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Unlink | 15% | -46B +81B -104B +117B | ||||||||||
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Unlink | 15% | -46B +81B -104B +117B | ||||||||||
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Unlink | 15% | -46B +81B -104B +117B | ||||||||||
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Unlink | 15% | -46B +81B -104B +117B | ||||||||||
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Unlink | 15% | -46B +81B -104B +117B | ||||||||||
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Unlink | 15% | -46B +81B -104B +117B | ||||||||||
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Unlink | 15% | -46B +81B -104B +117B | ||||||||||
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Unlink | 15% | -46B +81B -104B +117B | ||||||||||
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Unlink | 15% | -46B +81B -104B +117B | ||||||||||
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Unlink | 15% | -46B +81B -104B +117B | ||||||||||
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Unlink | 15% | -46B +81B -104B +117B | ||||||||||
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Unlink | 15% | -46B +81B -104B +117B | ||||||||||
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Unlink | 15% | -46B +81B -104B +117B | ||||||||||
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Unlink | 15% | -46B +81B -104B +117B | ||||||||||
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Unlink | 15% | -46B +81B -104B +117B | ||||||||||
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Unlink | 15% | -46B +81B -104B +117B | ||||||||||
Chain A Sequence |
VRLPFSGFRLQKVLRESARDKIIFLHGKV---------EDAVVILEKTPFQVEQVAQLLTGSPELQLQFSN-IYSTYHLFPPRQLNDVKTTVVYPATEKHLQKYLRQDLRLIRETGDDYRNITLPHLESQSLSIQWVYNILDKKAEADRIVFENPDPSDGFVLIPDLKWNQQQLDDLYLIAICHRRGIRSLRDLTPEHLPLLRNILHQGQEAILQRYRMKGDHLRVYLHYLPSYYHLHVHFTALGFEAPGSGVERAHLLAEVIENLECDPRHYQQRTLTFALRADDPLLKLLQEAQQ |
Chain A Sequence |
VRLPFSGFRLQKVLRESARDKIIFLHGKVN---------DAVVILEKTPFQVEQVAQLLTGSPELQLQFSNDIYSTYHLFPPRQLNDVKTTVVYPATEKHLQKYLRQDLRLIRETGDDYRNITLPHLESQSLSIQWVYNILDKKAEADRIVFENPDPSDGFVLIPDLKWNQQQLDDLYLIAICHRRGIRSLRDLTPEHLPLLRNILHQGQEAILQRYRMKGDHLRVYLHYLPSYYHLHVHFTALGFEAPGSGVERAHLLAEVIENLECDPRHYQQRTLTFALRADDPLLKLLQEAQQ |
Chain A Sequence |
PVRLPFSGFRLQKVLRESARDKIIFLHGK---------GEDAVVILEKTPFQVEQVAQLLTGSPELQLQFSNDIYSTYHLFPPRQLNDVKTTVVYPATEKHLQKYLRQDLRLIRETGDDYRNITLPHLESQSLSIQWVYNILDKKAEADRIVFENPDPSDGFVLIPDLKWNQQQLDDLYLIAICHRRGIRSLRDLTPEHLPLLRNILHQGQEAILQRYRMKGDHLRVYLHYLPSYYHLHVHFTALGFEAPGSGVERAHLLAEVIENLECDPRHYQQRTLTFALRADDPLLKLLQEAQQ |
| sequence length | 297,297,298 |
| structure length | 287,288,289 |
| publication title |
Crystal structures of human DcpS in ligand-free and m7GDP-bound forms suggest a dynamic mechanism for scavenger mRNA decapping.
pubmed doi rcsb |
| molecule tags | Chaperone |
| molecule keywords | heat shock-like protein 1 |
| source organism | Homo sapiens |
| missing residues | A: 68-78,110-112 B: 69-79 C: 67-77 |
| ec nomenclature |
ec 3.6.1.59: 5'-(N(7)-methyl 5'-triphosphoguanosine)-[mRNA] diphosphatase. ec 3.6.1.59: 5'-(N(7)-methyl 5'-triphosphoguanosine)-[mRNA] diphosphatase. ec 3.6.1.59: 5'-(N(7)-methyl 5'-triphosphoguanosine)-[mRNA] diphosphatase. |
| pdb deposition date | 2004-10-04 |
| LinkProt deposition date | 2016-10-22 |
| chain | Pfam Accession Code | Pfam Family Identifier | Pfam Description |
|---|---|---|---|
| ABC | PF05652 | DcpS | Scavenger mRNA decapping enzyme (DcpS) N-terminal |
| ABC | PF11969 | DcpS_C | Scavenger mRNA decapping enzyme C-term binding |
| ABC | PF05652 | DcpS | Scavenger mRNA decapping enzyme (DcpS) N-terminal |
| ABC | PF11969 | DcpS_C | Scavenger mRNA decapping enzyme C-term binding |
| ABC | PF05652 | DcpS | Scavenger mRNA decapping enzyme (DcpS) N-terminal |
| ABC | PF11969 | DcpS_C | Scavenger mRNA decapping enzyme C-term binding |
Image from the rcsb pdb (www.rcsb.org)cath code
| Class | Architecture | Topology | Homology | Domain |
|---|---|---|---|---|---|
| Alpha Beta | 2-Layer Sandwich | HIT family, subunit A | HIT family, subunit A | ||
| Alpha Beta | 2-Layer Sandwich | mRNA decapping enzyme DcpS N-terminal fold | mRNA decapping enzyme DcpS N-terminal domain | ||
| Alpha Beta | 2-Layer Sandwich | HIT family, subunit A | HIT family, subunit A | ||
| Alpha Beta | 2-Layer Sandwich | mRNA decapping enzyme DcpS N-terminal fold | mRNA decapping enzyme DcpS N-terminal domain |
#chains in the LinkProt database with same CATH superfamily 1XMM AB; 1XMM ABC; 1XMM ABD; 1XMM CD; 1XMM BC; 1XMM BD; 1XMM BCD; 1XMM ABCD; #chains in the LinkProt database with same CATH topology 1XMM AB; 1XMM ABC; 1XMM ABD; 1XMM CD; 1XMM BC; 1XMM BD; 1XMM BCD; 1XMM ABCD; #chains in the LinkProt database with same CATH homology 1XMM AB; 1XMM ABC; 1XMM ABD; 1XMM CD; 1XMM BC; 1XMM BD; 1XMM BCD; 1XMM ABCD;
#similar chains in the LinkProt database (?% sequence similarity) ...loading similar chains, please wait... #similar chains, but unlinked ...loading similar chains, please wait... #similar chains in the pdb database (?% sequence similarity) ...loading similar chains, please wait...
