5GJQKfgh

Structure of the human 26s proteasome bound to usp14-ubal
Link type Probability Chain K piercings Chain f piercings Chain g piercings Chain h piercings
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Other Other 53% -39g -139g -418h -419h -28K -139K -2f -213f
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Other Other 53% -39g -139g -418h -419h -28K -139K -2f -213f
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Other Other 53% -39g -139g -418h -419h -28K -139K -2f -213f
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Other Other 53% -39g -139g -418h -419h -28K -139K -2f -213f
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Other Other 53% -39g -139g -418h -419h -28K -139K -2f -213f
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Other Other 53% -39g -139g -418h -419h -28K -139K -2f -213f
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Other Other 53% -39g -139g -418h -419h -28K -139K -2f -213f
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Other Other 53% -39g -139g -418h -419h -28K -139K -2f -213f
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Other Other 53% -39g -139g -418h -419h -28K -139K -2f -213f
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Other Other 53% -39g -139g -418h -419h -28K -139K -2f -213f
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Other Other 53% -39g -139g -418h -419h -28K -139K -2f -213f
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Other Other 53% -39g -139g -418h -419h -28K -139K -2f -213f
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Other Other 53% -39g -139g -418h -419h -28K -139K -2f -213f
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Other Other 53% -39g -139g -418h -419h -28K -139K -2f -213f
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Other Other 53% -39g -139g -418h -419h -28K -139K -2f -213f
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Other Other 53% -39g -139g -418h -419h -28K -139K -2f -213f
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Other Other 53% -39g -139g -418h -419h -28K -139K -2f -213f
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Other Other 53% -39g -139g -418h -419h -28K -139K -2f -213f
view details
Other Other 53% -39g -139g -418h -419h -28K -139K -2f -213f
view details
Other Other 53% -39g -139g -418h -419h -28K -139K -2f -213f
view details
Other Other 53% -39g -139g -418h -419h -28K -139K -2f -213f
view details
Other Other 53% -39g -139g -418h -419h -28K -139K -2f -213f
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Other Other 53% -39g -139g -418h -419h -28K -139K -2f -213f
view details
Other Other 53% -39g -139g -418h -419h -28K -139K -2f -213f
view details
Other Other 53% -39g -139g -418h -419h -28K -139K -2f -213f
view details
Other Other 53% -39g -139g -418h -419h -28K -139K -2f -213f
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Other Other 53% -39g -139g -418h -419h -28K -139K -2f -213f
Interpreting sequences
Chain K Sequence
DLYSRYKKLQQELEFLEVQEEYIKDEQKNLKKEFLHAQEEVKRIQSIPLVIGQFLEAVDQNTAIVGSTTGSNYYVRILSTIDRELLKPNASVALHKHSNALVDVLPPEADSSIMMLTSDQKPDVMYADIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAKAVAHHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFDAQTGADREVQRILLELLNQMDGFDQNVNVKVIMATNRADTLDPALLRPGRLDRKIEFPLPDRRQKRLIFSTITSKMNLSEEVDLEDYVARPDKISGADINSICQESGMLAVRENRYIVLAKDFEKAYKTVIKKDEQEHEFYK
Chain K Sequence
RFSPYVFNGGTILAIAGEDFAIVASDTRLSEGFSIHTRDSPKCYKLTDKTVIGCSGFHGDCLTLTKIIEARLKMYKHSNNKAMTTGAIAAMLSTILYSRRFFPYYVYNIIGGLDEEGKGAVYSFDPVGSYQRDSFKAGGSASAMLQPLLDNQVGFKNMQNVEHVPLSLDRAMRLVKDVFISAAERDVYTGDALRICIVTKEGIREETVSLRKD
Chain K Sequence
TQNPMVTGTSVLGVKFEGGVVIAADMLGSYGSLARFRNISRIMRVNNSTMLGASGDYADFQYLKQVLGQMVIDEELLGDGHSYSPRAIHSWLTRAMYSRRSKMNPLWNTMVIGGYADGESFLGYVDMLGVAYEAPSLATGYGAYLAQPLLREVLEKQPVLSQTEARDLVERCMRVLYYRDARSYNRFQIATVTEKGVEIEGPLSTETNWDIAHMIS
Chain K Sequence
SRGSSAGFDRHITIFSPEGRLYQVEYAFKAINQGGLTSVAVRGKDCAVIVTQKKVPDKLLDSSTVTHLFKITENIGCVMTGMTADSRSQVQRARYEAANWKYKYGYEIPVDMLCKRIADISQVYTQNAEMRPLGCCMILIGIDEEQGPQVYKCDPAGYYCGFKATAAGVKQTESTSFLEKKVKKKFDWTFEQTVETAITCLSTVLSIDFKPSEIEVGVVTVENPKFRILTEAEIDAHLVALAER
sequence length 380,213,216,244
structure length 380,213,216,244
publication title An atomic structure of the human 26S proteasome.
pubmed doi rcsb
molecule tags Hydrolase
molecule keywords Proteasome subunit beta type-6
source organism Homo sapiens
ec nomenclature ec 3.4.25.1: Proteasome endopeptidase complex.
ec 3.4.25.1: Proteasome endopeptidase complex.
ec 3.4.25.1: Proteasome endopeptidase complex.
pdb deposition date2016-07-01
LinkProt deposition date2016-09-22

pfam database annotations

chain Pfam Accession CodePfam Family IdentifierPfam Description
Kfgh PF00004 AAAATPase family associated with various cellular activities (AAA)
Kfgh PF00227 ProteasomeProteasome subunit
Kfgh PF00227 ProteasomeProteasome subunit
Kfgh PF00227 ProteasomeProteasome subunit
Kfgh PF10584 Proteasome_A_NProteasome subunit A N-terminal signature
Image from the rcsb pdb (www.rcsb.org)
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LinkProt | Interdisciplinary Laboratory of Biological Systems Modelling