| Link type | Probability | Chain A piercings | Chain B piercings | Chain C piercings | Chain D piercings | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
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Other | 48% | +179C -257C | +61A +94A -127A +164A -177A -269A | ||||||||||
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Other | 48% | +179C -257C | +61A +94A -127A +164A -177A -269A | ||||||||||
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Other | 48% | +179C -257C | +61A +94A -127A +164A -177A -269A | ||||||||||
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Other | 48% | +179C -257C | +61A +94A -127A +164A -177A -269A | ||||||||||
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Other | 48% | +179C -257C | +61A +94A -127A +164A -177A -269A | ||||||||||
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Other | 48% | +179C -257C | +61A +94A -127A +164A -177A -269A | ||||||||||
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Other | 48% | +179C -257C | +61A +94A -127A +164A -177A -269A | ||||||||||
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Other | 48% | +179C -257C | +61A +94A -127A +164A -177A -269A | ||||||||||
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Other | 48% | +179C -257C | +61A +94A -127A +164A -177A -269A | ||||||||||
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Other | 48% | +179C -257C | +61A +94A -127A +164A -177A -269A | ||||||||||
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Other | 48% | +179C -257C | +61A +94A -127A +164A -177A -269A | ||||||||||
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Other | 48% | +179C -257C | +61A +94A -127A +164A -177A -269A | ||||||||||
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Other | 48% | +179C -257C | +61A +94A -127A +164A -177A -269A | ||||||||||
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Other | 48% | +179C -257C | +61A +94A -127A +164A -177A -269A | ||||||||||
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Other | 48% | +179C -257C | +61A +94A -127A +164A -177A -269A | ||||||||||
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Other | 48% | +179C -257C | +61A +94A -127A +164A -177A -269A | ||||||||||
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Other | 48% | +179C -257C | +61A +94A -127A +164A -177A -269A | ||||||||||
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Other | 48% | +179C -257C | +61A +94A -127A +164A -177A -269A | ||||||||||
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Other | 48% | +179C -257C | +61A +94A -127A +164A -177A -269A | ||||||||||
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Other | 48% | +179C -257C | +61A +94A -127A +164A -177A -269A | ||||||||||
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Other | 48% | +179C -257C | +61A +94A -127A +164A -177A -269A | ||||||||||
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Other | 48% | +179C -257C | +61A +94A -127A +164A -177A -269A | ||||||||||
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Other | 48% | +179C -257C | +61A +94A -127A +164A -177A -269A | ||||||||||
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Other | 48% | +179C -257C | +61A +94A -127A +164A -177A -269A | ||||||||||
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Other | 48% | +179C -257C | +61A +94A -127A +164A -177A -269A | ||||||||||
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Other | 48% | +179C -257C | +61A +94A -127A +164A -177A -269A | ||||||||||
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Other | 48% | +179C -257C | +61A +94A -127A +164A -177A -269A | ||||||||||
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Other | 48% | +179C -257C | +61A +94A -127A +164A -177A -269A | ||||||||||
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Other | 48% | +179C -257C | +61A +94A -127A +164A -177A -269A | ||||||||||
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Other | 48% | +179C -257C | +61A +94A -127A +164A -177A -269A | ||||||||||
| view details |
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Other | 48% | +179C -257C | +61A +94A -127A +164A -177A -269A | ||||||||||
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Other | 48% | +179C -257C | +61A +94A -127A +164A -177A -269A | ||||||||||
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Other | 48% | +179C -257C | +61A +94A -127A +164A -177A -269A | ||||||||||
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Other | 48% | +179C -257C | +61A +94A -127A +164A -177A -269A | ||||||||||
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Other | 48% | +179C -257C | +61A +94A -127A +164A -177A -269A | ||||||||||
| view details |
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Other | 48% | +179C -257C | +61A +94A -127A +164A -177A -269A | ||||||||||
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Other | 48% | +179C -257C | +61A +94A -127A +164A -177A -269A | ||||||||||
Chain A Sequence |
EAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLV---------GKTVETQVAELIGTNAIAPFLLTMSFAQRQ---------SNLSIVNLCDAMVDQPMAFSLYNMGKHALVGLTQSAALELAPYGIRVNGVAPGVSLLPVAMGEEEKDKWRRKVPLGRREASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSLVHA |
Chain A Sequence |
EAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLV----------KTVETQVAELIGTNAIAPFLLTMSFAQRQ----------NLSIVNLCDAMVDQPMAFSLYNMGKHALVGLTQSAALELAPYGIRVNGVAPGVSLLPVAMGEEEKDKWRRKVPLGRREASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSLVHA |
Chain A Sequence |
MEAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVK----------TVETQVAELIGTNAIAPFLLTMSFAQRQS---------NLSIVNLCDAMVDQPMAFSLYNMGKHALVGLTQSAALELAPYGIRVNGVAPGVSLLPDK--------WRRKVPLGRREASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSLVHA |
Chain A Sequence |
EAPAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADLTNSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLV----------KTVETQVAELIGTNAIAPFLLTMSFAQRQ---------SNLSIVNLCDAMVDQPMAFSLYNMGKHALVGLTQSAALELAPYGIRVNGVAPGVSLLPVAMGEEEKDKWRRKVPLGRREASAEQIADAVIFLVSGSAQYITGSIIKVDGGLSLVHA |
| sequence length | 267,267,268,267 |
| structure length | 248,246,239,247 |
| publication title |
Structure-based design of 2-amino-1,3,4-thiadiazoles as PTR1 inhibitors for the treatment of Human African Trypanosomiasis
rcsb |
| molecule tags | Oxidoreductase |
| molecule keywords | Pteridine reductase |
| source organism | Trypanosoma brucei brucei |
| missing residues | A: 103-113,142-152 B: 103-114,142-153 C: 103-114,142-152,210-219 D: 103-114,142-152 |
| pdb deposition date | 2016-03-25 |
| LinkProt deposition date | 2017-04-08 |
Image from the rcsb pdb (www.rcsb.org)#similar chains in the LinkProt database (?% sequence similarity) ...loading similar chains, please wait... #similar chains, but unlinked ...loading similar chains, please wait... #similar chains in the pdb database (?% sequence similarity) ...loading similar chains, please wait...
