5N4BABD

Prolyl oligopeptidase b from galerina marginata bound to 25mer macrocyclization substrate - s577a mutant
Link type Probability Loop ranges Chain A piercings Chain B piercings Chain D piercings
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Other Other 37% -A -12A -661D +26A +26A +165B +570B +599B +659B -728B
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Other Other 37% -A -12A -661D +26A +26A +165B +570B +599B +659B -728B
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Other Other 37% -A -12A -661D +26A +26A +165B +570B +599B +659B -728B
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Other Other 37% -A -12A -661D +26A +26A +165B +570B +599B +659B -728B
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Other Other 37% -A -12A -661D +26A +26A +165B +570B +599B +659B -728B
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Other Other 37% -A -12A -661D +26A +26A +165B +570B +599B +659B -728B
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Other Other 37% -A -12A -661D +26A +26A +165B +570B +599B +659B -728B
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Other Other 37% -A -12A -661D +26A +26A +165B +570B +599B +659B -728B
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Other Other 37% -A -12A -661D +26A +26A +165B +570B +599B +659B -728B
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Other Other 37% -A -12A -661D +26A +26A +165B +570B +599B +659B -728B
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Other Other 37% -A -12A -661D +26A +26A +165B +570B +599B +659B -728B
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Other Other 37% -A -12A -661D +26A +26A +165B +570B +599B +659B -728B
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Other Other 37% -A -12A -661D +26A +26A +165B +570B +599B +659B -728B
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Other Other 37% -A -12A -661D +26A +26A +165B +570B +599B +659B -728B
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Other Other 37% -A -12A -661D +26A +26A +165B +570B +599B +659B -728B
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Other Other 37% -A -12A -661D +26A +26A +165B +570B +599B +659B -728B
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Other Other 37% -A -12A -661D +26A +26A +165B +570B +599B +659B -728B
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Other Other 37% -A -12A -661D +26A +26A +165B +570B +599B +659B -728B
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Other Other 37% -A -12A -661D +26A +26A +165B +570B +599B +659B -728B
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Other Other 37% -A -12A -661D +26A +26A +165B +570B +599B +659B -728B
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Other Other 37% -A -12A -661D +26A +26A +165B +570B +599B +659B -728B
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Other Other 37% -A -12A -661D +26A +26A +165B +570B +599B +659B -728B
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Other Other 37% -A -12A -661D +26A +26A +165B +570B +599B +659B -728B
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Other Other 37% -A -12A -661D +26A +26A +165B +570B +599B +659B -728B
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Other Other 37% -A -12A -661D +26A +26A +165B +570B +599B +659B -728B
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Other Other 37% -A -12A -661D +26A +26A +165B +570B +599B +659B -728B
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Other Other 37% -A -12A -661D +26A +26A +165B +570B +599B +659B -728B
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Other Other 37% -A -12A -661D +26A +26A +165B +570B +599B +659B -728B
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Other Other 37% -A -12A -661D +26A +26A +165B +570B +599B +659B -728B
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Other Other 37% -A -12A -661D +26A +26A +165B +570B +599B +659B -728B
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Other Other 37% -A -12A -661D +26A +26A +165B +570B +599B +659B -728B
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Other Other 37% -A -12A -661D +26A +26A +165B +570B +599B +659B -728B
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Other Other 37% -A -12A -661D +26A +26A +165B +570B +599B +659B -728B
Interpreting sequences
Chain A Sequence
WAPGNYPSTRRSDHVDTYQSASKGEVPVPDPYQWLEESTDEVDKWTTAQADLAQSYLDQNADIQKLAEKFRASRNYAKFSAPTLLDDGHWYWFYNRGLQSQSVLYRSKEPALPDFSKGDDNVGDVFFDPNVLAADGSAGMVLCKFSPDGKFFAYAVSHLGGDYSTIYVRSTSSPLSQASVAQGVDGRLSDEVKWFKFSTIIWTKDSKGFLYQRYPARERHEGTRSDRNAMMCYHKVGTTQEEDIIVYQDNEHPEWIYGADTSEDGKYLYLYQFKDTSKKNLLWVAELDEDGVKSGIHWRKVVNEYAADYNIITNHGSLVYIKTNLNAPQYKVITIDLSKDEPEIRDFIPEEKDAKLAQVNCANEEYFVAIYKRNVKDEIYLYSKAGVQLTRLAPDFVGAASIANRQKQTHFFLTLSGFNTPGTIARYDFTAPETQRFSILRTTKVNELDPDDFESTQVWYESKDGTKIPMFIVRHKSTKFDGTAAAIQYGYGGFATSADPFFSPIILTFLQTYGAIFAVPSIRGGGEFGEEWHKGGRRETKVNTFDDFIAAAQFLVKNKYAAPGKVAINGAANGGLLVMGSIVRAPEGTFGAAVPEGGVADLLKFHKFTGGQAWISEYGNPSIPEEFDYIYPLSPVHNVRTDKVMPATLITVNIGDGRVVPMHSFKFIATLQHNVPQNPHPLLIKIDKSWLGHGMGKPTDKNVKDAADKWGFIARALGLELK
Chain A Sequence
WAPGNYPSTRRSDHVDTYQSASKGEVPVPDPYQWLEESTDEVDKWTTAQADLAQSYLDQNADIQKLAEKFRASRNYAKFSAPTLLDDGHWYWFYNRGLQSQSVLYRSKEPALPDFSKGDDNVGDVFFDPNVLAADGSAGMVLCKFSPDGKFFAYAVSHLGGDYSTIYVRSTSSPLSQASVAQGVDGRLSDEVKWFKFSTIIWTKDSKGFLYQRYPARERHEGTRSDRNAMMCYHKVGTTQEEDIIVYQDNEHPEWIYGADTSEDGKYLYLYQFKDTSKKNLLWVAELDEDGVKSGIHWRKVVNEYAADYNIITNHGSLVYIKTNLNAPQYKVITIDLSKDEPEIRDFIPEEKDAKLAQVNCANEEYFVAIYKRNVKDEIYLYSKAGVQLTRLAPDFVGAASIANRQKQTHFFLTLSGFNTPGTIARYDFTAPETQRFSILRTTKVNELDPDDFESTQVWYESKDGTKIPMFIVRHKSTKFDGTAAAIQYGYGGFATSADPFFSPIILTFLQTYGAIFAVPSIRGGGEFGEEWHKGGRRETKVNTFDDFIAAAQFLVKNKYAAPGKVAINGAANGGLLVMGSIVRAPEGTFGAAVPEGGVADLLKFHKFTGGQAWISEYGNPSIPEEFDYIYPLSPVHNVRTDKVMPATLITVNIGDGRVVPMHSFKFIATLQHNVPQNPHPLLIKIDKSWLGHGMGKPTDKNVKDAADKWGFIARALGLELK
Chain A Sequence
WTAEHVDQTLASGNDIC
sequence length 722,722,17
structure length 722,722,17
publication title Characterization of a dual function macrocyclase enables design and use of efficient macrocyclization substrates
doi rcsb
molecule tags Hydrolase
molecule keywords Prolyl oligopeptidase
source organism Galerina marginata
pdb deposition date2017-02-10
LinkProt deposition date2017-11-04
Image from the rcsb pdb (www.rcsb.org)
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LinkProt | Interdisciplinary Laboratory of Biological Systems Modelling