5QJ2FHI

Crystal structure of myeloperoxidase subform c (mpo) omplex with compound-20 aka 7-((3-(1-methyl-1h-pyrazol-3- yl)benzyl)oxy)- 1h-[1,2,3]triazolo[4,5-b]pyridin-5-amine
Link type Probability Loop ranges Chain F piercings Chain H piercings Chain I piercings
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Hopf.2 U Ring Hopf.2 U Ring 32% -F -578F -51I -288F +338F -429F +530F -14H +104H
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Hopf.2 U Ring Hopf.2 U Ring 32% -F -578F -51I -288F +338F -429F +530F -14H +104H
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Hopf.2 U Ring Hopf.2 U Ring 32% -F -578F -51I -288F +338F -429F +530F -14H +104H
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Hopf.2 U Ring Hopf.2 U Ring 32% -F -578F -51I -288F +338F -429F +530F -14H +104H
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Hopf.2 U Ring Hopf.2 U Ring 32% -F -578F -51I -288F +338F -429F +530F -14H +104H
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Hopf.2 U Ring Hopf.2 U Ring 32% -F -578F -51I -288F +338F -429F +530F -14H +104H
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Hopf.2 U Ring Hopf.2 U Ring 32% -F -578F -51I -288F +338F -429F +530F -14H +104H
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Hopf.2 U Ring Hopf.2 U Ring 32% -F -578F -51I -288F +338F -429F +530F -14H +104H
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Hopf.2 U Ring Hopf.2 U Ring 32% -F -578F -51I -288F +338F -429F +530F -14H +104H
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Hopf.2 U Ring Hopf.2 U Ring 32% -F -578F -51I -288F +338F -429F +530F -14H +104H
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Hopf.2 U Ring Hopf.2 U Ring 32% -F -578F -51I -288F +338F -429F +530F -14H +104H
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Hopf.2 U Ring Hopf.2 U Ring 32% -F -578F -51I -288F +338F -429F +530F -14H +104H
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Hopf.2 U Ring Hopf.2 U Ring 32% -F -578F -51I -288F +338F -429F +530F -14H +104H
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Hopf.2 U Ring Hopf.2 U Ring 32% -F -578F -51I -288F +338F -429F +530F -14H +104H
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Hopf.2 U Ring Hopf.2 U Ring 32% -F -578F -51I -288F +338F -429F +530F -14H +104H
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Hopf.2 U Ring Hopf.2 U Ring 32% -F -578F -51I -288F +338F -429F +530F -14H +104H
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Hopf.2 U Ring Hopf.2 U Ring 32% -F -578F -51I -288F +338F -429F +530F -14H +104H
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Hopf.2 U Ring Hopf.2 U Ring 32% -F -578F -51I -288F +338F -429F +530F -14H +104H
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Hopf.2 U Ring Hopf.2 U Ring 32% -F -578F -51I -288F +338F -429F +530F -14H +104H
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Hopf.2 U Ring Hopf.2 U Ring 32% -F -578F -51I -288F +338F -429F +530F -14H +104H
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Hopf.2 U Ring Hopf.2 U Ring 32% -F -578F -51I -288F +338F -429F +530F -14H +104H
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Hopf.2 U Ring Hopf.2 U Ring 32% -F -578F -51I -288F +338F -429F +530F -14H +104H
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Hopf.2 U Ring Hopf.2 U Ring 32% -F -578F -51I -288F +338F -429F +530F -14H +104H
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Hopf.2 U Ring Hopf.2 U Ring 32% -F -578F -51I -288F +338F -429F +530F -14H +104H
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Hopf.2 U Ring Hopf.2 U Ring 32% -F -578F -51I -288F +338F -429F +530F -14H +104H
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Hopf.2 U Ring Hopf.2 U Ring 32% -F -578F -51I -288F +338F -429F +530F -14H +104H
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Hopf.2 U Ring Hopf.2 U Ring 32% -F -578F -51I -288F +338F -429F +530F -14H +104H
