6ZO5BCDE

Fusidic acid binding to the tm1/tm2 groove of acrb-g619p_g621p
Link type Probability Chain B piercings Chain C piercings Chain D piercings Chain E piercings
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Other Other 42% -37C +130C -179C +275C -610C -1035D -167E -167E -42B +69B -79B -720B +816B -1034B -166B -167B -26C -386C
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Other Other 42% -37C +130C -179C +275C -610C -1035D -167E -167E -42B +69B -79B -720B +816B -1034B -166B -167B -26C -386C
view details
Other Other 42% -37C +130C -179C +275C -610C -1035D -167E -167E -42B +69B -79B -720B +816B -1034B -166B -167B -26C -386C
view details
Other Other 42% -37C +130C -179C +275C -610C -1035D -167E -167E -42B +69B -79B -720B +816B -1034B -166B -167B -26C -386C
view details
Other Other 42% -37C +130C -179C +275C -610C -1035D -167E -167E -42B +69B -79B -720B +816B -1034B -166B -167B -26C -386C
view details
Other Other 42% -37C +130C -179C +275C -610C -1035D -167E -167E -42B +69B -79B -720B +816B -1034B -166B -167B -26C -386C
view details
Other Other 42% -37C +130C -179C +275C -610C -1035D -167E -167E -42B +69B -79B -720B +816B -1034B -166B -167B -26C -386C
view details
Other Other 42% -37C +130C -179C +275C -610C -1035D -167E -167E -42B +69B -79B -720B +816B -1034B -166B -167B -26C -386C
view details
Other Other 42% -37C +130C -179C +275C -610C -1035D -167E -167E -42B +69B -79B -720B +816B -1034B -166B -167B -26C -386C
view details
Other Other 42% -37C +130C -179C +275C -610C -1035D -167E -167E -42B +69B -79B -720B +816B -1034B -166B -167B -26C -386C
view details
Other Other 42% -37C +130C -179C +275C -610C -1035D -167E -167E -42B +69B -79B -720B +816B -1034B -166B -167B -26C -386C
view details
Other Other 42% -37C +130C -179C +275C -610C -1035D -167E -167E -42B +69B -79B -720B +816B -1034B -166B -167B -26C -386C
view details
Other Other 42% -37C +130C -179C +275C -610C -1035D -167E -167E -42B +69B -79B -720B +816B -1034B -166B -167B -26C -386C
view details
Other Other 42% -37C +130C -179C +275C -610C -1035D -167E -167E -42B +69B -79B -720B +816B -1034B -166B -167B -26C -386C
view details
Other Other 42% -37C +130C -179C +275C -610C -1035D -167E -167E -42B +69B -79B -720B +816B -1034B -166B -167B -26C -386C
view details
Other Other 42% -37C +130C -179C +275C -610C -1035D -167E -167E -42B +69B -79B -720B +816B -1034B -166B -167B -26C -386C
view details
Other Other 42% -37C +130C -179C +275C -610C -1035D -167E -167E -42B +69B -79B -720B +816B -1034B -166B -167B -26C -386C
view details
Other Other 42% -37C +130C -179C +275C -610C -1035D -167E -167E -42B +69B -79B -720B +816B -1034B -166B -167B -26C -386C
view details
Other Other 42% -37C +130C -179C +275C -610C -1035D -167E -167E -42B +69B -79B -720B +816B -1034B -166B -167B -26C -386C
view details
Other Other 42% -37C +130C -179C +275C -610C -1035D -167E -167E -42B +69B -79B -720B +816B -1034B -166B -167B -26C -386C
view details
Other Other 42% -37C +130C -179C +275C -610C -1035D -167E -167E -42B +69B -79B -720B +816B -1034B -166B -167B -26C -386C
view details
Other Other 42% -37C +130C -179C +275C -610C -1035D -167E -167E -42B +69B -79B -720B +816B -1034B -166B -167B -26C -386C
view details
Other Other 42% -37C +130C -179C +275C -610C -1035D -167E -167E -42B +69B -79B -720B +816B -1034B -166B -167B -26C -386C
view details
Other Other 42% -37C +130C -179C +275C -610C -1035D -167E -167E -42B +69B -79B -720B +816B -1034B -166B -167B -26C -386C
view details
