| Link type | Probability | Chain B piercings | Chain C piercings | Chain D piercings | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
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Unlink | 26% | -105B +116B -105C +115C -305C +317C | ||||||||||
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Unlink | 26% | -105B +116B -105C +115C -305C +317C | ||||||||||
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Unlink | 26% | -105B +116B -105C +115C -305C +317C | ||||||||||
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Unlink | 26% | -105B +116B -105C +115C -305C +317C | ||||||||||
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Unlink | 26% | -105B +116B -105C +115C -305C +317C | ||||||||||
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Unlink | 26% | -105B +116B -105C +115C -305C +317C | ||||||||||
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Unlink | 26% | -105B +116B -105C +115C -305C +317C | ||||||||||
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Unlink | 26% | -105B +116B -105C +115C -305C +317C | ||||||||||
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Unlink | 26% | -105B +116B -105C +115C -305C +317C | ||||||||||
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Unlink | 26% | -105B +116B -105C +115C -305C +317C | ||||||||||
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Unlink | 26% | -105B +116B -105C +115C -305C +317C | ||||||||||
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Unlink | 26% | -105B +116B -105C +115C -305C +317C | ||||||||||
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Unlink | 26% | -105B +116B -105C +115C -305C +317C | ||||||||||
| view details |
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Unlink | 26% | -105B +116B -105C +115C -305C +317C | ||||||||||
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Unlink | 26% | -105B +116B -105C +115C -305C +317C | ||||||||||
| view details |
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Unlink | 26% | -105B +116B -105C +115C -305C +317C | ||||||||||
| view details |
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Unlink | 26% | -105B +116B -105C +115C -305C +317C | ||||||||||
| view details |
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Unlink | 26% | -105B +116B -105C +115C -305C +317C | ||||||||||
| view details |
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Unlink | 26% | -105B +116B -105C +115C -305C +317C | ||||||||||
| view details |
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Unlink | 26% | -105B +116B -105C +115C -305C +317C | ||||||||||
| view details |
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Unlink | 26% | -105B +116B -105C +115C -305C +317C | ||||||||||
| view details |
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Unlink | 26% | -105B +116B -105C +115C -305C +317C | ||||||||||
| view details |
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Unlink | 26% | -105B +116B -105C +115C -305C +317C | ||||||||||
| view details |
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Unlink | 26% | -105B +116B -105C +115C -305C +317C | ||||||||||
| view details |
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Unlink | 26% | -105B +116B -105C +115C -305C +317C | ||||||||||
| view details |
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Unlink | 26% | -105B +116B -105C +115C -305C +317C | ||||||||||
| view details |
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Unlink | 26% | -105B +116B -105C +115C -305C +317C | ||||||||||
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Unlink | 26% | -105B +116B -105C +115C -305C +317C | ||||||||||
Chain B Sequence |
VRLPFSGFRLQKVLRESARDKIIFLHGKVN---------DAVVILEKTPFQVEQVAQLLTGSPELQLQFSNDIYSTYHLFPPRQLNDVKTTVVYPATEKHLQKYLRQDLRLIRETGDDYRNITLPHLESQSLSIQWVYNILDKKAEADRIVFENPDPSDGFVLIPDLKWNQQQLDDLYLIAICHRRGIRSLRDLTPEHLPLLRNILHQGQEAILQRYRMKGDHLRVYLHYLPSYYHLHVHFTALGFEAPGSGVERAHLLAEVIENLECDPRHYQQRTLTFALRADDPLLKLLQEAQQ |
Chain B Sequence |
PVRLPFSGFRLQKVLRESARDKIIFLHGK---------GEDAVVILEKTPFQVEQVAQLLTGSPELQLQFSNDIYSTYHLFPPRQLNDVKTTVVYPATEKHLQKYLRQDLRLIRETGDDYRNITLPHLESQSLSIQWVYNILDKKAEADRIVFENPDPSDGFVLIPDLKWNQQQLDDLYLIAICHRRGIRSLRDLTPEHLPLLRNILHQGQEAILQRYRMKGDHLRVYLHYLPSYYHLHVHFTALGFEAPGSGVERAHLLAEVIENLECDPRHYQQRTLTFALRADDPLLKLLQEAQQ |
Chain B Sequence |
APVRLPFSGFRLQKVLRESARDKIIFLHGKVNE----GDGEDAVVILEKTPFQVEQVAQLL---PELQLQFS-DIYSTYHLFPPRQLNDVKTTVVYPATEKHLQKYLRQDLRLIRETGDDYRNITLPHLESQSLSIQWVYNILDKKAEADRIVFENPDPSDGFVLIPDLKWNQQQLDDLYLIAICHRRGIRSLRDLTPEHLPLLRNILHQGQEAILQRYRMKGDHLRVYLHYLPSYYHLHVHFTALGFEAPGSGVERAHLLAEVIENLECDPRHYQQRTLTFALRADDPLLKLLQEAQQS |
| sequence length | 297,298,300 |
| structure length | 288,289,292 |
| publication title |
Crystal structures of human DcpS in ligand-free and m7GDP-bound forms suggest a dynamic mechanism for scavenger mRNA decapping.
