5GJQHIOU

Structure of the human 26s proteasome bound to usp14-ubal
H: 72-80 I: 84-91 O: 54-57 U: 142-152
Link type Probability Chain H piercings Chain I piercings Chain O piercings Chain U piercings
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Other Other 32% -194I +220I -429I -434O -376U -157H +191H -207H +376H +128I
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Other Other 32% -194I +220I -429I -434O -376U -157H +191H -207H +376H +128I
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Other Other 32% -194I +220I -429I -434O -376U -157H +191H -207H +376H +128I
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Other Other 32% -194I +220I -429I -434O -376U -157H +191H -207H +376H +128I
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Other Other 32% -194I +220I -429I -434O -376U -157H +191H -207H +376H +128I
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Other Other 32% -194I +220I -429I -434O -376U -157H +191H -207H +376H +128I
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Other Other 32% -194I +220I -429I -434O -376U -157H +191H -207H +376H +128I
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Other Other 32% -194I +220I -429I -434O -376U -157H +191H -207H +376H +128I
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Other Other 32% -194I +220I -429I -434O -376U -157H +191H -207H +376H +128I
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Other Other 32% -194I +220I -429I -434O -376U -157H +191H -207H +376H +128I
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Other Other 32% -194I +220I -429I -434O -376U -157H +191H -207H +376H +128I
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Other Other 32% -194I +220I -429I -434O -376U -157H +191H -207H +376H +128I
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Other Other 32% -194I +220I -429I -434O -376U -157H +191H -207H +376H +128I
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Other Other 32% -194I +220I -429I -434O -376U -157H +191H -207H +376H +128I
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Other Other 32% -194I +220I -429I -434O -376U -157H +191H -207H +376H +128I
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Other Other 32% -194I +220I -429I -434O -376U -157H +191H -207H +376H +128I
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Other Other 32% -194I +220I -429I -434O -376U -157H +191H -207H +376H +128I
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Other Other 32% -194I +220I -429I -434O -376U -157H +191H -207H +376H +128I
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Other Other 32% -194I +220I -429I -434O -376U -157H +191H -207H +376H +128I
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Other Other 32% -194I +220I -429I -434O -376U -157H +191H -207H +376H +128I
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Other Other 32% -194I +220I -429I -434O -376U -157H +191H -207H +376H +128I
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Other Other 32% -194I +220I -429I -434O -376U -157H +191H -207H +376H +128I
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Other Other 32% -194I +220I -429I -434O -376U -157H +191H -207H +376H +128I
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Other Other 32% -194I +220I -429I -434O -376U -157H +191H -207H +376H +128I
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Other Other 32% -194I +220I -429I -434O -376U -157H +191H -207H +376H +128I
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Other Other 32% -194I +220I -429I -434O -376U -157H +191H -207H +376H +128I
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Other Other 32% -194I +220I -429I -434O -376U -157H +191H -207H +376H +128I
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Other Other 32% -194I +220I -429I -434O -376U -157H +191H -207H +376H +128I
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Other Other 32% -194I +220I -429I -434O -376U -157H +191H -207H +376H +128I
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Other Other 32% -194I +220I -429I -434O -376U -157H +191H -207H +376H +128I
