3GGV | LinkProt

Link data interpretation

		Probability	Chain A piercings
view details	Hopf.2 U Ring	50%	-99B -100D
view details	Hopf.2 U Ring	50%	-99B -100D
view details	Hopf.2 U Ring	50%	-99B -100D
view details	Hopf.2 U Ring	50%	-99B -100D
view details	Hopf.2 U Ring	50%	-99B -100D
view details	Hopf.2 U Ring	50%	-99B -100D
view details	Hopf.2 U Ring	50%	-99B -100D
view details	Hopf.2 U Ring	50%	-99B -100D
view details	Hopf.2 U Ring	50%	-99B -100D
view details	Hopf.2 U Ring	50%	-99B -100D
view details	Hopf.2 U Ring	50%	-99B -100D
view details	Hopf.2 U Ring	50%	-99B -100D

Chain A Sequence	PQITLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYDQILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
Chain A Sequence	PQITLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYDQILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
Chain A Sequence	PQITLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYDQILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF

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sequence length	99,99,99
structure length	99,99,99
publication title	2-Pyridyl P1'-substituted symmetry-based human immunodeficiency virus protease inhibitors (A-792611 and A-790742) with potential for convenient dosing and reduced side effects. pubmed doi rcsb
molecule tags	Hydrolase
molecule keywords	V-1 protease
source organism	Human immunodeficiency virus 1
ec nomenclature	ec 2.7.7.49: RNA-directed DNA polymerase. ec 2.7.7.7: DNA-directed DNA polymerase. ec 3.1.13.2: Exoribonuclease H. ec 3.1.26.13: Retroviral ribonuclease H. ec 3.4.23.16: HIV-1 retropepsin. ec 2.7.7.49: RNA-directed DNA polymerase. ec 2.7.7.7: DNA-directed DNA polymerase. ec 3.1.13.2: Exoribonuclease H. ec 3.1.26.13: Retroviral ribonuclease H. ec 3.4.23.16: HIV-1 retropepsin. ec 2.7.7.49: RNA-directed DNA polymerase. ec 2.7.7.7: DNA-directed DNA polymerase. ec 3.1.13.2: Exoribonuclease H. ec 3.1.26.13: Retroviral ribonuclease H. ec 3.4.23.16: HIV-1 retropepsin.
pdb deposition date	2009-03-02
LinkProt deposition date	2016-08-17

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
ABD	PF00077	RVP	Retroviral aspartyl protease
ABD	PF00077	RVP	Retroviral aspartyl protease
ABD	PF00077	RVP	Retroviral aspartyl protease

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
2.40.70.10	Mainly Beta	Beta Barrel	Cathepsin D, subunit A; domain 1	Acid Proteases	3ggvA00
2.40.70.10	Mainly Beta	Beta Barrel	Cathepsin D, subunit A; domain 1	Acid Proteases	3ggvB00
2.40.70.10	Mainly Beta	Beta Barrel	Cathepsin D, subunit A; domain 1	Acid Proteases	3ggvD00

