5NG5JKM

Multi-drug efflux; membrane transport; rnd superfamily; drug resistance
Link type Probability Chain J piercings Chain K piercings Chain M piercings
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Other Other 34% -884K -1034M +46J -10M +351M -367M +409M +488M -539M +943M -977M +1022M -46J -542K
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Other Other 34% -884K -1034M +46J -10M +351M -367M +409M +488M -539M +943M -977M +1022M -46J -542K
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Other Other 34% -884K -1034M +46J -10M +351M -367M +409M +488M -539M +943M -977M +1022M -46J -542K
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Other Other 34% -884K -1034M +46J -10M +351M -367M +409M +488M -539M +943M -977M +1022M -46J -542K
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Other Other 34% -884K -1034M +46J -10M +351M -367M +409M +488M -539M +943M -977M +1022M -46J -542K
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Other Other 34% -884K -1034M +46J -10M +351M -367M +409M +488M -539M +943M -977M +1022M -46J -542K
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Other Other 34% -884K -1034M +46J -10M +351M -367M +409M +488M -539M +943M -977M +1022M -46J -542K
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Other Other 34% -884K -1034M +46J -10M +351M -367M +409M +488M -539M +943M -977M +1022M -46J -542K
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Other Other 34% -884K -1034M +46J -10M +351M -367M +409M +488M -539M +943M -977M +1022M -46J -542K
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Other Other 34% -884K -1034M +46J -10M +351M -367M +409M +488M -539M +943M -977M +1022M -46J -542K
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Other Other 34% -884K -1034M +46J -10M +351M -367M +409M +488M -539M +943M -977M +1022M -46J -542K
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Other Other 34% -884K -1034M +46J -10M +351M -367M +409M +488M -539M +943M -977M +1022M -46J -542K
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Other Other 34% -884K -1034M +46J -10M +351M -367M +409M +488M -539M +943M -977M +1022M -46J -542K
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Other Other 34% -884K -1034M +46J -10M +351M -367M +409M +488M -539M +943M -977M +1022M -46J -542K
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Other Other 34% -884K -1034M +46J -10M +351M -367M +409M +488M -539M +943M -977M +1022M -46J -542K
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Other Other 34% -884K -1034M +46J -10M +351M -367M +409M +488M -539M +943M -977M +1022M -46J -542K
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Other Other 34% -884K -1034M +46J -10M +351M -367M +409M +488M -539M +943M -977M +1022M -46J -542K
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Other Other 34% -884K -1034M +46J -10M +351M -367M +409M +488M -539M +943M -977M +1022M -46J -542K
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Other Other 34% -884K -1034M +46J -10M +351M -367M +409M +488M -539M +943M -977M +1022M -46J -542K
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Other Other 34% -884K -1034M +46J -10M +351M -367M +409M +488M -539M +943M -977M +1022M -46J -542K
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Other Other 34% -884K -1034M +46J -10M +351M -367M +409M +488M -539M +943M -977M +1022M -46J -542K
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Other Other 34% -884K -1034M +46J -10M +351M -367M +409M +488M -539M +943M -977M +1022M -46J -542K
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Other Other 34% -884K -1034M +46J -10M +351M -367M +409M +488M -539M +943M -977M +1022M -46J -542K
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Other Other 34% -884K -1034M +46J -10M +351M -367M +409M +488M -539M +943M -977M +1022M -46J -542K
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Other Other 34% -884K -1034M +46J -10M +351M -367M +409M +488M -539M +943M -977M +1022M -46J -542K
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Other Other 34% -884K -1034M +46J -10M +351M -367M +409M +488M -539M +943M -977M +1022M -46J -542K
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Other Other 34% -884K -1034M +46J -10M +351M -367M +409M +488M -539M +943M -977M +1022M -46J -542K
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Other Other 34% -884K -1034M +46J -10M +351M -367M +409M +488M -539M +943M -977M +1022M -46J -542K
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Other Other 34% -884K -1034M +46J -10M +351M -367M +409M +488M -539M +943M -977M +1022M -46J -542K
