| Link type | Probability | Loop ranges | Chain B piercings | Chain D piercings | Chain F piercings | Chain G piercings | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| view details |
 |
Other | 49% | -B | +125G -150G +184G -224G | -122F +136F -209F -225G | -23B +36B +81B -112B | |||||||||
| view details |
|
Other | 49% | -B | +125G -150G +184G -224G | -122F +136F -209F -225G | -23B +36B +81B -112B | |||||||||
| view details |
|
Other | 49% | -B | +125G -150G +184G -224G | -122F +136F -209F -225G | -23B +36B +81B -112B | |||||||||
| view details |
|
Other | 49% | -B | +125G -150G +184G -224G | -122F +136F -209F -225G | -23B +36B +81B -112B | |||||||||
| view details |
|
Other | 49% | -B | +125G -150G +184G -224G | -122F +136F -209F -225G | -23B +36B +81B -112B | |||||||||
| view details |
|
Other | 49% | -B | +125G -150G +184G -224G | -122F +136F -209F -225G | -23B +36B +81B -112B | |||||||||
| view details |
|
Other | 49% | -B | +125G -150G +184G -224G | -122F +136F -209F -225G | -23B +36B +81B -112B | |||||||||
| view details |
|
Other | 49% | -B | +125G -150G +184G -224G | -122F +136F -209F -225G | -23B +36B +81B -112B | |||||||||
| view details |
|
Other | 49% | -B | +125G -150G +184G -224G | -122F +136F -209F -225G | -23B +36B +81B -112B | |||||||||
| view details |
|
Other | 49% | -B | +125G -150G +184G -224G | -122F +136F -209F -225G | -23B +36B +81B -112B | |||||||||
| view details |
|
Other | 49% | -B | +125G -150G +184G -224G | -122F +136F -209F -225G | -23B +36B +81B -112B | |||||||||
| view details |
|
Other | 49% | -B | +125G -150G +184G -224G | -122F +136F -209F -225G | -23B +36B +81B -112B | |||||||||
| view details |
|
Other | 49% | -B | +125G -150G +184G -224G | -122F +136F -209F -225G | -23B +36B +81B -112B | |||||||||
| view details |
|
Other | 49% | -B | +125G -150G +184G -224G | -122F +136F -209F -225G | -23B +36B +81B -112B | |||||||||
| view details |
|
Other | 49% | -B | +125G -150G +184G -224G | -122F +136F -209F -225G | -23B +36B +81B -112B | |||||||||
| view details |
|
Other | 49% | -B | +125G -150G +184G -224G | -122F +136F -209F -225G | -23B +36B +81B -112B | |||||||||
| view details |
|
Other | 49% | -B | +125G -150G +184G -224G | -122F +136F -209F -225G | -23B +36B +81B -112B | |||||||||
| view details |
|
Other | 49% | -B | +125G -150G +184G -224G | -122F +136F -209F -225G | -23B +36B +81B -112B | |||||||||
| view details |
|
Other | 49% | -B | +125G -150G +184G -224G | -122F +136F -209F -225G | -23B +36B +81B -112B | |||||||||
| view details |
|
Other | 49% | -B | +125G -150G +184G -224G | -122F +136F -209F -225G | -23B +36B +81B -112B | |||||||||
| view details |
|
Other | 49% | -B | +125G -150G +184G -224G | -122F +136F -209F -225G | -23B +36B +81B -112B | |||||||||
| view details |
|
Other | 49% | -B | +125G -150G +184G -224G | -122F +136F -209F -225G | -23B +36B +81B -112B | |||||||||
| view details |
|
Other | 49% | -B | +125G -150G +184G -224G | -122F +136F -209F -225G | -23B +36B +81B -112B | |||||||||
| view details |
|
Other | 49% | -B | +125G -150G +184G -224G | -122F +136F -209F -225G | -23B +36B +81B -112B | |||||||||
| view details |
|
Other | 49% | -B | +125G -150G +184G -224G | -122F +136F -209F -225G | -23B +36B +81B -112B | |||||||||
| view details |
|
Other | 49% | -B | +125G -150G +184G -224G | -122F +136F -209F -225G | -23B +36B +81B -112B | |||||||||
| view details |
|
Other | 49% | -B | +125G -150G +184G -224G | -122F +136F -209F -225G | -23B +36B +81B -112B | |||||||||
| view details |
|
Other | 49% | -B | +125G -150G +184G -224G | -122F +136F -209F -225G | -23B +36B +81B -112B | |||||||||
| view details |
|
Other | 49% | -B | +125G -150G +184G -224G | -122F +136F -209F -225G | -23B +36B +81B -112B | |||||||||
| view details |
|
Other | 49% | -B | +125G -150G +184G -224G | -122F +136F -209F -225G | -23B +36B +81B -112B | |||||||||
| view details |
|
Other | 49% | -B | +125G -150G +184G -224G | -122F +136F -209F -225G | -23B +36B +81B -112B | |||||||||
| view details |
|
Other | 49% | -B | +125G -150G +184G -224G | -122F +136F -209F -225G | -23B +36B +81B -112B | |||||||||
Chain B Sequence |
ELQLQESGPGLVKPSQTLSLTCTVSGGSISSGGYYWSWIRQHPGKGLEWIGYIYYSGSTYYNPSLKSRVTISVDTSKNQFSLKLSSVTAADTAVYYCARTPTVTGDWFDPWGRGTLVTVSSASTKGPSVFPLAPSSK----GTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSC |
Chain B Sequence |
SSTKKTQLQLEHLLLDLQMILNGINNYKNPKLTRMLTFKFYMPKKATELKHLQCLEEELKPLEEVLNLAQSKNFHLRPRDLISNINVIVLELKG---TFMCEYADETATIVEFLNRWITFCQSIISTLT |
Chain B Sequence |
ELQLQESGPGLVKPSQTLSLTCTVSGGSISSGGYYWSWIRQHPGKGLEWIGYIYYSGSTYYNPSLKSRVTISVDTSKNQFSLKLSSVTAADTAVYYCARTPTVTGDWFDPWGRGTLVTVSSASTKGPSVFPLAPSSK-TSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSC |
Chain B Sequence |
NFMLTQPHSVSESPGKTVTISCTRSSGSIASNYVQWYQQRPGSSPTTVIYEDNQRPSGVPDRFSGSIDSSSNSASLTISGLKTEDEADYYCQSYDSSNVVFGGGTKLTVLGQPKAAPSVTLFPPSSEELQANKATLVCLISDFYPGAVTVAWKADSSPVKAGVETTTPSKQSNNKYAASSYLSLTPEQWKSHRSYSCQVTHEGSTVEKTVAPT |
| sequence length | 224,129,224,213 |
| structure length | 220,126,223,213 |
| publication title |
A human anti-IL-2 antibody that potentiates regulatory T cells by a structure-based mechanism.
pubmed doi rcsb |
| molecule tags | Cytokine/immune system |
| molecule keywords | Fab 5111 heavy chain |
| source organism | Homo sapiens |
| missing residues | B: 137-142 D: 98-102 F: 137-139 |
| pdb deposition date | 2017-02-15 |
| LinkProt deposition date | 2018-07-14 |
Image from the rcsb pdb (www.rcsb.org)#similar chains in the LinkProt database (?% sequence similarity) ...loading similar chains, please wait... #similar chains, but unlinked ...loading similar chains, please wait... #similar chains in the pdb database (?% sequence similarity) ...loading similar chains, please wait...