3HAUAB 3EKXAB 3GGVDGH 1A8KBDE 3FV3EFN 3GGACD 3EL1AB 3FV3BDJ 3GGXCDG 1A94BDE 3GGXCGH 3EM4UV 3FV3AGI 3FV3CHK 3EM4AU 3GGXAB 3GGVABH 3GGXEF 3DOXAQ 3GGXACD 3FV3DL 3GGVABE 1A8KDE 3GGXBCD 3JW2AB 3ECGAB 3FV3BEM 3EKPCD 1A30AC 3GGVAB 3EKTABD 3GGACGH 3GI0AC 3FV3HNP 3FV3ADL 3GI5AB 3GGAABD 3GGXFGH 3IXOAB 1AIDAB 3GGABCD 1A94DE 3EM4AB 3HAWAB 3GGXABG 3EKQAB 3FV3BGJ 3GGVEFH 3GGXABH 3GGVFGH 3FV3CIK 3GGVCDE 3HDKAB 3FV3DEF 3GGXEFH 3GGVGH 3FV3GO 3GGXDEF 3DOXAPQ 3GGXCEF 3GGACDG 3FV3CEF 3GGAAGH 3FV3CK 3FV3DEL 3FV3EFH 3GGXBEF 3GGXCDF 3GGVAGH 3EM4BUV 3GGAAB 3EKTAB 1A94ABD 3FV3CGO 3FV3BJL 3FV3EJM 3EM6AB 3FV3DLO 3FV3FHN 3GGVABD 3GGAACD 3EKPBCD 3FV3CFK 3FV3ABJ 3GGXAEF 3FV3BDL 3GGXCDE 3FV3EHP 3FV3EMN 3GGXEGH 3GGVBCD 3GGVDEF 3JVYAB 3GGVABG 3GI6AB 3FV3GHO 3EC0AB 3FV3ACK 3FV3FIN 3EKPACD 3GGXCDH 3GGVGHI 3GGXABF 3GGXDGH 3GGVEFG 3GGACDH 3FV3DFL 3EL9AB 1AJVAB 3FV3BJ 3EL4AB 3FV3FGN 3EM3AB 3FV3BCJ 3EKYAB 1A8KADE 3DOXAP 3FV3EM 3FV3BHJ 3GGXAGH 3GGXABE 3GGXBGH 3GGXGH 1A8KAB 3FV3CDK 3FV3AGO 3GGUAB 3HBOAB 3FV3AI 1A94AB 3GGAGH 3GGVCEF 3FV3DEM 3GGVCDG 3EMYAB 3FV3BHP 3FV3AEI 3H5BAB 3GGVEF 3JVWAB 3EKVAB 3GI4AB 3GGVEGH 3FV3GHP 3FV3BFJ 3GGVCD 3FV3BJO 3EKTBCD 3FV3CKN 3GGABGH 3GGVAEF 3FV3ADI 3GGVABC 3DK1AB 3EM4ABU 3FX5AB 3EKPABC 3FV3CHP 3EL0AB 3GGAABG 3FV3AEM 3EM4ABV 3EKWAB 3FV3AFI 3GGADGH 3FV3DHL 3GGVABI 1A94ADE 3GGVABF 3FV3CEK 3GGVCDH 3FV3EGO 3GGVCDI 3EKPABD 3FV3EF 3GGAABH 1A30AB 1A8KABE 3FV3DGO 3EKTABC 3GGVACD 3FV3AFN 3FV3FGO 3FV3HP 3FV3BCK 3FV3AHI 3GGVCGH 3FV3ACI 3FV3CFN 3FV3CKP 1AJXAB 3EKPAB 3GGXABD 1A30ABC 3GGVEFI 1AAQAB 3EKTCD 3FV3BGO 3FV3DGL 3FV3DFN 1A30BC 3FV3ABI 3FV3AHP 1A9MAB 3FV3CEM 3GGVCDF 3EM4AUV 3GGVBGH 1A8KABD 3FV3BDG 3GGAABC 3FV3EGM 3FV3EHM 3GGVBEF 1A8GAB 3GGXABC 3EKTACD 3FV3ABG 3GGXEFG 3GGXCD 3EL5AB 1A94ABE 3FV3EFM 3FV3FN
chains in the LinkProt database with same CATH superfamily

