1AJBAB

Three-dimensional structure of the d153g mutant of e. coli alkaline phosphatase: a mutant with weaker magnesium binding and increased catalytic activity
Link type Probability Chain A piercings Chain B piercings
view details
Unlink Unlink 48% -8A +24A -36A +349A -360A +450A
view details
Unlink Unlink 48% -8A +24A -36A +349A -360A +450A
view details
Unlink Unlink 48% -8A +24A -36A +349A -360A +450A
view details
Unlink Unlink 48% -8A +24A -36A +349A -360A +450A
view details
Unlink Unlink 48% -8A +24A -36A +349A -360A +450A
view details
Unlink Unlink 48% -8A +24A -36A +349A -360A +450A
view details
Unlink Unlink 48% -8A +24A -36A +349A -360A +450A
view details
Unlink Unlink 48% -8A +24A -36A +349A -360A +450A
view details
Unlink Unlink 48% -8A +24A -36A +349A -360A +450A
view details
Unlink Unlink 48% -8A +24A -36A +349A -360A +450A
view details
Unlink Unlink 48% -8A +24A -36A +349A -360A +450A
view details
Unlink Unlink 48% -8A +24A -36A +349A -360A +450A
view details
Unlink Unlink 48% -8A +24A -36A +349A -360A +450A
view details
Unlink Unlink 48% -8A +24A -36A +349A -360A +450A
view details
Unlink Unlink 48% -8A +24A -36A +349A -360A +450A
view details
Unlink Unlink 48% -8A +24A -36A +349A -360A +450A
view details
Unlink Unlink 48% -8A +24A -36A +349A -360A +450A
view details
Unlink Unlink 48% -8A +24A -36A +349A -360A +450A
view details
Unlink Unlink 48% -8A +24A -36A +349A -360A +450A
view details
Unlink Unlink 48% -8A +24A -36A +349A -360A +450A
view details
Unlink Unlink 48% -8A +24A -36A +349A -360A +450A
view details
Unlink Unlink 48% -8A +24A -36A +349A -360A +450A
view details
Unlink Unlink 48% -8A +24A -36A +349A -360A +450A
Interpreting sequences
Chain A Sequence
TPEMPVLENRAAQGDITAPGGARRLTGDQTAALRDSLSDKPAKNIILLIGDGMGDSEITAARNYAEGAGGFFKGIDALPLTGQYTHYALNKKTGKPDYVTDSAASATAWSTGVKTYNGALGVDIHEKDHPTILEMAKAAGLATGNVSTAELQGATPAALVAHVTSRKCYGPSATSEKCPGNALEKGGKGSITEQLLNARADVTLGGGAKTFAETATAGEWQGKTLREQAEARGYQLVSDAASLNSVTEANQQKPLLGLFADGNMPVRWLGPKATYHGNIDKPAVTCTPNPQRNDSVPTLAQMTDKAIELLSKNEKGFFLQVEGASIDKQDHAANPCGQIGETVDLDEAVQRALEFAKKEGNTLVIVTADHAHASQIVAPDTKAPGLTQALNTKDGAVMVMSYGNSEEDSQEHTGSQLRIAAYGPHAANVVGLTDQTDLFYTMKAALGLK
Chain A Sequence
TPEMPVLENRAAQGDITAPGGARRLTGDQTAALRDSLSDKPAKNIILLIGDGMGDSEITAARNYAEGAGGFFKGIDALPLTGQYTHYALNKKTGKPDYVTDSAASATAWSTGVKTYNGALGVDIHEKDHPTILEMAKAAGLATGNVSTAELQGATPAALVAHVTSRKCYGPSATSEKCPGNALEKGGKGSITEQLLNARADVTLGGGAKTFAETATAGEWQGKTLREQAEARGYQLVSDAASLNSVTEANQQKPLLGLFADGNMPVRWLGPKATYHGNIDKPAVTCTPNPQRNDSVPTLAQMTDKAIELLSKNEKGFFLQVEGASIDKQDHAANPCGQIGETVDLDEAVQRALEFAKKEGNTLVIVTADHAHASQIVAPDTKAPGLTQALNTKDGAVMVMSYGNSEEDSQEHTGSQLRIAAYGPHAANVVGLTDQTDLFYTMKAALGLK
sequence length 449,449
structure length 449,449
publication title 3-D structure of the D153G mutant of Escherichia coli alkaline phosphatase: an enzyme with weaker magnesium binding and increased catalytic activity.
pubmed doi rcsb
molecule tags Non specific mono-esterase
molecule keywords ALKALINE PHOSPHATASE
source organism Escherichia coli
ec nomenclature ec 3.1.3.1: Alkaline phosphatase.
ec 3.1.3.1: Alkaline phosphatase.
pdb deposition date1995-08-19
LinkProt deposition date2016-08-17