Other Other 42% -37C +130C -179C +275C -610C -1035D -167E -167E -42B +69B -79B -720B +816B -1034B -166B -167B -26C -386C
view details
Other Other 42% -37C +130C -179C +275C -610C -1035D -167E -167E -42B +69B -79B -720B +816B -1034B -166B -167B -26C -386C
view details
Other Other 42% -37C +130C -179C +275C -610C -1035D -167E -167E -42B +69B -79B -720B +816B -1034B -166B -167B -26C -386C
view details
Other Other 42% -37C +130C -179C +275C -610C -1035D -167E -167E -42B +69B -79B -720B +816B -1034B -166B -167B -26C -386C
view details
Other Other 42% -37C +130C -179C +275C -610C -1035D -167E -167E -42B +69B -79B -720B +816B -1034B -166B -167B -26C -386C
view details
Other Other 42% -37C +130C -179C +275C -610C -1035D -167E -167E -42B +69B -79B -720B +816B -1034B -166B -167B -26C -386C
view details
Other Other 42% -37C +130C -179C +275C -610C -1035D -167E -167E -42B +69B -79B -720B +816B -1034B -166B -167B -26C -386C
view details
Other Other 42% -37C +130C -179C +275C -610C -1035D -167E -167E -42B +69B -79B -720B +816B -1034B -166B -167B -26C -386C
view details
Other Other 42% -37C +130C -179C +275C -610C -1035D -167E -167E -42B +69B -79B -720B +816B -1034B -166B -167B -26C -386C
view details
Other Other 42% -37C +130C -179C +275C -610C -1035D -167E -167E -42B +69B -79B -720B +816B -1034B -166B -167B -26C -386C
view details
Other Other 42% -37C +130C -179C +275C -610C -1035D -167E -167E -42B +69B -79B -720B +816B -1034B -166B -167B -26C -386C
view details
Other Other 42% -37C +130C -179C +275C -610C -1035D -167E -167E -42B +69B -79B -720B +816B -1034B -166B -167B -26C -386C
view details
Other Other 42% -37C +130C -179C +275C -610C -1035D -167E -167E -42B +69B -79B -720B +816B -1034B -166B -167B -26C -386C
view details
Other Other 42% -37C +130C -179C +275C -610C -1035D -167E -167E -42B +69B -79B -720B +816B -1034B -166B -167B -26C -386C
view details
Other Other 42% -37C +130C -179C +275C -610C -1035D -167E -167E -42B +69B -79B -720B +816B -1034B -166B -167B -26C -386C
view details
Other Other 42% -37C +130C -179C +275C -610C -1035D -167E -167E -42B +69B -79B -720B +816B -1034B -166B -167B -26C -386C
view details
Other Other 42% -37C +130C -179C +275C -610C -1035D -167E -167E -42B +69B -79B -720B +816B -1034B -166B -167B -26C -386C
view details
Other Other 42% -37C +130C -179C +275C -610C -1035D -167E -167E -42B +69B -79B -720B +816B -1034B -166B -167B -26C -386C
view details
Other Other 42% -37C +130C -179C +275C -610C -1035D -167E -167E -42B +69B -79B -720B +816B -1034B -166B -167B -26C -386C
view details
Other Other 42% -37C +130C -179C +275C -610C -1035D -167E -167E -42B +69B -79B -720B +816B -1034B -166B -167B -26C -386C
view details
Other Other 42% -37C +130C -179C +275C -610C -1035D -167E -167E -42B +69B -79B -720B +816B -1034B -166B -167B -26C -386C
view details
Other Other 42% -37C +130C -179C +275C -610C -1035D -167E -167E -42B +69B -79B -720B +816B -1034B -166B -167B -26C -386C
view details
Other Other 42% -37C +130C -179C +275C -610C -1035D -167E -167E -42B +69B -79B -720B +816B -1034B -166B -167B -26C -386C
view details
Other Other 42% -37C +130C -179C +275C -610C -1035D -167E -167E -42B +69B -79B -720B +816B -1034B -166B -167B -26C -386C
view details
Other Other 42% -37C +130C -179C +275C -610C -1035D -167E -167E -42B +69B -79B -720B +816B -1034B -166B -167B -26C -386C
view details
Other Other 42% -37C +130C -179C +275C -610C -1035D -167E -167E -42B +69B -79B -720B +816B -1034B -166B -167B -26C -386C
view details
Other Other 42% -37C +130C -179C +275C -610C -1035D -167E -167E -42B +69B -79B -720B +816B -1034B -166B -167B -26C -386C
