5T35BCDE

The protac mz1 in complex with the second bromodomain of brd4 and pvhl:elonginc:elonginb
C: 47-58
Link type Probability Chain B piercings Chain C piercings Chain D piercings Chain E piercings
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Interpreting sequences
Chain B Sequence
MDVFLMIRRHKTTIFTDAKESSTVFELKRIVEGILKRPPDEQRLYKDDQLLDDGKTLGECGFTSQTARPQAPATVGLAFRADDTFEALCIEPFSSPPELPDVMK
Chain B Sequence
MMYVKLISSDGHEFIVKREHALTSGTIKAMLS----------NEVNFREIPSHVLSKVCMYFTYKVRYTNSSTEIPEFPIAPEIALELLMAANFLDC
Chain B Sequence
PVLRSVNSREPSQVIFCNRSPRVVLPVWLNFDGEPQPYPTLPPGTGRRIHSYRGHLWLFRDAGTHDGLLVNQTELFVPSLNVDGQPIFANITLPVYTLKERCLQVVRSLVKPENYRRLDIVRSLYEDLEDHPNVQKDLERLTQERIAHQ
Chain B Sequence
KVSEQLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPD
sequence length 104,97,149,111
structure length 104,87,149,111
publication title Structural basis of PROTAC cooperative recognition for selective protein degradation
doi rcsb
molecule tags Ligase
molecule keywords Bromodomain-containing protein 4
source organism Homo sapiens
missing residues C: 47-58
pdb deposition date2016-08-24
LinkProt deposition date2017-03-14
Image from the rcsb pdb (www.rcsb.org)
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LinkProt | Interdisciplinary Laboratory of Biological Systems Modelling