABCE 1VH8CDF 1VH8DF 1VH8ABC 3HJWAB
chains in the LinkProt database with same CATH topology
1VH8CF 1VH8AB 1VH8CDE 3HJWBC 1VH8ACDE 1VH8AC 1VH8BCDF 1VH8DE 1VH8CDEF 1VH8BC 3HJYAB 1VH8ACDF 1W5FAB 1VH8BCF 1VH8ACE 1VH8ACEF 1VH8CEF 1VH8ABCF 1VH8BCE 1VH8BCEF 3HJWABC 1VH8EF 1VH8DEF 1VH8ACF 1VH8BCDE 1VH8CE 1VH8ABCE 1VH8CDF 1VH8DF 1VH8ABC 3HJWAB
chains in the LinkProt database with same CATH homology


 
#chains in the LinkProt database with same CATH superfamily
 3HJY AB;  3HJW AB;  3HJW ABC;  3HJW BC; 
#chains in the LinkProt database with same CATH topology
 1VH8 CF;  1VH8 AB;  1VH8 CDE;  3HJW BC;  1VH8 ACDE;  1VH8 AC;  1VH8 BCDF;  1VH8 DE;  1VH8 CDEF;  1VH8 BC;  3HJY AB;  1VH8 ACDF;  1W5F AB;  1VH8 BCF;  1VH8 ACE;  1VH8 ACEF;  1VH8 CEF;  1VH8 ABCF;  1VH8 BCE;  1VH8 BCEF;  3HJW ABC;  1VH8 EF;  1VH8 DEF;  1VH8 ACF;  1VH8 BCDE;  1VH8 CE;  1VH8 ABCE;  1VH8 CDF;  1VH8 DF;  1VH8 ABC;  3HJW AB; 
#chains in the LinkProt database with same CATH homology
 1VH8 CF;  1VH8 AB;  1VH8 CDE;  3HJW BC;  1VH8 ACDE;  1VH8 AC;  1VH8 BCDF;  1VH8 DE;  1VH8 CDEF;  1VH8 BC;  3HJY AB;  1VH8 ACDF;  1W5F AB;  1VH8 BCF;  1VH8 ACE;  1VH8 ACEF;  1VH8 CEF;  1VH8 ABCF;  1VH8 BCE;  1VH8 BCEF;  3HJW ABC;  1VH8 EF;  1VH8 DEF;  1VH8 ACF;  1VH8 BCDE;  1VH8 CE;  1VH8 ABCE;  1VH8 CDF;  1VH8 DF;  1VH8 ABC;  3HJW AB; 
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#similar chains in the LinkProt database (?% sequence similarity)
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LinkProt | Interdisciplinary Laboratory of Biological Systems Modelling