view details
Other Other 42% -37C +130C -179C +275C -610C -1035D -167E -167E -42B +69B -79B -720B +816B -1034B -166B -167B -26C -386C
view details
Other Other 42% -37C +130C -179C +275C -610C -1035D -167E -167E -42B +69B -79B -720B +816B -1034B -166B -167B -26C -386C
Interpreting sequences
Chain B Sequence
MPNFFIDRPIFAWVIAIIIMLAGGLAILKLPVAQYPTIAPPAVTISASYPGADAKTVQDTVTQVIEQNMNGIDNLMYMSSNSDSTGTVQITLTFESGTDADIAQVQVQNKLQLAMPLLPQEVQQQGVSVEKSSSSFLMVVGVINTDGTMTQEDISDYVAANMKDAISRTSGVGDVQLFGSQYAMRIWMNPNELNKFQLTPVDVITAIKAQNAQVAAGQLGGTPPVKGQQLNASIIAQTRLTSTEEFGKILLKVNQDGSRVLLRDVAKIELGGENYDIIAEFNGQPASGLGIKLATGANALDTAAAIRAELAKMEPFFPSGLKIVYPYDTTPFVKISIHEVVKTLVEAIILVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFGMVLAIGLLVDDAIVVVENVERVMAEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMALSVLVALILTPALCATMLKPIAKGDHGEGKKGFFGWFNRMFEKSTHHYTDSVGGILRSTGRYLVLYLIIVVGMAYLFVRLPSSFLPDEDQGVFMTMVQLPAGATQERTQKVLNEVTHYYLTKEKNNVESVFAVNGFGFAPRPQNTGIAFVSLKDWADRPGEENKVEAITMRATRAFSQIKDAMVFAFNLPAIVELGTATGFDFELIDQAGLGHEKLTQARNQLLAEAAKHPDMLTSVRPNGLEDTPQFKIDIDQEKAQALGVSINDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYRMLPDDIGDWYVRAADGQMVPFSAFSSSRWEYGSPRLERYNGLPSMEILGQAAPGKSTGEAMELMEQLASKLPTGVGYDWTGMSYQERLSGNQAPSLYAISLIVVFLCLAALYESWSIPFSVMLVVPLGVIGALLAATFRGLTNDVYFQVGLLTTIGLSAKNAILIVEFAKDLMDKEGKGLIEATLDAVRMRLRPILMTSLAFILGVMPLVISTGAGSGAQNAVGTGVMGGMVTATVLAIFFVPVFFVVVRRRFS
Chain B Sequence
MPNFFIDRPIFAWVIAIIIMLAGGLAILKLPVAQYPTIAPPAVTISASYPGADAKTVQDTVTQVIEQNMNGIDNLMYMSSNSDSTGTVQITLTFESGTDADIAQVQVQNKLQLAMPLLPQEVQQQGVSVEKSSSSFLMVVGVINTDGTMTQEDISDYVAANMKDAISRTSGVGDVQLFGSQYAMRIWMNPNELNKFQLTPVDVITAIKAQNAQVAAGQLGGTPPVKGQQLNASIIAQTRLTSTEEFGKILLKVNQDGSRVLLRDVAKIELGGENYDIIAEFNGQPASGLGIKLATGANALDTAAAIRAELAKMEPFFPSGLKIVYPYDTTPFVKISIHEVVKTLVEAIILVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFGMVLAIGLLVDDAIVVVENVERVMAEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMALSVLVALILTPALCATMLKPIAKGDHGEGKKGFFGWFNRMFEKSTHHYTDSVGGILRSTGRYLVLYLIIVVGMAYLFVRLPSSFLPDEDQGVFMTMVQLPAGATQERTQKVLNEVTHYYLTKEKNNVESVFAVNGFGFAPRPQNTGIAFVSLKDWADRPGEENKVEAITMRATRAFSQIKDAMVFAFNLPAIVELGTATGFDFELIDQAGLGHEKLTQARNQLLAEAAKHPDMLTSVRPNGLEDTPQFKIDIDQEKAQALGVSINDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYRMLPDDIGDWYVRAADGQMVPFSAFSSSRWEYGSPRLERYNGLPSMEILGQAAPGKSTGEAMELMEQLASKLPTGVGYDWTGMSYQERLSGNQAPSLYAISLIVVFLCLAALYESWSIPFSVMLVVPLGVIGALLAATFRGLTNDVYFQVGLLTTIGLSAKNAILIVEFAKDLMDKEGKGLIEATLDAVRMRLRPILMTSLAFILGVMPLVISTGAGSGAQNAVGTGVMGGMVTATVLAIFFVPVFFVVVRRRFS
Chain B Sequence
SDLGKKLLEAARAGRDDEVRILMANGADVNAADVVGWTPLHLAAYWGHLEIVEVLLKNGADVNAYDTLGSTPLHLAAHFGHLEIVEVLLKNGADVNAKDDNGITPLHLAANRGHLEIVEVLLKYGADVNAQDKFGKTAFDISINNGNEDLAEILQ
Chain B Sequence
LGKKLLEAARAGRDDEVRILMANGADVNAADVVGWTPLHLAAYWGHLEIVEVLLKNGADVNAYDTLGSTPLHLAAHFGHLEIVEVLLKNGADVNAKDDNGITPLHLAANRGHLEIVEVLLKYGADVNAQDKFGKTAFDISINNGNEDLAEILQ
sequence length 1034,1034,155,153
structure length 1034,1034,155,153
publication title Fusidic acid binding to the TM1/TM2 groove of AcrB-G619P_G621P
rcsb
molecule tags Transport protein
molecule keywords Multidrug efflux pump subunit AcrB
source organism Escherichia coli k-12
pdb deposition date2020-07-07
LinkProt deposition date2021-05-22

pfam database annotations

chain Pfam Accession CodePfam Family IdentifierPfam Description
BCDE PF00873 ACR_tranAcrB/AcrD/AcrF family
BCDE PF00873 ACR_tranAcrB/AcrD/AcrF family
Image from the rcsb pdb (www.rcsb.org)
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LinkProt | Interdisciplinary Laboratory of Biological Systems Modelling