Link type | Probability | Chain A piercings | Chain D piercings | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
view details | Hopf.1 | 32% | +45D -57D -212D +222D +427D | +20A +45A -428A | |||||||||
view details | Hopf.1 | 32% | +45D -57D -212D +222D +427D | +20A +45A -428A | |||||||||
view details | Hopf.1 | 32% | +45D -57D -212D +222D +427D | +20A +45A -428A | |||||||||
view details | Hopf.1 | 32% | +45D -57D -212D +222D +427D | +20A +45A -428A | |||||||||
view details | Hopf.1 | 32% | +45D -57D -212D +222D +427D | +20A +45A -428A | |||||||||
view details | Hopf.1 | 32% | +45D -57D -212D +222D +427D | +20A +45A -428A | |||||||||
view details | Hopf.1 | 32% | +45D -57D -212D +222D +427D | +20A +45A -428A | |||||||||
view details | Hopf.1 | 32% | +45D -57D -212D +222D +427D | +20A +45A -428A | |||||||||
view details | Hopf.1 | 32% | +45D -57D -212D +222D +427D | +20A +45A -428A | |||||||||
view details | Hopf.1 | 32% | +45D -57D -212D +222D +427D | +20A +45A -428A | |||||||||
view details | Hopf.1 | 32% | +45D -57D -212D +222D +427D | +20A +45A -428A | |||||||||
view details | Hopf.1 | 32% | +45D -57D -212D +222D +427D | +20A +45A -428A | |||||||||
view details | Hopf.1 | 32% | +45D -57D -212D +222D +427D | +20A +45A -428A | |||||||||
view details | Hopf.1 | 32% | +45D -57D -212D +222D +427D | +20A +45A -428A | |||||||||
view details | Hopf.1 | 32% | +45D -57D -212D +222D +427D | +20A +45A -428A | |||||||||
view details | Hopf.1 | 32% | +45D -57D -212D +222D +427D | +20A +45A -428A | |||||||||
view details | Hopf.1 | 32% | +45D -57D -212D +222D +427D | +20A +45A -428A | |||||||||
view details | Hopf.1 | 32% | +45D -57D -212D +222D +427D | +20A +45A -428A | |||||||||
view details | Hopf.1 | 32% | +45D -57D -212D +222D +427D | +20A +45A -428A |
Chain A Sequence |
ASVVGTPKSAEQIQQEWDTNPRWKDVTRTYSAEDVVALQGSVVEEHTLARRGAEVLWEQLHDLEWVNALGALTGNMAVQQVRAGLKAIYLSGWQVAGDANLSGHTYPDQSLYPANSVPQVVRRINNALQRADQIAKIEGDTSVENWLAPIVADGEAGFGGALNVYELQKALIAAGVAGSHWEDQLASEKKSGHLGGKVLIPTQQHIRTLTSARLAADVADVPTVVIARTDAEAATLITSDVDERDQPFITGERTREGFYRTKNGIEPCIARAKAYAPFADLIWMETGTPDLEAARQFSEAVKAEYPDQMLAYNCSPSFNWKKHLDDATIAKFQKELAAMGFKFQFITLAGFHALNYSMFDLAYGYAQNQMSAYVELQEREFAAEERGYTATKHQREVGAGYFDRIATTVDPNSSTTALTGSTEEGQF |
Chain A Sequence |
ASVVGTPKSAEQIQQEWDTNPRWKDVTRTYSAEDVVALQGSVVEEHTLARRGAEVLWEQLHDLEWVNALGALTGNMAVQQVRAGLKAIYLSGWQVAGDANLSGHTYPDQSLYPANSVPQVVRRINNALQRADQIAKIEGDTSVENWLAPIVADGEAGFGGALNVYELQKALIAAGVAGSHWEDQLASEKKSGHLGGKVLIPTQQHIRTLTSARLAADVADVPTVVIARTDAEAATLITSDVDERDQPFITGERTREGFYRTKNGIEPCIARAKAYAPFADLIWMETGTPDLEAARQFSEAVKAEYPDQMLAYNCSPSFNWKKHLDDATIAKFQKELAAMGFKFQFITLAGFHALNYSMFDLAYGYAQNQMSAYVELQEREFAAEERGYTATKHQREVGAGYFDRIATTVDPNSSTTALTGSTEEGQF |
sequence length | 427,427 |
structure length | 427,427 |
publication title |
Structure of isocitrate lyase, a persistence factor of Mycobacterium tuberculosis.