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Other Other 34% -884K -1034M +46J -10M +351M -367M +409M +488M -539M +943M -977M +1022M -46J -542K
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Other Other 34% -884K -1034M +46J -10M +351M -367M +409M +488M -539M +943M -977M +1022M -46J -542K
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Other Other 34% -884K -1034M +46J -10M +351M -367M +409M +488M -539M +943M -977M +1022M -46J -542K
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Other Other 34% -884K -1034M +46J -10M +351M -367M +409M +488M -539M +943M -977M +1022M -46J -542K
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Other Other 34% -884K -1034M +46J -10M +351M -367M +409M +488M -539M +943M -977M +1022M -46J -542K
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Other Other 34% -884K -1034M +46J -10M +351M -367M +409M +488M -539M +943M -977M +1022M -46J -542K
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Other Other 34% -884K -1034M +46J -10M +351M -367M +409M +488M -539M +943M -977M +1022M -46J -542K
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Other Other 34% -884K -1034M +46J -10M +351M -367M +409M +488M -539M +943M -977M +1022M -46J -542K
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Other Other 34% -884K -1034M +46J -10M +351M -367M +409M +488M -539M +943M -977M +1022M -46J -542K
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Other Other 34% -884K -1034M +46J -10M +351M -367M +409M +488M -539M +943M -977M +1022M -46J -542K
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Other Other 34% -884K -1034M +46J -10M +351M -367M +409M +488M -539M +943M -977M +1022M -46J -542K
view details
Other Other 34% -884K -1034M +46J -10M +351M -367M +409M +488M -539M +943M -977M +1022M -46J -542K
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Other Other 34% -884K -1034M +46J -10M +351M -367M +409M +488M -539M +943M -977M +1022M -46J -542K
Interpreting sequences
Chain J Sequence
MPNFFIDRPIFAWVIAIIIMLAGGLAILKLPVAQYPTIAPPAVTISASYPGADAKTVQDTVTQVIEQNMNGIDNLMYMSSNSDSTGTVQITLTFESGTDADIAQVQVQNKLQLAMPLLPQEVQQQGVSVEKSSSSFLMVVGVINTDGTMTQEDISDYVAANMKDAISRTSGVGDVQLFGSQYAMRIWMNPNELNKFQLTPVDVITAIKAQNAQVAAGQLGGTPPVKGQQLNASIIAQTRLTSTEEFGKILLKVNQDGSRVLLRDVAKIELGGENYDIIAEFNGQPASGLGIKLATGANALDTAAAIRAELAKMEPFFPSGLKIVYPYDTTPFVKISIHEVVKTLVEAIILVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFGMVLAIGLLVDDAIVVVENVERVMAEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMALSVLVALILTPALCATMLKPIAKGDHGEGKKGFFGWFNRMFEKSTHHYTDSVGGILRSTGRYLVLYLIIVVGMAYLFVRLPSSFLPDEDQGVFMTMVQLPAGATQERTQKVLNEVTHYYLTKEKNNVESVFAVNGFGFAGRGQNTGIAFVSLKDWADRPGEENKVEAITMRATRAFSQIKDAMVFAFNLPAIVELGTATGFDFELIDQAGLGHEKLTQARNQLLAEAAKHPDMLTSVRPNGLEDTPQFKIDIDQEKAQALGVSINDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYRMLPDDIGDWYVRAADGQMVPFSAFSSSRWEYGSPRLERYNGLPSMEILGQAAPGKSTGEAMELMEQLASKLPTGVGYDWTGMSYQERLSGNQAPSLYAISLIVVFLCLAALYESWSIPFSVMLVVPLGVIGALLAATFRGLTNDVYFQVGLLTTIGLSAKNAILIVEFAKDLMDKEGKGLIEATLDAVRMRLRPILMTSLAFILGVMPLVISTGAGSGAQNAVGTGVMGGMVTATVLAIFFVPVFFVVVRRRF
Chain J Sequence
MPNFFIDRPIFAWVIAIIIMLAGGLAILKLPVAQYPTIAPPAVTISASYPGADAKTVQDTVTQVIEQNMNGIDNLMYMSSNSDSTGTVQITLTFESGTDADIAQVQVQNKLQLAMPLLPQEVQQQGVSVEKSSSSFLMVVGVINTDGTMTQEDISDYVAANMKDAISRTSGVGDVQLFGSQYAMRIWMNPNELNKFQLTPVDVITAIKAQNAQVAAGQLGGTPPVKGQQLNASIIAQTRLTSTEEFGKILLKVNQDGSRVLLRDVAKIELGGENYDIIAEFNGQPASGLGIKLATGANALDTAAAIRAELAKMEPFFPSGLKIVYPYDTTPFVKISIHEVVKTLVEAIILVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINTLTMFGMVLAIGLLVDDAIVVVENVERVMAEEGLPPKEATRKSMGQIQGALVGIAMVLSAVFVPMAFFGGSTGAIYRQFSITIVSAMALSVLVALILTPALCATMLKPIAKGDHGEGKKGFFGWFNRMFEKSTHHYTDSVGGILRSTGRYLVLYLIIVVGMAYLFVRLPSSFLPDEDQGVFMTMVQLPAGATQERTQKVLNEVTHYYLTKEKNNVESVFAVNGFGFAGRGQNTGIAFVSLKDWADRPGEENKVEAITMRATRAFSQIKDAMVFAFNLPAIVELGTATGFDFELIDQAGLGHEKLTQARNQLLAEAAKHPDMLTSVRPNGLEDTPQFKIDIDQEKAQALGVSINDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYRMLPDDIGDWYVRAADGQMVPFSAFSSSRWEYGSPRLERYNGLPSMEILGQAAPGKSTGEAMELMEQLASKLPTGVGYDWTGMSYQERLSGNQAPSLYAISLIVVFLCLAALYESWSIPFSVMLVVPLGVIGALLAATFRGLTNDVYFQVGLLTTIGLSAKNAILIVEFAKDLMDKEGKGLIEATLDAVRMRLRPILMTSLAFILGVMPLVISTGAGSGAQNAVGTGVMGGMVTATVLAIFFVPVFFVVVRRRFSRKN
Chain J Sequence
MLELLKSLVFAVIMVPVVMAIILGLIYGLGEVFNIFSGVGKKDQPG
sequence length 1033,1037,46
structure length 1033,1037,46
publication title An allosteric transport mechanism for the AcrAB-TolC Multidrug Efflux Pump.
pubmed doi rcsb
molecule tags Membrane protein
molecule keywords Multidrug efflux pump subunit AcrA
source organism Escherichia coli
pdb deposition date2017-03-16
LinkProt deposition date2017-04-23
Image from the rcsb pdb (www.rcsb.org)
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LinkProt | Interdisciplinary Laboratory of Biological Systems Modelling