pubmed doi rcsb |
| molecule tags | Chaperone |
| molecule keywords | heat shock-like protein 1 |
| source organism | Homo sapiens |
| missing residues | B: 69-79 C: 67-77 D: 70-75,98-102,109-111 |
| ec nomenclature |
ec 3.6.1.59: 5'-(N(7)-methyl 5'-triphosphoguanosine)-[mRNA] diphosphatase. ec 3.6.1.59: 5'-(N(7)-methyl 5'-triphosphoguanosine)-[mRNA] diphosphatase. ec 3.6.1.59: 5'-(N(7)-methyl 5'-triphosphoguanosine)-[mRNA] diphosphatase. |
| pdb deposition date | 2004-10-04 |
| LinkProt deposition date | 2016-10-22 |
| chain | Pfam Accession Code | Pfam Family Identifier | Pfam Description |
|---|---|---|---|
| BCD | PF05652 | DcpS | Scavenger mRNA decapping enzyme (DcpS) N-terminal |
| BCD | PF11969 | DcpS_C | Scavenger mRNA decapping enzyme C-term binding |
| BCD | PF05652 | DcpS | Scavenger mRNA decapping enzyme (DcpS) N-terminal |
| BCD | PF11969 | DcpS_C | Scavenger mRNA decapping enzyme C-term binding |
| BCD | PF05652 | DcpS | Scavenger mRNA decapping enzyme (DcpS) N-terminal |
| BCD | PF11969 | DcpS_C | Scavenger mRNA decapping enzyme C-term binding |
Image from the rcsb pdb (www.rcsb.org)cath code
| Class | Architecture | Topology | Homology | Domain |
|---|---|---|---|---|---|
| Alpha Beta | 2-Layer Sandwich | HIT family, subunit A | HIT family, subunit A | ||
| Alpha Beta | 2-Layer Sandwich | mRNA decapping enzyme DcpS N-terminal fold | mRNA decapping enzyme DcpS N-terminal domain | ||
| Alpha Beta | 2-Layer Sandwich | HIT family, subunit A | HIT family, subunit A | ||
| Alpha Beta | 2-Layer Sandwich | mRNA decapping enzyme DcpS N-terminal fold | mRNA decapping enzyme DcpS N-terminal domain |
#chains in the LinkProt database with same CATH superfamily 1XMM AB; 1XMM ABC; 1XMM ABD; 1XMM CD; 1XMM BC; 1XMM BD; 1XMM BCD; 1XMM ABCD; #chains in the LinkProt database with same CATH topology 1XMM AB; 1XMM ABC; 1XMM ABD; 1XMM CD; 1XMM BC; 1XMM BD; 1XMM BCD; 1XMM ABCD; #chains in the LinkProt database with same CATH homology 1XMM AB; 1XMM ABC; 1XMM ABD; 1XMM CD; 1XMM BC; 1XMM BD; 1XMM BCD; 1XMM ABCD;
#similar chains in the LinkProt database (?% sequence similarity) ...loading similar chains, please wait... #similar chains, but unlinked ...loading similar chains, please wait... #similar chains in the pdb database (?% sequence similarity) ...loading similar chains, please wait...
