6UVABENP

Cryoem structure of the active adrenomedullin 2 receptor g protein complex with adrenomedullin 2 peptide
Other
37%
Link type Probability Chain B piercings Chain E piercings Chain N piercings Chain P piercings
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Other Other 37% +143E +266N -1P -341B -48N -340P -29P
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Other Other 37% +143E +266N -1P -341B -48N -340P -29P
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Other Other 37% +143E +266N -1P -341B -48N -340P -29P
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Other Other 37% +143E +266N -1P -341B -48N -340P -29P
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Other Other 37% +143E +266N -1P -341B -48N -340P -29P
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Other Other 37% +143E +266N -1P -341B -48N -340P -29P
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Other Other 37% +143E +266N -1P -341B -48N -340P -29P
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Other Other 37% +143E +266N -1P -341B -48N -340P -29P
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Other Other 37% +143E +266N -1P -341B -48N -340P -29P
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Other Other 37% +143E +266N -1P -341B -48N -340P -29P
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Other Other 37% +143E +266N -1P -341B -48N -340P -29P
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Other Other 37% +143E +266N -1P -341B -48N -340P -29P
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Other Other 37% +143E +266N -1P -341B -48N -340P -29P
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Other Other 37% +143E +266N -1P -341B -48N -340P -29P
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Other Other 37% +143E +266N -1P -341B -48N -340P -29P
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Other Other 37% +143E +266N -1P -341B -48N -340P -29P
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Other Other 37% +143E +266N -1P -341B -48N -340P -29P
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Other Other 37% +143E +266N -1P -341B -48N -340P -29P
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Other Other 37% +143E +266N -1P -341B -48N -340P -29P
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Other Other 37% +143E +266N -1P -341B -48N -340P -29P
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Other Other 37% +143E +266N -1P -341B -48N -340P -29P
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Other Other 37% +143E +266N -1P -341B -48N -340P -29P
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Other Other 37% +143E +266N -1P -341B -48N -340P -29P
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Other Other 37% +143E +266N -1P -341B -48N -340P -29P
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Other Other 37% +143E +266N -1P -341B -48N -340P -29P
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Other Other 37% +143E +266N -1P -341B -48N -340P -29P
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Other Other 37% +143E +266N -1P -341B -48N -340P -29P
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Other Other 37% +143E +266N -1P -341B -48N -340P -29P
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Other Other 37% +143E +266N -1P -341B -48N -340P -29P
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Other Other 37% +143E +266N -1P -341B -48N -340P -29P
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Other Other 37% +143E +266N -1P -341B -48N -340P -29P
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Other Other 37% +143E +266N -1P -341B -48N -340P -29P
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Other Other 37% +143E +266N -1P -341B -48N -340P -29P
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Other Other 37% +143E +266N -1P -341B -48N -340P -29P
Interpreting sequences
Chain B Sequence
DQLRQEAEQLKNQIRDARKACADATLSQITNNIDPVGRIQMRTRRTLRGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTDDGMAVATGSWDSFLKIWN
Chain B Sequence
MLERLPLCGKAFADMMGKVDVWKWCNLSEFIVYYESFTNCTEMEANVVGCYWPNPLAQGFITGIHRQFFSNCTVDRVHLEDPPDEVLIPLIVIPVVLTVAMAGLVVWRSKR
Chain B Sequence
QVQLQESGGGLVQPGGSLRLSCAASGFTFSNYKMNWVRQAPGKGLEWVSDISQSGASISYTGSVKGRFTISRDNAKNTLYLQMNSLKPEDTAVYYCARCPAPFTRDCFDVTSTTYAYRGQGTQVTV
Chain B Sequence
LLRVGCVLGTCQVQNLSHRLWQLMGPAGRQDSAPVDPSSPHSY
100200300−50510152025
Chain BPiercing position along the chainNumber of piercings
sequence length 336,111,126,43
structure length 336,111,126,43
publication title Structure and Dynamics of Adrenomedullin Receptors AM1and AM2Reveal Key Mechanisms in the Control of Receptor Phenotype by Receptor Activity-Modifying Proteins.
pubmed doi rcsb
molecule tags Membrane protein
molecule keywords Guanine nucleotide-binding protein G(s) subunit alpha isoforms short
source organism Homo sapiens
pdb deposition date2019-11-01
LinkProt deposition date2021-04-30

pfam database annotations

chain Pfam Accession CodePfam Family IdentifierPfam Description
BENP PF00400 WD40WD domain, G-beta repeat
BENP PF04901 RAMPReceptor activity modifying family
Image from the rcsb pdb (www.rcsb.org)


Warning
  • This is a unique chain - no homologues found.



 
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LinkProt | Interdisciplinary Laboratory of Biological Systems Modelling
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