5GJQKYho

Structure of the human 26s proteasome bound to usp14-ubal
Y: 27-35
Link type Probability Chain K piercings Chain Y piercings Chain h piercings Chain o piercings
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Other Other 33% +69Y +69Y +89h +146h -246o -246o -413K +246K +68Y
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Other Other 33% +69Y +69Y +89h +146h -246o -246o -413K +246K +68Y
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Other Other 33% +69Y +69Y +89h +146h -246o -246o -413K +246K +68Y
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Other Other 33% +69Y +69Y +89h +146h -246o -246o -413K +246K +68Y
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Other Other 33% +69Y +69Y +89h +146h -246o -246o -413K +246K +68Y
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Other Other 33% +69Y +69Y +89h +146h -246o -246o -413K +246K +68Y
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Other Other 33% +69Y +69Y +89h +146h -246o -246o -413K +246K +68Y
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Other Other 33% +69Y +69Y +89h +146h -246o -246o -413K +246K +68Y
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Other Other 33% +69Y +69Y +89h +146h -246o -246o -413K +246K +68Y
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Other Other 33% +69Y +69Y +89h +146h -246o -246o -413K +246K +68Y
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Other Other 33% +69Y +69Y +89h +146h -246o -246o -413K +246K +68Y
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Other Other 33% +69Y +69Y +89h +146h -246o -246o -413K +246K +68Y
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Other Other 33% +69Y +69Y +89h +146h -246o -246o -413K +246K +68Y
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Other Other 33% +69Y +69Y +89h +146h -246o -246o -413K +246K +68Y
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Other Other 33% +69Y +69Y +89h +146h -246o -246o -413K +246K +68Y
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Other Other 33% +69Y +69Y +89h +146h -246o -246o -413K +246K +68Y
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Other Other 33% +69Y +69Y +89h +146h -246o -246o -413K +246K +68Y
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Other Other 33% +69Y +69Y +89h +146h -246o -246o -413K +246K +68Y
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Other Other 33% +69Y +69Y +89h +146h -246o -246o -413K +246K +68Y
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Other Other 33% +69Y +69Y +89h +146h -246o -246o -413K +246K +68Y
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Other Other 33% +69Y +69Y +89h +146h -246o -246o -413K +246K +68Y
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Other Other 33% +69Y +69Y +89h +146h -246o -246o -413K +246K +68Y
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Other Other 33% +69Y +69Y +89h +146h -246o -246o -413K +246K +68Y
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Other Other 33% +69Y +69Y +89h +146h -246o -246o -413K +246K +68Y
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Other Other 33% +69Y +69Y +89h +146h -246o -246o -413K +246K +68Y
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Other Other 33% +69Y +69Y +89h +146h -246o -246o -413K +246K +68Y
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Other Other 33% +69Y +69Y +89h +146h -246o -246o -413K +246K +68Y
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Other Other 33% +69Y +69Y +89h +146h -246o -246o -413K +246K +68Y
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Other Other 33% +69Y +69Y +89h +146h -246o -246o -413K +246K +68Y
Interpreting sequences
Chain K Sequence
DLYSRYKKLQQELEFLEVQEEYIKDEQKNLKKEFLHAQEEVKRIQSIPLVIGQFLEAVDQNTAIVGSTTGSNYYVRILSTIDRELLKPNASVALHKHSNALVDVLPPEADSSIMMLTSDQKPDVMYADIGGMDIQKQEVREAVELPLTHFELYKQIGIDPPRGVLMYGPPGCGKTMLAKAVAHHTTAAFIRVVGSEFVQKYLGEGPRMVRDVFRLAKENAPAIIFIDEIDAIATKRFDAQTGADREVQRILLELLNQMDGFDQNVNVKVIMATNRADTLDPALLRPGRLDRKIEFPLPDRRQKRLIFSTITSKMNLSEEVDLEDYVARPDKISGADINSICQESGMLAVRENRYIVLAKDFEKAYKTVIKKDEQEHEFYK
Chain K Sequence
EKKQPVDLGLLEEDDEFEEFPAEDW-------DAHVWEDNWDDDNVEDDFSNQLRAELEKHGYKME
Chain K Sequence
SRGSSAGFDRHITIFSPEGRLYQVEYAFKAINQGGLTSVAVRGKDCAVIVTQKKVPDKLLDSSTVTHLFKITENIGCVMTGMTADSRSQVQRARYEAANWKYKYGYEIPVDMLCKRIADISQVYTQNAEMRPLGCCMILIGIDEEQGPQVYKCDPAGYYCGFKATAAGVKQTESTSFLEKKVKKKFDWTFEQTVETAITCLSTVLSIDFKPSEIEVGVVTVENPKFRILTEAEIDAHLVALAER
Chain K Sequence
TTIMAVQFDGGVVLGADSRTTTGSYIANRVTDKLTPIHDRIFCCRSGSAADTQAVADAVTYQLGFHSIELNEPPLVHTAASLFKEMCYRYREDLMAGIIIAGWDPQEGGQVYSVPMGGMMVRQSFAIGGSGSSYIYGYVDATYREGMTKEECLQFTANALALAMERDGSSGGVIRLAAIAESGVERQVLLGDQIPKFAVATL
sequence length 380,66,244,202
structure length 380,59,244,202
publication title An atomic structure of the human 26S proteasome.
pubmed doi rcsb
molecule tags Hydrolase
molecule keywords Proteasome subunit beta type-6
source organism Homo sapiens
missing residues Y: 27-35
ec nomenclature ec 3.4.25.1: Proteasome endopeptidase complex.
ec 3.4.25.1: Proteasome endopeptidase complex.
pdb deposition date2016-07-01
LinkProt deposition date2016-09-22

pfam database annotations

chain Pfam Accession CodePfam Family IdentifierPfam Description
KYho PF00004 AAAATPase family associated with various cellular activities (AAA)
KYho PF05160 DSS1_SEM1DSS1/SEM1 family
KYho PF00227 ProteasomeProteasome subunit
KYho PF10584 Proteasome_A_NProteasome subunit A N-terminal signature
KYho PF00227 ProteasomeProteasome subunit
Image from the rcsb pdb (www.rcsb.org)
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LinkProt | Interdisciplinary Laboratory of Biological Systems Modelling