pfam database annotations

chain Pfam Accession CodePfam Family IdentifierPfam Description
AB PF00245 Alk_phosphataseAlkaline phosphatase
AB PF00245 Alk_phosphataseAlkaline phosphatase
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 1ajbA00
3.40.720.10 Alpha Beta 3-Layer(aba) Sandwich Alkaline Phosphatase, subunit A Alkaline Phosphatase, subunit A 1ajbB00
1AJBAB 1AJDAB 1ANJAB 1AJAAB 1ALHAB 1AJCAB 1ANIAB
chains in the LinkProt database with same CATH superfamily
1AJBAB 1AJDAB 1ANJAB 1AJAAB 1ALHAB 1AJCAB 1ANIAB
chains in the LinkProt database with same CATH topology
1AJBAB 1AJDAB 1ANJAB 1AJAAB 1ALHAB 1AJCAB 1ANIAB
chains in the LinkProt database with same CATH homology


 
#chains in the LinkProt database with same CATH superfamily
 1AJB AB;  1AJD AB;  1ANJ AB;  1AJA AB;  1ALH AB;  1AJC AB;  1ANI AB; 
#chains in the LinkProt database with same CATH topology
 1AJB AB;  1AJD AB;  1ANJ AB;  1AJA AB;  1ALH AB;  1AJC AB;  1ANI AB; 
#chains in the LinkProt database with same CATH homology
 1AJB AB;  1AJD AB;  1ANJ AB;  1AJA AB;  1ALH AB;  1AJC AB;  1ANI AB; 

3TG0A 3TG0B 3TG0C 3TG0D 3BDGA 3BDGB 3BDFA 3BDFB 1Y6VA 1Y6VB 3BDHA 3BDHB 1ED9A 1ED9B 1ED8A 1ED8B 1Y7AA 1Y7AB 1B8JA 1B8JB 1ALKA 1ALKB 1EW9A 1EW9B 1KH5A 1KH5B 3CMRA 3CMRB 5C66A 5C66B 2G9YA 2G9YB 1URAA 1URAB 1HQAA 1HQAB 1ALIA 1ALIB 1URBA 1URBB 2GA3A 2GA3B 1EW8A 1EW8B 1HJKA 1HJKB 1KHJA 1KHJB 3DYCA 3DYCB 5TPQA 5TPQB 1ANJA 1ANJB 1KH7A 1KH7B 1AJAA 1AJAB 1AJBB 1AJDA 1AJDB 1AJCA 1AJCB 2ANHA 2ANHB 1KH4A 1KH4B 1KHKA 1KHKB 4YR1A 4YR1B 1ELXA 1ELXB 1ANIA 1ANIB 1ELZA 1ELZB 1ALJA 1ALJB 1KHLA 1KHLB 1ELYA 1ELYB 1ALHA 1ALHB 1KH9A 1KH9B 3DPCA 3DPCB 1KHNA 1KHNB 4KM4A 4KM4B 6PSIB 5JTLE 3TG0A 3TG0B 3TG0C 3TG0D 3BDGA 3BDGB 3BDFA 3BDFB 1Y6VA 1Y6VB 3BDHA 3BDHB 1ED9A 1ED9B 1ED8A 1ED8B 1Y7AA 1Y7AB 1B8JA 1B8JB 1ALKA 1ALKB 1EW9A 1EW9B 1KH5A 1KH5B 3CMRA 3CMRB 5C66A 5C66B 2G9YA 2G9YB 1URAA 1URAB 1HQAA 1HQAB 1ALIA 1ALIB 1URBA 1URBB 2GA3A 2GA3B 1EW8A 1EW8B 1HJKA 1HJKB 1KHJA 1KHJB 3DYCA 3DYCB 5TPQA 5TPQB 1ANJA 1ANJB 1KH7A 1KH7B 1AJAA 1AJAB 1AJBA 1AJDA 1AJDB 1AJCA 1AJCB 2ANHA 2ANHB 1KH4A 1KH4B 1KHKA 1KHKB 4YR1A 4YR1B 1ELXA 1ELXB 1ANIA 1ANIB 1ELZA 1ELZB 1ALJA 1ALJB 1KHLA 1KHLB 1ELYA 1ELYB 1ALHA 1ALHB 1KH9A 1KH9B 3DPCA 3DPCB 1KHNA 1KHNB 4KM4A 4KM4B 6PSIB 5JTLE
similar chains in the pdb database (40% sequence similarity)