pubmed doi rcsb |
molecule tags | Lyase |
molecule keywords | ISOCITRATE LYASE |
source organism | Mycobacterium tuberculosis h37rv |
ec nomenclature |
ec 4.1.3.1: Isocitrate lyase. ec 4.1.3.1: Isocitrate lyase. |
pdb deposition date | 2000-06-30 |
LinkProt deposition date | 2016-08-22 |
chain | Pfam Accession Code | Pfam Family Identifier | Pfam Description |
---|---|---|---|
AD | PF00463 | ICL | Isocitrate lyase family |
AD | PF00463 | ICL | Isocitrate lyase family |
cath code
| Class | Architecture | Topology | Homology | Domain |
---|---|---|---|---|---|
Alpha Beta | Alpha-Beta Barrel | TIM Barrel | Phosphoenolpyruvate-binding domains | ||
Alpha Beta | Alpha-Beta Barrel | TIM Barrel | Phosphoenolpyruvate-binding domains |
#chains in the LinkProt database with same CATH superfamily 1F8M ABD; 1OY0 ACE; 1O5Q CD; 1OY0 ABD; 1F8I ABD; 1OY0 BD; 1O5Q BCD; 1OY0 BDE; 1F8M ACD; 1OY0 CDE; 1F8M BC; 1F8M AD; 1F8I BD; 1F8I BC; 1O5Q ABD; 1F8I AD; 1F8I AB; 1OY0 CE; 1F8M AC; 1OY0 ABCD; 1OY0 AB; 1F8M ABCD; 1O5Q ABC; 1OY0 ABC; 1O5Q AB; 1F8I BCD; 1F8M BD; 1O5Q AD; 1F8I CD; 1F8M BCD; 1OY0 BCDE; 1OY0 AC; 1O5Q BC; 1F8M AB; 1OY0 ACDE; 1F61 AB; 1F8I ABCD; 1OY0 ABDE; 1OY0 DE; 1OY0 ABCE; 1F8I ACD; 1OQF AB; 1F8M ABC; 1F8I ABC; 1F8M CD; 1O5Q ACD; 1PYM AB; 1O5Q ABCD; 1F8I AC; #chains in the LinkProt database with same CATH topology 1L6W BCFI; 1L6W BCDI; 1L6W ACGJ; 1L6W BCIJ; 1F8M ACD; 1L6W ABCE; 3LGE DFGH; 3LGE BCDH; 1F8M AC; 1L6W BFH; 3LGE BCDE; 3LGE DEF; 1OY0 ACDE; 3LGE ACF; 3LGE ABG; 1L6W BFJ; 1L6W DHJ; 3LGE CFG; 1F8I ABC; 3LGE ACGH; 3LGE ABCD; 1L6W BFHJ; 3LGE AC; 1L6W CDIJ; 3LGE CG; 1O5Q AB; 1L6W ABFH; 1L6W ABDH; 3LGE DEGH; 3LGE ABDG; 3LGE BCEG; 1L6W CDEJ; 1L6W AJ; 1L6W ADFJ; 3LGE BEG; 1L6W ABCI; 1L6W CDGH; 1L6W EI; 1L6W ADEI; 1O5Q BC; 1F8M ABC; 1L6W DEFI; 1OY0 ABDE; 3LGE BE; 3LGE ABFH; 1L6W BDHJ; 3LGE BD; 1L6W DGHJ; 3LGE ACDE; 3LGE BEFG; 3LGE CDE; 3LGE DEFG; 1L6W BCH; 1L6W CFGH; 1L6W AEF; 3LGE BCF; 1L6W BDFH; 1L6W FHIJ; 1L6W CEGI; 1L6W AEGJ; 1L6W ABG; 1F8I BCD; 1L6W BCHI; 1L6W BEFG; 3LGE BCFH; 1L6W DIJ; 3LGE CFH; 1L6W FGJ; 3LGE AEG; 1SR9 AB; 1L6W DFGH; 3LGE ADF; 1L6W CHI; 1L6W DFIJ; 1L6W CI; 1OY0 ABD; 1L6W EGHI; 