1AJCAB

Three-dimensional structure of the d153g mutant of e. coli alkaline phosphatase: a mutant with weaker magnesium binding and increased catalytic activity
A: 404-408
Link type Probability Chain A piercings Chain B piercings
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Unlink Unlink 43% -8B +25B -36B +449B
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Unlink Unlink 43% -8B +25B -36B +449B
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Unlink Unlink 43% -8B +25B -36B +449B
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Unlink Unlink 43% -8B +25B -36B +449B
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Unlink Unlink 43% -8B +25B -36B +449B
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Unlink Unlink 43% -8B +25B -36B +449B
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Unlink Unlink 43% -8B +25B -36B +449B
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Unlink Unlink 43% -8B +25B -36B +449B
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Unlink Unlink 43% -8B +25B -36B +449B
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Unlink Unlink 43% -8B +25B -36B +449B
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Unlink Unlink 43% -8B +25B -36B +449B
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Unlink Unlink 43% -8B +25B -36B +449B
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Unlink Unlink 43% -8B +25B -36B +449B
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Unlink Unlink 43% -8B +25B -36B +449B
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Unlink Unlink 43% -8B +25B -36B +449B
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Unlink Unlink 43% -8B +25B -36B +449B
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Unlink Unlink 43% -8B +25B -36B +449B
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Unlink Unlink 43% -8B +25B -36B +449B
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Unlink Unlink 43% -8B +25B -36B +449B
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Unlink Unlink 43% -8B +25B -36B +449B
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Unlink Unlink 43% -8B +25B -36B +449B
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Interpreting sequences
Chain A Sequence
TPEMPVLENRAAQGDITAPGGARRLTGDQTAALRDSLSDKPAKNIILLIGDGMGDSEITAARNYAEGAGGFFKGIDALPLTGQYTHYALNKKTGKPDYVTDSAASATAWSTGVKTYNGALGVDIHEKDHPTILEMAKAAGLATGNVSTAELQGATPAALVAHVTSRKCYGPSATSEKCPGNALEKGGKGSITEQLLNARADVTLGGGAKTFAETATAGEWQGKTLREQAEARGYQLVSDAASLNSVTEANQQKPLLGLFADGNMPVRWLGPKATYHGNIDKPAVTCTPNPQRNDSVPTLAQMTDKAIELLSKNEKGFFLQVEGASIDKQDHAANPCGQIGETVDLDEAVQRALEFAKKEGNTLVIVTADHAHASQIVAPDTKAPGLTQALNTKDGAVMVMSYGN---DSQEHTGSQLRIAAYGPHAANVVGLTDQTDLFYTMKAALGLK
Chain A Sequence
TPEMPVLENRAAQGDITAPGGARRLTGDQTAALRDSLSDKPAKNIILLIGDGMGDSEITAARNYAEGAGGFFKGIDALPLTGQYTHYALNKKTGKPDYVTDSAASATAWSTGVKTYNGALGVDIHEKDHPTILEMAKAAGLATGNVSTAELQGATPAALVAHVTSRKCYGPSATSEKCPGNALEKGGKGSITEQLLNARADVTLGGGAKTFAETATAGEWQGKTLREQAEARGYQLVSDAASLNSVTEANQQKPLLGLFADGNMPVRWLGPKATYHGNIDKPAVTCTPNPQRNDSVPTLAQMTDKAIELLSKNEKGFFLQVEGASIDKQDHAANPCGQIGETVDLDEAVQRALEFAKKEGNTLVIVTADHAHASQIVAPDTKAPGLTQALNTKDGAVMVMSYGNSEEDSQEHTGSQLRIAAYGPHAANVVGLTDQTDLFYTMKAALGLK
sequence length 449,449
structure length 446,449
publication title Crystallographic analysis of reversible metal binding observed in a mutant (Asp153-->Gly) of Escherichia coli alkaline phosphatase.
pubmed doi rcsb
molecule tags Non specific mono-esterase
molecule keywords ALKALINE PHOSPHATASE
source organism Escherichia coli
missing residues A: 404-408
ec nomenclature ec 3.1.3.1: Alkaline phosphatase.
ec 3.1.3.1: Alkaline phosphatase.
pdb deposition date1995-07-18
LinkProt deposition date2016-08-17

pfam database annotations

chain Pfam Accession CodePfam Family IdentifierPfam Description
AB PF00245 Alk_phosphataseAlkaline phosphatase
AB PF00245 Alk_phosphataseAlkaline phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 1ajcA00
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 1ajcB00
1AJBAB 1AJDAB 1ANJAB 1AJAAB 1ALHAB 1AJCAB 1ANIAB
chains in the LinkProt database with same CATH superfamily
1AJBAB 1AJDAB 1ANJAB 1AJAAB 1ALHAB 1AJCAB 1ANIAB
chains in the LinkProt database with same CATH topology
1AJBAB 1AJDAB 1ANJAB 1AJAAB 1ALHAB 1AJCAB 1ANIAB
chains in the LinkProt database with same CATH homology


 
#chains in the LinkProt database with same CATH superfamily
 1AJB AB;  1AJD AB;  1ANJ AB;  1AJA AB;  1ALH AB;  1AJC AB;  1ANI AB; 
#chains in the LinkProt database with same CATH topology
 1AJB AB;  1AJD AB;  1ANJ AB;  1AJA AB;  1ALH AB;  1AJC AB;  1ANI AB; 
#chains in the LinkProt database with same CATH homology
 1AJB AB;  1AJD AB;  1ANJ AB;  1AJA AB;  1ALH AB;  1AJC AB;  1ANI AB; 
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#similar chains in the LinkProt database (?% sequence similarity)
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#similar chains, but unlinked
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#similar chains in the pdb database (?% sequence similarity)
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LinkProt | Interdisciplinary Laboratory of Biological Systems Modelling