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Other Other 32% -194I +220I -429I -434O -376U -157H +191H -207H +376H +128I
view details
Other Other 32% -194I +220I -429I -434O -376U -157H +191H -207H +376H +128I
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Other Other 32% -194I +220I -429I -434O -376U -157H +191H -207H +376H +128I
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Other Other 32% -194I +220I -429I -434O -376U -157H +191H -207H +376H +128I
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Other Other 32% -194I +220I -429I -434O -376U -157H +191H -207H +376H +128I
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Other Other 32% -194I +220I -429I -434O -376U -157H +191H -207H +376H +128I
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Other Other 32% -194I +220I -429I -434O -376U -157H +191H -207H +376H +128I
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Other Other 32% -194I +220I -429I -434O -376U -157H +191H -207H +376H +128I
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Other Other 32% -194I +220I -429I -434O -376U -157H +191H -207H +376H +128I
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Other Other 32% -194I +220I -429I -434O -376U -157H +191H -207H +376H +128I
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Other Other 32% -194I +220I -429I -434O -376U -157H +191H -207H +376H +128I
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Other Other 32% -194I +220I -429I -434O -376U -157H +191H -207H +376H +128I
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Other Other 32% -194I +220I -429I -434O -376U -157H +191H -207H +376H +128I
Interpreting sequences
Chain H Sequence
QVEDDIQQLLKKINELTGIKESDTGL-------LAADKQTLQSEQPLQVARCTKIINADSEDPKYIINVKQFAKFVVDLSDQVAPTDIEEGMRVGVDRNKYQIHIPLPPKIDPTVTMMQVEEKPDVTYSDVGGCKEQIEKLREVVETPLLHPERFVNLGIEPPKGVLLFGPPGTGKTLCARAVANRTDACFIRVIGSELVQKYVGEGARMVRELFEMARTKKACLIFFDEIDAIGGARFDDGAGGDNEVQRTMLELINQLDGFDPRGNIKVLMATNRPDTLDPALMRPGRLDRKIEFSLPDLEGRTHIFKIHARSMSVERDIRFELLARLCPNSTGAEIRSVCTEAGMFAIRARRKIATEKDFLEAVNKVIKSYAKFSATPRYMTYN
Chain H Sequence
LERIKDYLLMEEEFIRNQEQ------KQEEERSKVDDLRGTPMSVGTLEEIIDDNHAIVSTSVGSEHYVSILSFVDKDLLEPGCSVLLNHKVHAVIGVLMDDTDPLVTVMKVEKAPQETYADIGGLDNQIQEIKESVELPLTHPEYYEEMGIKPPKGVILYGPPGTGKTLLAKAVANQTSATFLRVVGSELIQKYLGDGPKLVRELFRVAEEHAPSIVFIDEIDAIGTKRYDSNSGGEREIQRTMLELLNQLDGFDSRGDVKVIMATNRIETLDPALIRPGRIDRKIEFPLPDEKTKKRIFQIHTSRMTLADDVTLDDLIMAKDDLSGADIKAICTEAGLMALRERRMKVTNEDFKKSKENVLYK
Chain H Sequence
DVPGFLQQSQNSGPGQPAVWHRLEELYTKKLWHQLTLQVLDFVQDPCFAQGD--IKLYENFISEFEHRVNPLSLVEIILHVVRQMTDPNVALTFLEKTREKVKSSDEAVILCKTAIGALKLNIGDLQVTKETIEDVEEMLNNLPGVTSVHSRFYDLSSKYYQTIGNHASYYKDALRFLGCVDIKDLPVSEQQERAFTLGLAGLLGEGVFNFGELLMHPVLESLRNTDRQWLIDTLYAFNSGNVERFQTLKTAWGQQPDLAANEAQLLRKIQLLCLMEMTFTRPANHRQLTFEEIAKSAKITVNEVELLVMKALSVGLVKGSIDEVDKRVHMTWVQPRVLDLQQIKGMKDRLEFWCTDVKSMEMLVEHQAHDILT
Chain H Sequence
LAVQKVVVHPLVLLSVVDHFNRIGKVGNQKRVVGVLLGSWQKKVLDVSNSFAVPFDEDDKDDSVWFLDHDYLENMYGMFKKVNARERIVGWYHTGPKLHKNDIAINELMKRYCPNSVLVIIDVKPKDLGLPTEAYISVE---------SKTFEHVTSEIGAEEAEEVGVEHLLRDIKDTTVGTLSQRITNQVHGLKGLNSKLLDIRSYLEKVATGKLPINHQIIYQLQDVFNLLPDVSLQEFVKAFYLKTNDQMVVVYLASLIRSVVALHNLINNKIANRDAEKKEGQEKEE
sequence length 387,365,374,292
structure length 380,359,372,283
publication title An atomic structure of the human 26S proteasome.
pubmed doi rcsb
molecule tags Hydrolase
molecule keywords Proteasome subunit beta type-6
source organism Homo sapiens
missing residues H: 72-80 I: 84-91 O: 54-57 U: 142-152
pdb deposition date2016-07-01
LinkProt deposition date2016-09-22

pfam database annotations

chain Pfam Accession CodePfam Family IdentifierPfam Description
HIOU PF00004 AAAATPase family associated with various cellular activities (AAA)
HIOU PF00004 AAAATPase family associated with various cellular activities (AAA)
HIOU PF01399 PCIPCI domain
HIOU PF01398 JABJAB1/Mov34/MPN/PAD-1 ubiquitin protease
HIOU PF13012 MitMem_regMaintenance of mitochondrial structure and function
Image from the rcsb pdb (www.rcsb.org)
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LinkProt | Interdisciplinary Laboratory of Biological Systems Modelling