3LGE ACH; 1L6W HI; 3LGE ABEG; 3LGE CDEF; 3LGE ABE; 3LGE BCFG; 1L6W ABEH; 3LGE DFH; 3LGE ACEH; 1L6W EIJ; 1L6W CHIJ; 1L6W AFG; 1L6W CDHI; 1L6W ACDG; 1L6W AEFG; 1L6W ABFJ; 1L6W BEFI; 1L6W BG; 3LGE ABDE; 3LGE DF; 1F8M CD; 1L6W FGHI; 1L6W BCG; 1L6W DEHJ; 1O5Q CD; 3LGE AH; 1L6W AGIJ; 1L6W ABJ; 1L6W EFGI; 1L6W ABEF; 3LGE DEH; 3LGE ACEF; 3LGE CGH; 1L6W ABCF; 1F8I CD; 1L6W CFGJ; 1OY0 AC; 1L6W ADE; 3LGE ACFG; 1L6W ADEF; 1L6W CFIJ; 1L6W EF; 1L6W ABE; 1L6W AEFI; 1F8I AB; 1L6W BCGH; 1L6W CGH; 1L6W BCEF; 1L6W CDG; 1L6W DHI; 1L6W FGH; 1F8I ACD; 1L6W DFGJ; 3LGE ABCG; 1L6W CIJ; 1F8M ABCD; 1L6W BF; 1L6W BCDF; 1L6W ABHI; 3LGE CD; 1L6W DEI; 1L6W ADIJ; 3LGE CDEH; 1L6W ABEJ; 3LGE BDFH; 1L6W ABCJ; 1L6W ADGH; 3LGE BDEG; 3LGE BCH; 1L6W BCEI; 1L6W ADEJ; 3LGE AG; 1L6W ACDE; 1O5Q BCD; 1F8M BC; 1L6W DGHI; 1L6W CDEF; 1L6W AF; 1L6W CEIJ; 1L6W BDEF; 3LGE AFH; 1L6W ACEI; 1L6W BDGH; 1L6W ACGI; 3LGE AEFH; 1L6W DH; 1L6W AEGI; 1L6W ABH; 1L6W CEFI; 1L6W AGHI; 1L6W CG; 1L6W BCDJ; 3LGE CH; 1L6W EFG; 1L6W ABCD; 3LGE BDG; 1L6W BGH; 1OY0 CDE; 1L6W AHIJ; 1L6W ABC; 1F8I AD; 1OY0 ABC; 3LGE DEG; 3LGE ACE; 1L6W CDE; 1L6W DGH; 3LGE ADGH; 1L6W EHIJ; 1L6W GH; 1O5Q ACD; 1L6W AFIJ; 1OY0 ABCD; 1L6W CGHI; 1L6W DHIJ; 1L6W DEFJ; 3LGE AB; 1L6W BFGJ; 3LGE AEH; 1OY0 BCDE; 3LGE ABH; 3LGE CDGH; 3LGE CF; 1L6W DFHJ; 1L6W EFI; 3LGE ABDF; 3LGE DE; 1OY0 BDE; 1L6W CDEI; 3LGE AGH; 1L6W AIJ; 1L6W CDFJ; 1L6W ABCH; 3LGE BCDG; 1L6W ADGJ; 1L6W EJ; 1L6W ADEH; 3LGE AE; 3LGE BF; 1O5Q AD; 1L6W EFGJ; 1L6W BDHI; 3LGE ABEH; 1L6W CFG; 3LGE ADEF; 1F8I ABCD; 1L6W CDI; 3LGE ACDF; 3LGE CDF; 1L6W CEHI; 1L6W BDH; 1L6W AEG; 1L6W ACDJ; 1L6W ABDJ; 1L6W DJ; 1L6W ABF; 1L6W AEFJ; 1L6W FGIJ; 1L6W BCFH; 1L6W BHI; 1L6W BCDH; 3LGE BFG; 3LGE BCEH; 3LGE BC; 1L6W GHIJ; 3LGE BDE; 1F8M AB; 3LGE AEF; 3LGE ADG; 3LGE AEFG; 1F61 AB; 3LGE AFGH; 3LGE ADEH; 3LGE ACG; 1L6W DEJ; 3LGE CDEG; 1PYM AB; 3LGE ABF; 3LGE CDH; 3LGE ADFG; 1L6W AFGJ; 1L6W FIJ; 1F8I ABD; 1L6W CGIJ; 1OY0 BD; 3LGE ACFH; 3LGE BDEH; 1L6W BFIJ; 1L6W CDHJ; 1L6W ACEG; 1L6W BFGH; 1OY0 CE; 1L6W ABIJ; 3LGE BCDF; 1L6W BEFJ; 1L6W ABGJ; 1L6W DEGH; 3LGE DG; 3LGE BCEF; 1L6W FGHJ; 3LGE BEF; 1L6W BCF; 1L6W CDGI; 1OQF AB; 1L6W DEIJ; 3LGE BCD; 1L6W