6X0PABCD

Ash1l set domain q2265a mutant in complex with as-5
Link type Probability Chain A piercings Chain B piercings Chain C piercings Chain D piercings
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Other Other 35% -2065B +2283B +2072C -2137C +2197C +2227C -2237C -2282C +2136D -2167D +2239D +2282A +2154C -2250C
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Other Other 35% -2065B +2283B +2072C -2137C +2197C +2227C -2237C -2282C +2136D -2167D +2239D +2282A +2154C -2250C
view details
Other Other 35% -2065B +2283B +2072C -2137C +2197C +2227C -2237C -2282C +2136D -2167D +2239D +2282A +2154C -2250C
view details
Other Other 35% -2065B +2283B +2072C -2137C +2197C +2227C -2237C -2282C +2136D -2167D +2239D +2282A +2154C -2250C
view details
Other Other 35% -2065B +2283B +2072C -2137C +2197C +2227C -2237C -2282C +2136D -2167D +2239D +2282A +2154C -2250C
view details
Other Other 35% -2065B +2283B +2072C -2137C +2197C +2227C -2237C -2282C +2136D -2167D +2239D +2282A +2154C -2250C
view details
Other Other 35% -2065B +2283B +2072C -2137C +2197C +2227C -2237C -2282C +2136D -2167D +2239D +2282A +2154C -2250C
view details
Other Other 35% -2065B +2283B +2072C -2137C +2197C +2227C -2237C -2282C +2136D -2167D +2239D +2282A +2154C -2250C
view details
Other Other 35% -2065B +2283B +2072C -2137C +2197C +2227C -2237C -2282C +2136D -2167D +2239D +2282A +2154C -2250C
view details
Other Other 35% -2065B +2283B +2072C -2137C +2197C +2227C -2237C -2282C +2136D -2167D +2239D +2282A +2154C -2250C
view details
Other Other 35% -2065B +2283B +2072C -2137C +2197C +2227C -2237C -2282C +2136D -2167D +2239D +2282A +2154C -2250C
view details
Other Other 35% -2065B +2283B +2072C -2137C +2197C +2227C -2237C -2282C +2136D -2167D +2239D +2282A +2154C -2250C
view details
Other Other 35% -2065B +2283B +2072C -2137C +2197C +2227C -2237C -2282C +2136D -2167D +2239D +2282A +2154C -2250C
view details
Other Other 35% -2065B +2283B +2072C -2137C +2197C +2227C -2237C -2282C +2136D -2167D +2239D +2282A +2154C -2250C
view details
Other Other 35% -2065B +2283B +2072C -2137C +2197C +2227C -2237C -2282C +2136D -2167D +2239D +2282A +2154C -2250C
view details
Other Other 35% -2065B +2283B +2072C -2137C +2197C +2227C -2237C -2282C +2136D -2167D +2239D +2282A +2154C -2250C
view details
Other Other 35% -2065B +2283B +2072C -2137C +2197C +2227C -2237C -2282C +2136D -2167D +2239D +2282A +2154C -2250C
view details
Other Other 35% -2065B +2283B +2072C -2137C +2197C +2227C -2237C -2282C +2136D -2167D +2239D +2282A +2154C -2250C
view details
Other Other 35% -2065B +2283B +2072C -2137C +2197C +2227C -2237C -2282C +2136D -2167D +2239D +2282A +2154C -2250C
view details
Other Other 35% -2065B +2283B +2072C -2137C +2197C +2227C -2237C -2282C +2136D -2167D +2239D +2282A +2154C -2250C
view details
Other Other 35% -2065B +2283B +2072C -2137C +2197C +2227C -2237C -2282C +2136D -2167D +2239D +2282A +2154C -2250C
view details
Other Other 35% -2065B +2283B +2072C -2137C +2197C +2227C -2237C -2282C +2136D -2167D +2239D +2282A +2154C -2250C
view details
Other Other 35% -2065B +2283B +2072C -2137C +2197C +2227C -2237C -2282C +2136D -2167D +2239D +2282A +2154C -2250C
view details
Other Other 35% -2065B +2283B +2072C -2137C +2197C +2227C -2237C -2282C +2136D -2167D +2239D +2282A +2154C -2250C
view details
Other Other 35% -2065B +2283B +2072C -2137C +2197C +2227C -2237C -2282C +2136D -2167D +2239D +2282A +2154C -2250C
view details
Other Other 35% -2065B +2283B +2072C -2137C +2197C +2227C -2237C -2282C +2136D -2167D +2239D +2282A +2154C -2250C
view details
Other Other 35% -2065B +2283B +2072C -2137C +2197C +2227C -2237C -2282C +2136D -2167D +2239D +2282A +2154C -2250C
view details