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Hopf.2 U Ring Hopf.2 U Ring 32% -F -578F -51I -288F +338F -429F +530F -14H +104H
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Hopf.2 U Ring Hopf.2 U Ring 32% -F -578F -51I -288F +338F -429F +530F -14H +104H
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Hopf.2 U Ring Hopf.2 U Ring 32% -F -578F -51I -288F +338F -429F +530F -14H +104H
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Hopf.2 U Ring Hopf.2 U Ring 32% -F -578F -51I -288F +338F -429F +530F -14H +104H
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Hopf.2 U Ring Hopf.2 U Ring 32% -F -578F -51I -288F +338F -429F +530F -14H +104H
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Hopf.2 U Ring Hopf.2 U Ring 32% -F -578F -51I -288F +338F -429F +530F -14H +104H
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Hopf.2 U Ring Hopf.2 U Ring 32% -F -578F -51I -288F +338F -429F +530F -14H +104H
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Hopf.2 U Ring Hopf.2 U Ring 32% -F -578F -51I -288F +338F -429F +530F -14H +104H
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Hopf.2 U Ring Hopf.2 U Ring 32% -F -578F -51I -288F +338F -429F +530F -14H +104H
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Hopf.2 U Ring Hopf.2 U Ring 32% -F -578F -51I -288F +338F -429F +530F -14H +104H
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Hopf.2 U Ring Hopf.2 U Ring 32% -F -578F -51I -288F +338F -429F +530F -14H +104H
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Hopf.2 U Ring Hopf.2 U Ring 32% -F -578F -51I -288F +338F -429F +530F -14H +104H
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Hopf.2 U Ring Hopf.2 U Ring 32% -F -578F -51I -288F +338F -429F +530F -14H +104H
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Hopf.2 U Ring Hopf.2 U Ring 32% -F -578F -51I -288F +338F -429F +530F -14H +104H
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Hopf.2 U Ring Hopf.2 U Ring 32% -F -578F -51I -288F +338F -429F +530F -14H +104H
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Hopf.2 U Ring Hopf.2 U Ring 32% -F -578F -51I -288F +338F -429F +530F -14H +104H
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Hopf.2 U Ring Hopf.2 U Ring 32% -F -578F -51I -288F +338F -429F +530F -14H +104H
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Hopf.2 U Ring Hopf.2 U Ring 32% -F -578F -51I -288F +338F -429F +530F -14H +104H
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Hopf.2 U Ring Hopf.2 U Ring 32% -F -578F -51I -288F +338F -429F +530F -14H +104H
Interpreting sequences
Chain F Sequence
CPEQDKYRTITGMCNNRRSPTLGASNRAFVRWLPAEYEDGFSLPYGWTPGVKRNGFPVALARAVSNEIVRFPTDQLTPDQERSLMFMQWGQLLDHDLDFTPEP
Chain F Sequence
CPEQDKYRTITGMCNNRRSPTLGASNRAFVRWLPAEYEDGFSLPYGWTPGVKRNGFPVALARAVSNEIVRFPTDQLTPDQERSLMFMQWGQLLDHDLDFTPEP
Chain F Sequence
VNCETSCVQQPPCFPLKIPPNDPRIKNQADCIPFFRSCPACPGSNITIRNQINALTSFVDASMVYGSEEPLARNLRNMSNQLGLLAVNQRFQDNGRALLPFDNLHDDPCLLTNRSARIPCFLAGDTRSSEMPELTSMHTLLLREHNRLATELKSLNPRWDGERLYQEARKIVGAMVQIITYRDYLPLVLGPTAMRKYLPTYRSYNDSVDPRIANVFTNAFRYGHTLIQPFMFRLDNRYQPMEPNPRVPLSRVFFASWRVVLEGGIDPILRGLMATPAKLNRQNQIAVDEIRERLFEQVMRIGLDLPALNMQRSRDHGLPGYNAWRRFCGLPQPETVGQLGTVLRNLKLARKLMEQYGTPNNIDIWMGGVSEPLKRKGRVGPLLACIIGTQFRKLRDGDRFWWENEGVFSMQQRQALAQISLPRIICDNTGITTVSKNNIFMSNSYPRDFVNCSTLPALNLASWRE
sequence length 103,103,465
structure length 103,103,465
publication title Potent Triazolopyridine Myeloperoxidase Inhibitors.
pubmed doi rcsb
molecule tags Metal binding protein
molecule keywords Myeloperoxidase
source organism Homo sapiens
pdb deposition date2018-09-26
LinkProt deposition date2019-02-08
Image from the rcsb pdb (www.rcsb.org)
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LinkProt | Interdisciplinary Laboratory of Biological Systems Modelling