 
            
               
               
           
#similar chains in the pdb database (40% sequence similarity)
 3TG0_A;  3TG0_B;  3TG0_C;  3TG0_D;  3BDG_A;  3BDG_B;  3BDF_A;  3BDF_B;  1Y6V_A;  1Y6V_B;  3BDH_A;  3BDH_B;  1ED9_A;  1ED9_B;  1ED8_A;  1ED8_B;  1Y7A_A;  1Y7A_B;  1B8J_A;  1B8J_B;  1ALK_A;  1ALK_B;  1EW9_A;  1EW9_B;  1KH5_A;  1KH5_B;  3CMR_A;  3CMR_B;  5C66_A;  5C66_B;  2G9Y_A;  2G9Y_B;  1URA_A;  1URA_B;  1HQA_A;  1HQA_B;  1ALI_A;  1ALI_B;  1URB_A;  1URB_B;  2GA3_A;  2GA3_B;  1EW8_A;  1EW8_B;  1HJK_A;  1HJK_B;  1KHJ_A;  1KHJ_B;  3DYC_A;  3DYC_B;  5TPQ_A;  5TPQ_B;  1ANJ_A;  1ANJ_B;  1KH7_A;  1KH7_B;  1AJA_A;  1AJA_B;  1AJB_B;  1AJD_A;  1AJD_B;  1AJC_A;  1AJC_B;  2ANH_A;  2ANH_B;  1KH4_A;  1KH4_B;  1KHK_A;  1KHK_B;  4YR1_A;  4YR1_B;  1ELX_A;  1ELX_B;  1ANI_A;  1ANI_B;  1ELZ_A;  1ELZ_B;  1ALJ_A;  1ALJ_B;  1KHL_A;  1KHL_B;  1ELY_A;  1ELY_B;  1ALH_A;  1ALH_B;  1KH9_A;  1KH9_B;  3DPC_A;  3DPC_B;  1KHN_A;  1KHN_B;  4KM4_A;  4KM4_B;  6PSI_B;  5JTL_E;  3TG0_A;  3TG0_B;  3TG0_C;  3TG0_D;  3BDG_A;  3BDG_B;  3BDF_A;  3BDF_B;  1Y6V_A;  1Y6V_B;  3BDH_A;  3BDH_B;  1ED9_A;  1ED9_B;  1ED8_A;  1ED8_B;  1Y7A_A;  1Y7A_B;  1B8J_A;  1B8J_B;  1ALK_A;  1ALK_B;  1EW9_A;  1EW9_B;  1KH5_A;  1KH5_B;  3CMR_A;  3CMR_B;  5C66_A;  5C66_B;  2G9Y_A;  2G9Y_B;  1URA_A;  1URA_B;  1HQA_A;  1HQA_B;  1ALI_A;  1ALI_B;  1URB_A;  1URB_B;  2GA3_A;  2GA3_B;  1EW8_A;  1EW8_B;  1HJK_A;  1HJK_B;  1KHJ_A;  1KHJ_B;  3DYC_A;  3DYC_B;  5TPQ_A;  5TPQ_B;  1ANJ_A;  1ANJ_B;  1KH7_A;  1KH7_B;  1AJA_A;  1AJA_B;  1AJB_A;  1AJD_A;  1AJD_B;  1AJC_A;  1AJC_B;  2ANH_A;  2ANH_B;  1KH4_A;  1KH4_B;  1KHK_A;  1KHK_B;  4YR1_A;  4YR1_B;  1ELX_A;  1ELX_B;  1ANI_A;  1ANI_B;  1ELZ_A;  1ELZ_B;  1ALJ_A;  1ALJ_B;  1KHL_A;  1KHL_B;  1ELY_A;  1ELY_B;  1ALH_A;  1ALH_B;  1KH9_A;  1KH9_B;  3DPC_A;  3DPC_B;  1KHN_A;  1KHN_B;  4KM4_A;  4KM4_B;  6PSI_B;  5JTL_E; 
           

LinkProt | Interdisciplinary Laboratory of Biological Systems Modelling