Other Other 35% -2065B +2283B +2072C -2137C +2197C +2227C -2237C -2282C +2136D -2167D +2239D +2282A +2154C -2250C
view details
Other Other 35% -2065B +2283B +2072C -2137C +2197C +2227C -2237C -2282C +2136D -2167D +2239D +2282A +2154C -2250C
view details
Other Other 35% -2065B +2283B +2072C -2137C +2197C +2227C -2237C -2282C +2136D -2167D +2239D +2282A +2154C -2250C
view details
Other Other 35% -2065B +2283B +2072C -2137C +2197C +2227C -2237C -2282C +2136D -2167D +2239D +2282A +2154C -2250C
view details
Other Other 35% -2065B +2283B +2072C -2137C +2197C +2227C -2237C -2282C +2136D -2167D +2239D +2282A +2154C -2250C
view details
Other Other 35% -2065B +2283B +2072C -2137C +2197C +2227C -2237C -2282C +2136D -2167D +2239D +2282A +2154C -2250C
view details
Other Other 35% -2065B +2283B +2072C -2137C +2197C +2227C -2237C -2282C +2136D -2167D +2239D +2282A +2154C -2250C
view details
Other Other 35% -2065B +2283B +2072C -2137C +2197C +2227C -2237C -2282C +2136D -2167D +2239D +2282A +2154C -2250C
view details
Other Other 35% -2065B +2283B +2072C -2137C +2197C +2227C -2237C -2282C +2136D -2167D +2239D +2282A +2154C -2250C
view details
Other Other 35% -2065B +2283B +2072C -2137C +2197C +2227C -2237C -2282C +2136D -2167D +2239D +2282A +2154C -2250C
view details
Other Other 35% -2065B +2283B +2072C -2137C +2197C +2227C -2237C -2282C +2136D -2167D +2239D +2282A +2154C -2250C
view details
Other Other 35% -2065B +2283B +2072C -2137C +2197C +2227C -2237C -2282C +2136D -2167D +2239D +2282A +2154C -2250C
view details
Other Other 35% -2065B +2283B +2072C -2137C +2197C +2227C -2237C -2282C +2136D -2167D +2239D +2282A +2154C -2250C
view details
Other Other 35% -2065B +2283B +2072C -2137C +2197C +2227C -2237C -2282C +2136D -2167D +2239D +2282A +2154C -2250C
view details
Other Other 35% -2065B +2283B +2072C -2137C +2197C +2227C -2237C -2282C +2136D -2167D +2239D +2282A +2154C -2250C
view details
Other Other 35% -2065B +2283B +2072C -2137C +2197C +2227C -2237C -2282C +2136D -2167D +2239D +2282A +2154C -2250C
Interpreting sequences
Chain A Sequence
GAMAGSYKKIRSNVYVDVKPLSGYEATTCNCKKPDDDTRKGCVDDCLNRMIFAECSPNTCPCGEQCCNQRIQRHEWVQCLERFRAEEKGWGIRTKEPLKAGQFIIEYLGEVVSEQEFRNRMIEQYHNHSDHYCLNLDSGMVIDSYRMGNEARFINHSCDPNCEMQKWSVNGVYRIGLYALKDMPAGTELTYDYNFHSFNVEKAQLCKCGFEKCRGIIGG
Chain A Sequence
GAMAGSYKKIRSNVYVDVKPLSGYEATTCNCKKPDDDTRKGCVDDCLNRMIFAECSPNTCPCGEQCCNQRIQRHEWVQCLERFRAEEKGWGIRTKEPLKAGQFIIEYLGEVVSEQEFRNRMIEQYHNHSDHYCLNLDSGMVIDSYRMGNEARFINHSCDPNCEMQKWSVNGVYRIGLYALKDMPAGTELTYDYNFHSFNVEKAQLCKCGFEKCRGIIGGK
Chain A Sequence
GAMAGSYKKIRSNVYVDVKPLSGYEATTCNCKKPDDDTRKGCVDDCLNRMIFAECSPNTCPCGEQCCNQRIQRHEWVQCLERFRAEEKGWGIRTKEPLKAGQFIIEYLGEVVSEQEFRNRMIEQYHNHSDHYCLNLDSGMVIDSYRMGNEARFINHSCDPNCEMQKWSVNGVYRIGLYALKDMPAGTELTYDYNFHSFNVEKAQLCKCGFEKCRGIIGGK
Chain A Sequence
GAMAGSYKKIRSNVYVDVKPLSGYEATTCNCKKPDDDTRKGCVDDCLNRMIFAECSPNTCPCGEQCCNQRIQRHEWVQCLERFRAEEKGWGIRTKEPLKAGQFIIEYLGEVVSEQEFRNRMIEQYHNHSDHYCLNLDSGMVIDSYRMGNEARFINHSCDPNCEMQKWSVNGVYRIGLYALKDMPAGTELTYDYNFHSFNVEKAQLCKCGFEKCRGIIGGK
sequence length 219,220,220,220
structure length 219,220,220,220
publication title Ash1L SET domain Q2265A mutant in complex with AS-5
rcsb
molecule tags Protein binding, transferase/inhibitor
molecule keywords Histone-lysine N-methyltransferase ASH1L
source organism Homo sapiens
ec nomenclature ec 2.1.1.359: [Histone H3]-lysine(36) N-trimethyltransferase.
ec 2.1.1.359: [Histone H3]-lysine(36) N-trimethyltransferase.
ec 2.1.1.359: [Histone H3]-lysine(36) N-trimethyltransferase.
ec 2.1.1.359: [Histone H3]-lysine(36) N-trimethyltransferase.
pdb deposition date2020-05-17
LinkProt deposition date2021-04-14
Image from the rcsb pdb (www.rcsb.org)
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LinkProt | Interdisciplinary Laboratory of Biological Systems Modelling