#chains in the LinkProt database with same CATH superfamily
 3HAU AB;  3EKX AB;  3GGV DGH;  1A8K BDE;  3FV3 EFN;  3GGA CD;  3EL1 AB;  3FV3 BDJ;  3GGX CDG;  1A94 BDE;  3GGX CGH;  3EM4 UV;  3FV3 AGI;  3FV3 CHK;  3EM4 AU;  3GGX AB;  3GGV ABH;  3GGX EF;  3DOX AQ;  3GGX ACD;  3FV3 DL;  3GGV ABE;  1A8K DE;  3GGX BCD;  3JW2 AB;  3ECG AB;  3FV3 BEM;  3EKP CD;  1A30 AC;  3GGV AB;  3EKT ABD;  3GGA CGH;  3GI0 AC;  3FV3 HNP;  3FV3 ADL;  3GI5 AB;  3GGA ABD;  3GGX FGH;  3IXO AB;  1AID AB;  3GGA BCD;  1A94 DE;  3EM4 AB;  3HAW AB;  3GGX ABG;  3EKQ AB;  3FV3 BGJ;  3GGV EFH;  3GGX ABH;  3GGV FGH;  3FV3 CIK;  3GGV CDE;  3HDK AB;  3FV3 DEF;  3GGX EFH;  3GGV GH;  3FV3 GO;  3GGX DEF;  3DOX APQ;  3GGX CEF;  3GGA CDG;  3FV3 CEF;  3GGA AGH;  3FV3 CK;  3FV3 DEL;  3FV3 EFH;  3GGX BEF;  3GGX CDF;  3GGV AGH;  3EM4 BUV;  3GGA AB;  3EKT AB;  1A94 ABD;  3FV3 CGO;  3FV3 BJL;  3FV3 EJM;  3EM6 AB;  3FV3 DLO;  3FV3 FHN;  3GGV ABD;  3GGA ACD;  3EKP BCD;  3FV3 CFK;  3FV3 ABJ;  3GGX AEF;  3FV3 BDL;  3GGX CDE;  3FV3 EHP;  3FV3 EMN;  3GGX EGH;  3GGV BCD;  3GGV DEF;  3JVY AB;  3GGV ABG;  3GI6 AB;  3FV3 GHO;  3EC0 AB;  3FV3 ACK;  3FV3 FIN;  3EKP ACD;  3GGX CDH;  3GGV GHI;  3GGX ABF;  3GGX DGH;  3GGV EFG;  3GGA CDH;  3FV3 DFL;  3EL9 AB;  1AJV AB;  3FV3 BJ;  3EL4 AB;  3FV3 FGN;  3EM3 AB;  3FV3 BCJ;  3EKY AB;  1A8K ADE;  3DOX AP;  3FV3 EM;  3FV3 BHJ;  3GGX AGH;  3GGX ABE;  3GGX BGH;  3GGX GH;  1A8K AB;  3FV3 CDK;  3FV3 AGO;  3GGU AB;  3HBO AB;  3FV3 AI;  1A94 AB;  3GGA GH;  3GGV CEF;  3FV3 DEM;  3GGV CDG;  3EMY AB;  3FV3 BHP;  3FV3 AEI;  3H5B AB;  3GGV EF;  3JVW AB;  3EKV AB;  3GI4 AB;  3GGV EGH;  3FV3 GHP;  3FV3 BFJ;  3GGV CD;  3FV3 BJO;  3EKT BCD;  3FV3 CKN;  3GGA BGH;  3GGV AEF;  3FV3 ADI;  3GGV ABC;  3DK1 AB;  3EM4 ABU;  3FX5 AB;  3EKP ABC;  3FV3 CHP;  3EL0 AB;  3GGA ABG;  3FV3 AEM;  3EM4 ABV;  3EKW AB;  3FV3 AFI;  3GGA DGH;  3FV3 DHL;  3GGV ABI;  1A94 ADE;  3GGV ABF;  3FV3 CEK;  3GGV CDH;  3FV3 EGO;  3GGV CDI;  3EKP ABD;  3FV3 EF;  3GGA ABH;  1A30 AB;  1A8K ABE;  3FV3 DGO;  3EKT ABC;  3GGV ACD;  3FV3 AFN;  3FV3 FGO;  3FV3 HP;  3FV3 BCK;  3FV3 AHI;  3GGV CGH;  3FV3 ACI;  3FV3 CFN;  3FV3 CKP;  1AJX AB;  3EKP AB;  3GGX ABD;  1A30 ABC;  3GGV EFI;  1AAQ AB;  3EKT CD;  3FV3 BGO;  3FV3 DGL;  3FV3 DFN;  1A30 BC;  3FV3 ABI;  3FV3 AHP;  1A9M AB;  3FV3 CEM;  3GGV CDF;  3EM4 AUV;  3GGV BGH;  1A8K ABD;  3FV3 BDG;  3GGA ABC;  3FV3 EGM;  3FV3 EHM;  3GGV BEF;  1A8G AB;  3GGX ABC;  3EKT ACD;  3FV3 ABG;  3GGX EFG;  3GGX CD;  3EL5 AB;  1A94 ABE;  3FV3 EFM;  3FV3 FN; 
#chains in the LinkProt database with same CATH topology
