5GJQLRUY

Structure of the human 26s proteasome bound to usp14-ubal
U: 142-152 Y: 27-35
Link type Probability Chain L piercings Chain R piercings Chain U piercings Chain Y piercings
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Other Other 42% -358R -389U -8Y +100Y -121Y +137Y -158Y +207Y -248Y +295Y -69U -389Y -64Y
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Other Other 42% -358R -389U -8Y +100Y -121Y +137Y -158Y +207Y -248Y +295Y -69U -389Y -64Y
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Other Other 42% -358R -389U -8Y +100Y -121Y +137Y -158Y +207Y -248Y +295Y -69U -389Y -64Y
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Other Other 42% -358R -389U -8Y +100Y -121Y +137Y -158Y +207Y -248Y +295Y -69U -389Y -64Y
view details
Other Other 42% -358R -389U -8Y +100Y -121Y +137Y -158Y +207Y -248Y +295Y -69U -389Y -64Y
view details
Other Other 42% -358R -389U -8Y +100Y -121Y +137Y -158Y +207Y -248Y +295Y -69U -389Y -64Y
view details
Other Other 42% -358R -389U -8Y +100Y -121Y +137Y -158Y +207Y -248Y +295Y -69U -389Y -64Y
view details
Other Other 42% -358R -389U -8Y +100Y -121Y +137Y -158Y +207Y -248Y +295Y -69U -389Y -64Y
view details
Other Other 42% -358R -389U -8Y +100Y -121Y +137Y -158Y +207Y -248Y +295Y -69U -389Y -64Y
view details
Other Other 42% -358R -389U -8Y +100Y -121Y +137Y -158Y +207Y -248Y +295Y -69U -389Y -64Y
view details
Other Other 42% -358R -389U -8Y +100Y -121Y +137Y -158Y +207Y -248Y +295Y -69U -389Y -64Y
view details
Other Other 42% -358R -389U -8Y +100Y -121Y +137Y -158Y +207Y -248Y +295Y -69U -389Y -64Y
view details
Other Other 42% -358R -389U -8Y +100Y -121Y +137Y -158Y +207Y -248Y +295Y -69U -389Y -64Y
view details
Other Other 42% -358R -389U -8Y +100Y -121Y +137Y -158Y +207Y -248Y +295Y -69U -389Y -64Y
view details
Other Other 42% -358R -389U -8Y +100Y -121Y +137Y -158Y +207Y -248Y +295Y -69U -389Y -64Y
view details
Other Other 42% -358R -389U -8Y +100Y -121Y +137Y -158Y +207Y -248Y +295Y -69U -389Y -64Y
view details
Other Other 42% -358R -389U -8Y +100Y -121Y +137Y -158Y +207Y -248Y +295Y -69U -389Y -64Y
view details
Other Other 42% -358R -389U -8Y +100Y -121Y +137Y -158Y +207Y -248Y +295Y -69U -389Y -64Y
view details
Other Other 42% -358R -389U -8Y +100Y -121Y +137Y -158Y +207Y -248Y +295Y -69U -389Y -64Y
view details
Other Other 42% -358R -389U -8Y +100Y -121Y +137Y -158Y +207Y -248Y +295Y -69U -389Y -64Y
Interpreting sequences
Chain L Sequence
KLLEHKEIDGRLKELREQLKELTKQYEKSENDLKALQSVGQIVGEVLKQLTEEKFIVKATNGPRYVVGCRRQLDKSKLKPGTRVALDMTTLTIMRYLPREVDPLVYNMSHEDPGNVSYSEIGGLSEQIRELREVIELPLTNPELFQRVGIIPPKGCLLYGPPGTGKTLLARAVASQLDCNFLKVVSSSIVDKYIGESARLIREMFNYARDHQPCIIFMDEIDAIGGRRFSEGTSADREIQRTLMELLNQMDGFDTLHRVKMIMATNRPDTLDPALLRPGRLDRKIHIDLPNEQARLDILKIHAGPITKHGEIDYEAIVKLSDGFNGADLRNVCTEAGMFAIRADHDFVVQEDFMKAVRKVADSKKLESKLDYKPV
Chain L Sequence
NPDLRIAQLRFLLSLPEHRGDAAVRDELMAAVRDNNMAPYYEALCKSLDWQIDVDLLNKMKKANEDELKRLDEELEDAEKNLGESEIRDAMMAKAEYLCRIGDKEGALTAFRKTYDKTVALGHRLDIVFYLLRIGLFYMDNDLITRNTEKAKSLIEEGGDWDRRNRLKVYQGLYCVAIRDFKQAAELFLDTVSTFTSYELMDYKTFVTYTVYVSMIALERPDLREKVIKGAEILEVLHSLPAVRQYLFSLYECRYSVFFQSLAVVEQEMKKDWLFAPHYRYYVREMRIHAYSQLLESYRSLTLGYMAEAFGVGVEFIDQELSRFIAAGRLHCKIDKVNEIVETNRPDSKNWQYQETIKKGDLLLNRVQKLSRVINM
Chain L Sequence
LAVQKVVVHPLVLLSVVDHFNRIGKVGNQKRVVGVLLGSWQKKVLDVSNSFAVPFDEDDKDDSVWFLDHDYLENMYGMFKKVNARERIVGWYHTGPKLHKNDIAINELMKRYCPNSVLVIIDVKPKDLGLPTEAYISVE---------SKTFEHVTSEIGAEEAEEVGVEHLLRDIKDTTVGTLSQRITNQVHGLKGLNSKLLDIRSYLEKVATGKLPINHQIIYQLQDVFNLLPDVSLQEFVKAFYLKTNDQMVVVYLASLIRSVVALHNLINNKIANRDAEKKEGQEKEE
Chain L Sequence
EKKQPVDLGLLEEDDEFEEFPAEDW-------DAHVWEDNWDDDNVEDDFSNQLRAELEKHGYKME
sequence length 375,376,292,66
structure length 375,376,283,59
publication title An atomic structure of the human 26S proteasome.
pubmed doi rcsb
molecule tags Hydrolase
molecule keywords Proteasome subunit beta type-6
source organism Homo sapiens
missing residues U: 142-152 Y: 27-35
pdb deposition date2016-07-01
LinkProt deposition date2016-09-22

pfam database annotations

chain Pfam Accession CodePfam Family IdentifierPfam Description
LRUY PF00004 AAAATPase family associated with various cellular activities (AAA)
LRUY PF01399 PCIPCI domain
LRUY PF10602 RPN726S proteasome subunit RPN7
LRUY PF01398 JABJAB1/Mov34/MPN/PAD-1 ubiquitin protease
LRUY PF13012 MitMem_regMaintenance of mitochondrial structure and function
LRUY PF05160 DSS1_SEM1DSS1/SEM1 family
Image from the rcsb pdb (www.rcsb.org)
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LinkProt | Interdisciplinary Laboratory of Biological Systems Modelling