5T35BDFG

The protac mz1 in complex with the second bromodomain of brd4 and pvhl:elonginc:elonginb
G: 48-58
Link type Probability Chain B piercings Chain D piercings Chain F piercings Chain G piercings
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Other Other 30% -154D -104F +113G
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Other Other 30% -154D -104F +113G
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Other Other 30% -154D -104F +113G
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Other Other 30% -154D -104F +113G
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Other Other 30% -154D -104F +113G
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Other Other 30% -154D -104F +113G
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Other Other 30% -154D -104F +113G
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Other Other 30% -154D -104F +113G
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Other Other 30% -154D -104F +113G
view details
Other Other 30% -154D -104F +113G
view details
Other Other 30% -154D -104F +113G
view details
Other Other 30% -154D -104F +113G
view details
Other Other 30% -154D -104F +113G
view details
Other Other 30% -154D -104F +113G
view details
Other Other 30% -154D -104F +113G
view details
Other Other 30% -154D -104F +113G
view details
Other Other 30% -154D -104F +113G
view details
Other Other 30% -154D -104F +113G
view details
Other Other 30% -154D -104F +113G
view details
Other Other 30% -154D -104F +113G
view details
Other Other 30% -154D -104F +113G
view details
Other Other 30% -154D -104F +113G
Interpreting sequences
Chain B Sequence
MDVFLMIRRHKTTIFTDAKESSTVFELKRIVEGILKRPPDEQRLYKDDQLLDDGKTLGECGFTSQTARPQAPATVGLAFRADDTFEALCIEPFSSPPELPDVMK
Chain B Sequence
PVLRSVNSREPSQVIFCNRSPRVVLPVWLNFDGEPQPYPTLPPGTGRRIHSYRGHLWLFRDAGTHDGLLVNQTELFVPSLNVDGQPIFANITLPVYTLKERCLQVVRSLVKPENYRRLDIVRSLYEDLEDHPNVQKDLERLTQERIAHQ
Chain B Sequence
MDVFLMIRRHKTTIFTDAKESSTVFELKRIVEGILKRPPDEQRLYKDDQLLDDGKTLGECGFTSQTARPQAPATVGLAFRADDTFEALCIEPFSSPPELPDVMK
Chain B Sequence
MMYVKLISSDGHEFIVKREHALTSGTIKAMLSG---------NEVNFREIPSHVLSKVCMYFTYKVRYTNSSTEIPEFPIAPEIALELLMAANFLDC
sequence length 104,149,104,97
structure length 104,149,104,88
publication title Structural basis of PROTAC cooperative recognition for selective protein degradation
doi rcsb
molecule tags Ligase
molecule keywords Bromodomain-containing protein 4
source organism Homo sapiens
missing residues G: 48-58
pdb deposition date2016-08-24
LinkProt deposition date2017-03-14
Image from the rcsb pdb (www.rcsb.org)
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LinkProt | Interdisciplinary Laboratory of Biological Systems Modelling