 3HAU AB;  3EKX AB;  3GGV DGH;  1A8K BDE;  3FV3 EFN;  3GGA CD;  3EL1 AB;  3FV3 BDJ;  3GGX CDG;  1A94 BDE;  3GGX CGH;  3EM4 UV;  3FV3 AGI;  3FV3 CHK;  3EM4 AU;  3GGX AB;  3GGV ABH;  3GGX EF;  3DOX AQ;  3GGX ACD;  3FV3 DL;  3GGV ABE;  1A8K DE;  3GGX BCD;  3JW2 AB;  3ECG AB;  3FV3 BEM;  3EKP CD;  1A30 AC;  3GGV AB;  3EKT ABD;  3GGA CGH;  3GI0 AC;  3FV3 HNP;  3FV3 ADL;  3GI5 AB;  3GGA ABD;  3GGX FGH;  3IXO AB;  1AID AB;  3GGA BCD;  1A94 DE;  3EM4 AB;  3HAW AB;  3GGX ABG;  3EKQ AB;  3FV3 BGJ;  3GGV EFH;  3GGX ABH;  3GGV FGH;  3FV3 CIK;  3GGV CDE;  3HDK AB;  3FV3 DEF;  3GGX EFH;  3GGV GH;  3FV3 GO;  3GGX DEF;  3DOX APQ;  3GGX CEF;  3GGA CDG;  3FV3 CEF;  3GGA AGH;  3FV3 CK;  3FV3 DEL;  3FV3 EFH;  3GGX BEF;  3GGX CDF;  3GGV AGH;  3EM4 BUV;  3GGA AB;  3EKT AB;  1A94 ABD;  3FV3 CGO;  3FV3 BJL;  3FV3 EJM;  3EM6 AB;  3FV3 DLO;  3FV3 FHN;  3GGV ABD;  3GGA ACD;  3EKP BCD;  3FV3 CFK;  3FV3 ABJ;  3GGX AEF;  3FV3 BDL;  3GGX CDE;  3FV3 EHP;  3FV3 EMN;  3GGX EGH;  3GGV BCD;  3GGV DEF;  3JVY AB;  3GGV ABG;  3GI6 AB;  3FV3 GHO;  3EC0 AB;  3FV3 ACK;  3FV3 FIN;  3EKP ACD;  3GGX CDH;  3GGV GHI;  3GGX ABF;  3GGX DGH;  3GGV EFG;  3GGA CDH;  3FV3 DFL;  3EL9 AB;  1AJV AB;  3FV3 BJ;  3EL4 AB;  3FV3 FGN;  3EM3 AB;  3FV3 BCJ;  3EKY AB;  1A8K ADE;  3DOX AP;  3FV3 EM;  3FV3 BHJ;  3GGX AGH;  3GGX ABE;  3GGX BGH;  3GGX GH;  1A8K AB;  3FV3 CDK;  3FV3 AGO;  3GGU AB;  3HBO AB;  3FV3 AI;  1A94 AB;  3GGA GH;  3GGV CEF;  3FV3 DEM;  3GGV CDG;  3EMY AB;  3FV3 BHP;  3FV3 AEI;  3H5B AB;  3GGV EF;  3JVW AB;  3EKV AB;  3GI4 AB;  3GGV EGH;  3FV3 GHP;  3FV3 BFJ;  3GGV CD;  3FV3 BJO;  3EKT BCD;  3FV3 CKN;  3GGA BGH;  3GGV AEF;  3FV3 ADI;  3GGV ABC;  3DK1 AB;  3EM4 ABU;  3FX5 AB;  3EKP ABC;  3FV3 CHP;  3EL0 AB;  3GGA ABG;  3FV3 AEM;  3EM4 ABV;  3EKW AB;  3FV3 AFI;  3GGA DGH;  3FV3 DHL;  3GGV ABI;  1A94 ADE;  3GGV ABF;  3FV3 CEK;  3GGV CDH;  3FV3 EGO;  3GGV CDI;  3EKP ABD;  3FV3 EF;  3GGA ABH;  1A30 AB;  1A8K ABE;  3FV3 DGO;  3EKT ABC;  3GGV ACD;  3FV3 AFN;  3FV3 FGO;  3FV3 HP;  3FV3 BCK;  3FV3 AHI;  3GGV CGH;  3FV3 ACI;  3FV3 CFN;  3FV3 CKP;  1AJX AB;  3EKP AB;  3GGX ABD;  1A30 ABC;  3GGV EFI;  1AAQ AB;  3EKT CD;  3FV3 BGO;  3FV3 DGL;  3FV3 DFN;  1A30 BC;  3FV3 ABI;  3FV3 AHP;  1A9M AB;  3FV3 CEM;  3GGV CDF;  3EM4 AUV;  3GGV BGH;  1A8K ABD;  3FV3 BDG;  3GGA ABC;  3FV3 EGM;  3FV3 EHM;  3GGV BEF;  1A8G AB;  3GGX ABC;  3EKT ACD;  3FV3 ABG;  3GGX EFG;  3GGX CD;  3EL5 AB;  1A94 ABE;  3FV3 EFM;  3FV3 FN; 
#chains in the LinkProt database with same CATH homology
