5GJQDGcd

Structure of the human 26s proteasome bound to usp14-ubal
Link type Probability Chain D piercings Chain G piercings Chain c piercings Chain d piercings
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Other Other 31% +2c -252c
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Other Other 31% +2c -252c
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Other Other 31% +2c -252c
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Other Other 31% +2c -252c
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Other Other 31% +2c -252c
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Other Other 31% +2c -252c
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Other Other 31% +2c -252c
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Other Other 31% +2c -252c
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Other Other 31% +2c -252c
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Other Other 31% +2c -252c
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Other Other 31% +2c -252c
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Other Other 31% +2c -252c
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Other Other 31% +2c -252c
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Other Other 31% +2c -252c
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Other Other 31% +2c -252c
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Other Other 31% +2c -252c
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Other Other 31% +2c -252c
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Other Other 31% +2c -252c
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Other Other 31% +2c -252c
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Other Other 31% +2c -252c
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Other Other 31% +2c -252c
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Other Other 31% +2c -252c
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Other Other 31% +2c -252c
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Other Other 31% +2c -252c
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Other Other 31% +2c -252c
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Other Other 31% +2c -252c
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Other Other 31% +2c -252c
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Other Other 31% +2c -252c
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Other Other 31% +2c -252c
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Other Other 31% +2c -252c
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Other Other 31% +2c -252c
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Other Other 31% +2c -252c
Interpreting sequences
Chain D Sequence
SRRYDSRTTIFSPEGRLYQVEYAMEAIGHAGTCLGILANDGVLLAAERRNIHKLLDEVFFSEKIYKLNEDMACSVAGITSDANVLTNELRLIAQRYLLQYQEPIPCEQLVTALCDIKQAYTQFGGKRPFGVSLLYIGWDKHYGFQLYQSDPSGNYGGWKATCIGNNSAAAVSMLKQDYKEGEMTLKSALALAIKVLNKTMDVSKLSAEKVEIATLTRENGKTVIRVLKQKEVEQLIKKHEEEEAKAEREK
Chain D Sequence
NQYDNDVTVWSPQGRIHQIEYAMEAVKQGSATVGLKSKTHAVLVALKRAQSELAAHQKKILHVDNHIGISIAGLTADARLLCNFMRQECLDSRFVFDRPLPVSRLVSLIGSKTQIPTQRYGRRPYGVGLLIAGYDDMGPHIFQTCPSANYFDCRAMSIGARSQSARTYLERHMSEFMECNLNELVKHGLRALRETLPAEQDLTTKNVSIGIVGKDLEFTIYDDDDVSPFLEGLEERPQ
Chain D Sequence
SIMSYNGGAVMAMKGKNCVAIAADRRFGIQAQMVTTDFQKIFPMGDRLYIGLAGLATDVQTVAQRLKFRLNLYELKEGRQIKPYTLMSMVANLLYEKRFGPYYTEPVIAGLDPKTFKPFICSLDLIGCPMVTDDFVVSGTCAEQMYGMCESLWEPNMDPDHLFETISQAMLNAVDRDAVSGMGVIVHIIEKDKITTRTLKARMD
Chain D Sequence
MEYLIGIQGPDYVLVASDRVAASNIVQMKDDHDKMFKMSEKILLLCVGEAGDTVQFAEYIQKNVQLYKMRNGYELSPTAAANFTRRNLADCLRSRTPYHVNLLLAGYDEHEGPALYYMDYLAALAKAPFAAHGYGAFLTLSILDRYYTPTISRERAVELLRKCLEELQKRFILNLPTFSVRIIDKNGIHDLDNISFPKQ
sequence length 250,238,204,199
structure length 250,238,204,199
publication title An atomic structure of the human 26S proteasome.
pubmed doi rcsb
molecule tags Hydrolase
molecule keywords Proteasome subunit beta type-6
source organism Homo sapiens
ec nomenclature ec 3.4.25.1: Proteasome endopeptidase complex.
ec 3.4.25.1: Proteasome endopeptidase complex.
ec 3.4.25.1: Proteasome endopeptidase complex.
ec 3.4.25.1: Proteasome endopeptidase complex.
pdb deposition date2016-07-01
LinkProt deposition date2016-09-22

pfam database annotations

chain Pfam Accession CodePfam Family IdentifierPfam Description
DGcd PF00227 ProteasomeProteasome subunit
DGcd PF10584 Proteasome_A_NProteasome subunit A N-terminal signature
DGcd PF00227 ProteasomeProteasome subunit
DGcd PF10584 Proteasome_A_NProteasome subunit A N-terminal signature
DGcd PF00227 ProteasomeProteasome subunit
DGcd PF00227 ProteasomeProteasome subunit
Image from the rcsb pdb (www.rcsb.org)
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LinkProt | Interdisciplinary Laboratory of Biological Systems Modelling