HIJ; 1L6W AGH; 1L6W AFJ; 1L6W AEIJ; 1L6W DE; 3LGE ABGH; 1OY0 ACE; 1L6W AGHJ; 1L6W EFGH; 3LGE CFGH; 1L6W DEF; 3LGE ADE; 1L6W AB; 1L6W EFIJ; 1L6W BCI; 3LGE BDFG; 1O5Q ABD; 1L6W CFGI; 1OY0 AB; 1F8M BCD; 1L6W BHIJ; 1L6W IJ; 1F8I AC; 1L6W BCFJ; 1OY0 DE; 1L6W DFJ; 1L6W CGI; 3LGE CDFG; 1L6W ABFG; 3LGE BCGH; 3LGE ABC; 1L6W GHI; 1L6W EHI; 1L6W ACFG; 3LGE ABFG; 1L6W CH; 1L6W BCDG; 1L6W ABHJ; 1L6W DEH; 3LGE ABEF; 3LGE ABD; 1L6W EFJ; 1L6W ABEI; 3LGE DH; 1L6W AFGH; 3LGE ACDH; 3LGE BDGH; 3LGE BDEF; 1L6W BFHI; 3LGE AF; 1L6W BEHI; 1L6W ABDE; 1L6W BEFH; 1L6W ABGH; 1F8M ABD; 1L6W CDJ; 3LGE DGH; 1L6W AG; 1L6W BCD; 1L6W DEHI; 1O5Q ABC; 1L6W BEF; 1L6W AGJ; 1L6W AEJ; 3FIG AB; 3LGE AEGH; 1F8M AD; 3LGE CDG; 1L6W CD; 1L6W BCFG; 1L6W ABEG; 1L6W EFHI; 3LGE ACEG; 1L6W CDFG; 1L6W ABCG; 1L6W BDEH; 3LGE BDF; 1L6W DEFG; 1L6W ADEG; 1L6W BGHI; 1L6W CEFG; 1L6W ACG; 3LGE BCE; 3LGE DEFH; 1L6W BCGI; 3LGE ACD; 3LGE DFG; 1L6W BH; 3LGE ADFH; 1OY0 ABCE; 3LGE ABCF; 1L6W BFG; 1F8I BD; 3LGE ABCE; 1L6W BCDE; 1L6W ADHJ; 3LGE CDFH; 1L6W DEFH; 1L6W BC; 1L6W CDEH; 3LGE BDH; 1L6W CDGJ; 1L6W FJ; 3LGE BCG; 3LGE ADH; 1L6W ADJ; 3LGE AD; 1F8I BC; 3LGE BG; 1F8M BD; 3LGE ADEG; 3LGE ABDH; 1L6W FG; 1L6W CDH; 3LGE ACDG; 1L6W CDEG; 1L6W CEI; 1L6W AE; 3LGE AFG; 1L6W ACIJ; 3LGE ABCH; 1L6W AEHI; 1L6W ACGH; 1L6W BDFJ; 1L6W AEI; 1L6W DI; 1L6W AEGH; 1O5Q ABCD; #chains in the LinkProt database with same CATH homology 1F8M ABD; 1OY0 ACE; 1O5Q CD; 1OY0 ABD; 1F8I ABD; 1OY0 BD; 1O5Q BCD; 1OY0 BDE; 1F8M ACD; 1OY0 CDE; 1F8M BC; 1F8M AD; 1F8I BD; 1F8I BC; 1O5Q ABD; 1F8I AD; 1F8I AB; 1OY0 CE; 1F8M AC; 1OY0 ABCD; 1OY0 AB; 1F8M ABCD; 1O5Q ABC; 1OY0 ABC; 1O5Q AB; 1F8I BCD; 1F8M BD; 1O5Q AD; 1F8I CD; 1F8M BCD; 1OY0 BCDE; 1OY0 AC; 1O5Q BC; 1F8M AB; 1OY0 ACDE; 1F61 AB; 1F8I ABCD; 1OY0 ABDE; 1OY0 DE; 1OY0 ABCE; 1F8I ACD; 1OQF AB; 1F8M ABC; 1F8I ABC; 1F8M CD; 1O5Q ACD; 1PYM AB; 1O5Q ABCD; 1F8I AC;
#similar chains in the LinkProt database (?% sequence similarity) ...loading similar chains, please wait... #similar chains, but unlinked ...loading similar chains, please wait... #similar chains in the pdb database (?% sequence similarity) ...loading similar chains, please wait...