5WHKABHL

Crystal structure of fab fragment of antibody dx-2507 bound to fcrn-b2m
A: 51-57,167-176 H: 130-137
Link type Probability Loop ranges Chain A piercings Chain B piercings Chain H piercings Chain L piercings
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Other Other 31% -A +3L -24L -159L -270A -212H -270L
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Other Other 31% -A +3L -24L -159L -270A -212H -270L
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Other Other 31% -A +3L -24L -159L -270A -212H -270L
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Other Other 31% -A +3L -24L -159L -270A -212H -270L
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Other Other 31% -A +3L -24L -159L -270A -212H -270L
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Other Other 31% -A +3L -24L -159L -270A -212H -270L
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Other Other 31% -A +3L -24L -159L -270A -212H -270L
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Other Other 31% -A +3L -24L -159L -270A -212H -270L
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Other Other 31% -A +3L -24L -159L -270A -212H -270L
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Other Other 31% -A +3L -24L -159L -270A -212H -270L
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Other Other 31% -A +3L -24L -159L -270A -212H -270L
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Other Other 31% -A +3L -24L -159L -270A -212H -270L
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Other Other 31% -A +3L -24L -159L -270A -212H -270L
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Other Other 31% -A +3L -24L -159L -270A -212H -270L
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Other Other 31% -A +3L -24L -159L -270A -212H -270L
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Other Other 31% -A +3L -24L -159L -270A -212H -270L
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Other Other 31% -A +3L -24L -159L -270A -212H -270L
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Other Other 31% -A +3L -24L -159L -270A -212H -270L
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Other Other 31% -A +3L -24L -159L -270A -212H -270L
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Other Other 31% -A +3L -24L -159L -270A -212H -270L
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Other Other 31% -A +3L -24L -159L -270A -212H -270L
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Other Other 31% -A +3L -24L -159L -270A -212H -270L
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Other Other 31% -A +3L -24L -159L -270A -212H -270L
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Other Other 31% -A +3L -24L -159L -270A -212H -270L
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Other Other 31% -A +3L -24L -159L -270A -212H -270L
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Other Other 31% -A +3L -24L -159L -270A -212H -270L
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Other Other 31% -A +3L -24L -159L -270A -212H -270L
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Other Other 31% -A +3L -24L -159L -270A -212H -270L
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Other Other 31% -A +3L -24L -159L -270A -212H -270L
view details
Other Other 31% -A +3L -24L -159L -270A -212H -270L
view details
Other Other 31% -A +3L -24L -159L -270A -212H -270L
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Other Other 31% -A +3L -24L -159L -270A -212H -270L
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Other Other 31% -A +3L -24L -159L -270A -212H -270L
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Other Other 31% -A +3L -24L -159L -270A -212H -270L
Interpreting sequences
Chain A Sequence
HLSLLYHLTAVSSPAPGTPAFWVSGWLGPQQYLSYNSLRGEAEPCGAW-----VSWYWEKETTDLRIKEKLFLEAFKALGGKGPYTLQGLLGCELGPDNTSVPTAKFALNGEEFMNFDLKQGTWGGDWPEALAISQRWQQQDKAANKELTFLLFSCPHRLREHL--------WKEPPSMRLKARPSSPGFSVLTCSAFSFYPPELQLRFLRNGLAAGTGQGDFGPNSDGSFHASSSLTVKSGDEHHYCCIVQHAGLAQPLRVELESP
Chain A Sequence
IQRTPKIQVYSRHPAENGKSNFLNCYVSGFHPSDIEVDLLKNGERIEKVEHSDLSFSKDWSFYLLYYTEFTPTEKDEYACRVNHVTLSQPKIVKWDRDM
Chain A Sequence
EVQLLESGGGLVQPGGSLRLSCAASGFTFSEYAMGWVRQAPGKGLEWVSSIGSSGGQTKYADSVKGRFTISRDNSKNTLYLQMNSLRAEDTAVYYCARLAIGDSYWGQGTMVTVSSASTKGPSVFPLAPS------GTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKRVEPK
Chain A Sequence
QSALTQPASVSGSPGQSITISCTGTGSDVGSYNLVSWYQQHPGKAPKLMIYGDSQRPSGVSNRFSGSKSGNTASLTISGLQAEDEADYYCASYAGSGIYVFGTGTKVTVLGQPKANPTVTLFPPSSEELQANKATLVCLISDFYPGAVTVAWKADGSPVKAGVETTKPSKQSNNKYAASSYLSLTPEQWKSHRSYSCQVTHEGSTVEKTVAP
sequence length 267,99,217,212
structure length 254,99,211,212
publication title Structural characterization of an IgG targeting the neonatal Fc receptor through pH-insensitive CDR interactions
rcsb
molecule tags Immune system
molecule keywords DX-2507 Fab heavy chain
source organism Homo sapiens
missing residues A: 51-57,167-176 H: 130-137
pdb deposition date2017-07-17
LinkProt deposition date2017-09-11
Image from the rcsb pdb (www.rcsb.org)
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LinkProt | Interdisciplinary Laboratory of Biological Systems Modelling