 3HAU AB;  3EKX AB;  3GGV DGH;  1A8K BDE;  3FV3 EFN;  3GGA CD;  3EL1 AB;  3FV3 BDJ;  3GGX CDG;  1A94 BDE;  3GGX CGH;  3EM4 UV;  3FV3 AGI;  3FV3 CHK;  3EM4 AU;  3GGX AB;  3GGV ABH;  3GGX EF;  3DOX AQ;  3GGX ACD;  3FV3 DL;  3GGV ABE;  1A8K DE;  3GGX BCD;  3JW2 AB;  3ECG AB;  3FV3 BEM;  3EKP CD;  1A30 AC;  3GGV AB;  3EKT ABD;  3GGA CGH;  3GI0 AC;  3FV3 HNP;  3FV3 ADL;  3GI5 AB;  3GGA ABD;  3GGX FGH;  3IXO AB;  1AID AB;  3GGA BCD;  1A94 DE;  3EM4 AB;  3HAW AB;  3GGX ABG;  3EKQ AB;  3FV3 BGJ;  3GGV EFH;  3GGX ABH;  3GGV FGH;  3FV3 CIK;  3GGV CDE;  3HDK AB;  3FV3 DEF;  3GGX EFH;  3GGV GH;  3FV3 GO;  3GGX DEF;  3DOX APQ;  3GGX CEF;  3GGA CDG;  3FV3 CEF;  3GGA AGH;  3FV3 CK;  3FV3 DEL;  3FV3 EFH;  3GGX BEF;  3GGX CDF;  3GGV AGH;  3EM4 BUV;  3GGA AB;  3EKT AB;  1A94 ABD;  3FV3 CGO;  3FV3 BJL;  3FV3 EJM;  3EM6 AB;  3FV3 DLO;  3FV3 FHN;  3GGV ABD;  3GGA ACD;  3EKP BCD;  3FV3 CFK;  3FV3 ABJ;  3GGX AEF;  3FV3 BDL;  3GGX CDE;  3FV3 EHP;  3FV3 EMN;  3GGX EGH;  3GGV BCD;  3GGV DEF;  3JVY AB;  3GGV ABG;  3GI6 AB;  3FV3 GHO;  3EC0 AB;  3FV3 ACK;  3FV3 FIN;  3EKP ACD;  3GGX CDH;  3GGV GHI;  3GGX ABF;  3GGX DGH;  3GGV EFG;  3GGA CDH;  3FV3 DFL;  3EL9 AB;  1AJV AB;  3FV3 BJ;  3EL4 AB;  3FV3 FGN;  3EM3 AB;  3FV3 BCJ;  3EKY AB;  1A8K ADE;  3DOX AP;  3FV3 EM;  3FV3 BHJ;  3GGX AGH;  3GGX ABE;  3GGX BGH;  3GGX GH;  1A8K AB;  3FV3 CDK;  3FV3 AGO;  3GGU AB;  3HBO AB;  3FV3 AI;  1A94 AB;  3GGA GH;  3GGV CEF;  3FV3 DEM;  3GGV CDG;  3EMY AB;  3FV3 BHP;  3FV3 AEI;  3H5B AB;  3GGV EF;  3JVW AB;  3EKV AB;  3GI4 AB;  3GGV EGH;  3FV3 GHP;  3FV3 BFJ;  3GGV CD;  3FV3 BJO;  3EKT BCD;  3FV3 CKN;  3GGA BGH;  3GGV AEF;  3FV3 ADI;  3GGV ABC;  3DK1 AB;  3EM4 ABU;  3FX5 AB;  3EKP ABC;  3FV3 CHP;  3EL0 AB;  3GGA ABG;  3FV3 AEM;  3EM4 ABV;  3EKW AB;  3FV3 AFI;  3GGA DGH;  3FV3 DHL;  3GGV ABI;  1A94 ADE;  3GGV ABF;  3FV3 CEK;  3GGV CDH;  3FV3 EGO;  3GGV CDI;  3EKP ABD;  3FV3 EF;  3GGA ABH;  1A30 AB;  1A8K ABE;  3FV3 DGO;  3EKT ABC;  3GGV ACD;  3FV3 AFN;  3FV3 FGO;  3FV3 HP;  3FV3 BCK;  3FV3 AHI;  3GGV CGH;  3FV3 ACI;  3FV3 CFN;  3FV3 CKP;  1AJX AB;  3EKP AB;  3GGX ABD;  1A30 ABC;  3GGV EFI;  1AAQ AB;  3EKT CD;  3FV3 BGO;  3FV3 DGL;  3FV3 DFN;  1A30 BC;  3FV3 ABI;  3FV3 AHP;  1A9M AB;  3FV3 CEM;  3GGV CDF;  3EM4 AUV;  3GGV BGH;  1A8K ABD;  3FV3 BDG;  3GGA ABC;  3FV3 EGM;  3FV3 EHM;  3GGV BEF;  1A8G AB;  3GGX ABC;  3EKT ACD;  3FV3 ABG;  3GGX EFG;  3GGX CD;  3EL5 AB;  1A94 ABE;  3FV3 EFM;  3FV3 FN;

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#similar chains in the LinkProt database (?% sequence similarity)
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3GGVABD

Chain A Sequence

Chain A Sequence

Chain A Sequence

pfam database annotations